Results 11 to 20 of about 227,715 (371)

Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Elevated in Bronchoalveolar Lavage Fluid of Patients with Acute Respiratory Distress Syndrome. [PDF]

open access: yesPLoS ONE, 2016
INTRODUCTION:Pulmonary vascular endothelial activation has been implicated in acute respiratory distress syndrome (ARDS), yet little is known about the presence and role of endothelial activation markers in the alveolar space in ARDS.
Engi F Attia   +4 more
doaj   +1 more source

Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients

open access: yesEmerging Microbes and Infections, 2020
Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak has caused devastating mortality and posed a great threat to public health.
Yong Xiong   +18 more
semanticscholar   +1 more source

Bronchoalveolar lavage results are independent of season, age, gender and collection site. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Clinical interpretation of bronchoalveolar lavage fluid results is dependent on the availability of reference values for healthy individuals.
Helga H Olsen   +4 more
doaj   +1 more source

Bronchoalveolar lavage fluid cytological findings in healthy Amiata donkeys [PDF]

open access: yesOpen Veterinary Journal, 2021
Background: The approach to respiratory diseases in donkeys is similar to that for horses, nevertheless bronchoalveolar fluid (BALF) and tracheal wash (TW) cytology in this species have been described only a few times in the literature.
Valentina Vitale   +3 more
doaj   +1 more source

Blood and Bronchoalveolar Lavage Fluid Metagenomic Next-Generation Sequencing in Pneumonia

open access: yesThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2020
Background Metagenomic next-generation sequencing (mNGS) has made a revolution in the mode of pathogen identification. We decided to explore the diagnostic value of blood and bronchoalveolar lavage fluid (BALF) as mNGS samples in pneumonia.
Xu Chen   +19 more
semanticscholar   +1 more source

HLA predictions from the bronchoalveolar lavage fluid samples of five patients at the early stage of the Wuhan seafood market COVID-19 outbreak [PDF]

open access: yesBioinformatics, btaa756 (2020), 2020
We are in the midst of a global viral pandemic, one with no cure and a high mortality rate. The Human Leukocyte Antigen (HLA) gene complex plays a critical role in host immunity. We predicted HLA class I and II alleles from the transcriptome sequencing data prepared from the bronchoalveolar lavage fluid samples of five patients at the early stage of ...
arxiv   +1 more source

Exosomes and their roles in the chemoresistance of pancreatic cancer

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022
Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan   +4 more
wiley   +1 more source

Pharmacokinetics and Bioequivalence of Fudosteine in Healthy Chinese Volunteers Under Fasting and Fed Conditions: A 4‐Way Replicate Crossover Study

open access: yesClinical Pharmacology in Drug Development, Volume 12, Issue 1, Page 30-37, January 2023., 2023
Abstract The bioequivalence of a generic fudosteine tablet vs a brand‐named fudosteine tablet under fasting and fed conditions was evaluated in this study. This randomized, open‐label, single‐dose, 4‐way replicate, crossover, bioequivalence study included 64 healthy Chinese subjects (fasting cohort, n = 32; fed cohort, n = 32) who were assigned to ...
Mingxue Zhu   +6 more
wiley   +1 more source

Pleural CD14+ monocytes/macrophages of healthy adolescents show a high expression of metallothionein family genes

open access: yesEuropean Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
Modern surgical (technical) possibilities enable pleural macrophage isolation and analyses regardless the person`s age. Transcriptome profiling of macrophages from healthy or sick individuals revealed that these cells express high levels of metallothioneins, metal‐binding proteins that are involved in heavy metal detoxification, antioxidative defense ...
Nagoud Schukfeh   +11 more
wiley   +1 more source

Pyrus ussuriensis Maxim 70% ethanol eluted fraction ameliorates inflammation and oxidative stress in LPS‐induced inflammation in vitro and in vivo

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 458-469, January 2023., 2023
In this work, we demonstrated that PUM70 specifically suppressed LPS‐mediated inflammatory responses. Notably, PUM70 treatment inhibited LPS‐induced lung damage, pro‐inflammatory cytokine production, and reduced macrophage infiltration in the lungs. Mechanistically, PUM70 suppressed LPS‐induced inflammation and oxidative stress via the Nrf2/HO‐1 and ...
Fei Peng, Xin Ren, Bin Du, Yuedong Yang
wiley   +1 more source

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