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Clinics in Chest Medicine, 2014
Bronchodilators are central in the symptomatic treatment of chronic obstructive pulmonary disease (COPD), although there is often limited reversibility of airflow obstruction. Three classes of bronchodilators (β2-agonists, antimuscarinic agents, methylxanthines) are currently available, which can be used individually, or in combination with each other ...
Cazzola M, MATERA, Maria Gabriella
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Bronchodilators are central in the symptomatic treatment of chronic obstructive pulmonary disease (COPD), although there is often limited reversibility of airflow obstruction. Three classes of bronchodilators (β2-agonists, antimuscarinic agents, methylxanthines) are currently available, which can be used individually, or in combination with each other ...
Cazzola M, MATERA, Maria Gabriella
openaire +6 more sources
Journal of the American Medical Association, 1952
Visammin (khellin) is a crystalline derivative of the Middle-Eastern plant Ammi visnaga lam; it was identified as a dimethoxy-methyl-furano chromone 1 and was synthesized in 1949. 2 Samaan's 3 pharmacologic studies in the early 1930's indicated that the drug relaxed isolated muscle preparations from the bronchus of the pig and dog by a direct effect on
G. L. Snider +3 more
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Visammin (khellin) is a crystalline derivative of the Middle-Eastern plant Ammi visnaga lam; it was identified as a dimethoxy-methyl-furano chromone 1 and was synthesized in 1949. 2 Samaan's 3 pharmacologic studies in the early 1930's indicated that the drug relaxed isolated muscle preparations from the bronchus of the pig and dog by a direct effect on
G. L. Snider +3 more
openaire +3 more sources
Journal of Applied Physiology, 1992
Recent advances in computed tomographic imaging provide a unique method to serially and directly visualize acute physiological response in the lung. To directly investigate the airway response to hypoxia, high-resolution computed tomographic scans of the lungs of eight intact anesthetized minipigs were serially repeated before, during, and after ...
R C, Wetzel +3 more
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Recent advances in computed tomographic imaging provide a unique method to serially and directly visualize acute physiological response in the lung. To directly investigate the airway response to hypoxia, high-resolution computed tomographic scans of the lungs of eight intact anesthetized minipigs were serially repeated before, during, and after ...
R C, Wetzel +3 more
openaire +2 more sources
, 1994
Objective. —To determine whether a program incorporating smoking intervention and use of an inhaled bronchodilator can slow the rate of decline in forced expiratory volume in 1 second (FEV 1 ) in smokers aged 35 to 60 years who have mild obstructive ...
N. Anthonisen +97 more
semanticscholar +1 more source
Objective. —To determine whether a program incorporating smoking intervention and use of an inhaled bronchodilator can slow the rate of decline in forced expiratory volume in 1 second (FEV 1 ) in smokers aged 35 to 60 years who have mild obstructive ...
N. Anthonisen +97 more
semanticscholar +1 more source
Pharmacology and Therapeutics of Bronchodilators
Pharmacological Reviews, 2012Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of the current management of chronic obstructive pulmonary disease (COPD) and are critical in the symptomatic management of asthma, although controversies around the use of these drugs remain. Bronchodilators work through their direct relaxation effect on airway
Cazzola M +3 more
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Current Opinion in Pharmacology, 2012
Bronchodilators are central in the treatment of airway diseases including chronic obstructive pulmonary disease (COPD). Bronchodilators in COPD aim to improve lung function, reduce symptoms, prevent exacerbation, and enhance quality of life. The majority of programs in development for novel bronchodilators are focused on enhancing existing targets to ...
Garbo, Mak, Nicola A, Hanania
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Bronchodilators are central in the treatment of airway diseases including chronic obstructive pulmonary disease (COPD). Bronchodilators in COPD aim to improve lung function, reduce symptoms, prevent exacerbation, and enhance quality of life. The majority of programs in development for novel bronchodilators are focused on enhancing existing targets to ...
Garbo, Mak, Nicola A, Hanania
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Clinics in Chest Medicine, 1989
Bronchodilator response is usually tested to establish reversibility of airflow obstruction, to aid in diagnosis, and to help plan long-term bronchodilator therapy. Among the various tests to establish bronchodilator response, FEV1, FEF25-75% or FEF50%, and FVC are the most widely used.
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Bronchodilator response is usually tested to establish reversibility of airflow obstruction, to aid in diagnosis, and to help plan long-term bronchodilator therapy. Among the various tests to establish bronchodilator response, FEV1, FEF25-75% or FEF50%, and FVC are the most widely used.
openaire +2 more sources