Results 131 to 140 of about 3,178,532 (212)
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Degradation of Bronchodilator Agents in Oxymix System

Journal of Pharmaceutical Sciences, 1973
Abstract: Known amounts of isoproterenol, phenylephrine, and epinephrine were added to the aqueous oxymix system and thereby exposed to potential redox destruction. Thirty minutes later, recoveries of isoproterenol and phenylephrine were 89-100% and 89-108%, respectively, while the recovery of epinephrine was 53-79%.
George H. Kronberg, Bertil H. Takman
openaire   +4 more sources

In vitro studies on the relative potency of bronchodilator agents

Lung, 1985
This study describes a rapid in vitro assay for the order of potency of bronchodilator drugs using specific binding of (−)-[3H] dihydroalprenolol ([3H]DHA) to rat lung membranes. Under linear conditions with respect to tissue, specific binding of [3H]DHA showed saturability, rapid kinetics of association and dissociation of radioligand, and ...
Joseph H. Fleisher, Jacob L. Pinnas
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Humidification, Nebulization, and Bronchodilator Agents

1978
These defense mechanisms include: (a) ciliary escalator system—the mucus carpet carrying microorganisms and small foreign particles at a normal rate of about 1 cm/min from bronchioles and bronchi to the larynx entrance, (b) coughing, and (c) phagocytosis—macrophages in alveoli clearing via interstitial spaces (lymphatics) and upward via the ciliary ...
P. Safar
openaire   +3 more sources

Bronchodilator Responses to Anticholinergic and Beta-Adrenergic Agents in Acute and Stable COPD

Chest, 1991
Patients with COPD may respond differently to anticholinergic and beta-agonist bronchodilators. Previously, in acutely ill COPD patients, we showed similar improvements in pulmonary function after each drug (study 1). The responses of the same patients when stable are now reported (study 2). Patients received ipratropium bromide (54 micrograms) (n = 16)
J. Karpel
openaire   +4 more sources

Use of a technique for measuring pulmonary resistance to airflow for the pharmacological evaluation of bronchodilator agents

Journal of Pharmaceutical Sciences, 1967
A technique for measuring pulmonary resistance to airflow without the interference of compliance changes was used to obtain data on the bronchodilator activity of ephedrine sulfate and methoxyphenamine hydrochloride. The resting pulmonary resistance of cats was increased by injecting histamine (100 mcg., base, i.v.) or 5-hydroxytryptophan creatinine ...
Leon C. Greene   +2 more
openaire   +4 more sources

[Measurement of the effect of a bronchodilator agent].

open access: closedSchweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1990
Response in a bronchodilator must be expressed by the combining the largest amplitude of response with the highest reproducibility. The forced expiratory volume in the first second (FEV1) meets these conditions and thus represents the best test. The bronchodilator response is commonly expressed in percent of the initial FEV1.
Fitting Jw
openaire   +2 more sources

SC-10049: A CATECHOLAMINE BRONCHODILATOR AND HYPERGLYCEMIC AGENT

open access: closedThe Journal of Pharmacology and Experimental Therapeutics, 1961
C G, VAN ARMAN   +2 more
openaire   +3 more sources

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