Results 131 to 140 of about 3,178,532 (212)
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Degradation of Bronchodilator Agents in Oxymix System
Journal of Pharmaceutical Sciences, 1973Abstract: Known amounts of isoproterenol, phenylephrine, and epinephrine were added to the aqueous oxymix system and thereby exposed to potential redox destruction. Thirty minutes later, recoveries of isoproterenol and phenylephrine were 89-100% and 89-108%, respectively, while the recovery of epinephrine was 53-79%.
George H. Kronberg, Bertil H. Takman
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In vitro studies on the relative potency of bronchodilator agents
Lung, 1985This study describes a rapid in vitro assay for the order of potency of bronchodilator drugs using specific binding of (−)-[3H] dihydroalprenolol ([3H]DHA) to rat lung membranes. Under linear conditions with respect to tissue, specific binding of [3H]DHA showed saturability, rapid kinetics of association and dissociation of radioligand, and ...
Joseph H. Fleisher, Jacob L. Pinnas
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Comparative evaluation of epinephrine and aminophylline as bronchodilator agents.
Ross C. Kory+2 more
semanticscholar +5 more sources
Humidification, Nebulization, and Bronchodilator Agents
1978These defense mechanisms include: (a) ciliary escalator system—the mucus carpet carrying microorganisms and small foreign particles at a normal rate of about 1 cm/min from bronchioles and bronchi to the larynx entrance, (b) coughing, and (c) phagocytosis—macrophages in alveoli clearing via interstitial spaces (lymphatics) and upward via the ciliary ...
P. Safar
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Bronchodilator Responses to Anticholinergic and Beta-Adrenergic Agents in Acute and Stable COPD
Chest, 1991Patients with COPD may respond differently to anticholinergic and beta-agonist bronchodilators. Previously, in acutely ill COPD patients, we showed similar improvements in pulmonary function after each drug (study 1). The responses of the same patients when stable are now reported (study 2). Patients received ipratropium bromide (54 micrograms) (n = 16)
J. Karpel
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Journal of Pharmaceutical Sciences, 1967
A technique for measuring pulmonary resistance to airflow without the interference of compliance changes was used to obtain data on the bronchodilator activity of ephedrine sulfate and methoxyphenamine hydrochloride. The resting pulmonary resistance of cats was increased by injecting histamine (100 mcg., base, i.v.) or 5-hydroxytryptophan creatinine ...
Leon C. Greene+2 more
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A technique for measuring pulmonary resistance to airflow without the interference of compliance changes was used to obtain data on the bronchodilator activity of ephedrine sulfate and methoxyphenamine hydrochloride. The resting pulmonary resistance of cats was increased by injecting histamine (100 mcg., base, i.v.) or 5-hydroxytryptophan creatinine ...
Leon C. Greene+2 more
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[Measurement of the effect of a bronchodilator agent].
Response in a bronchodilator must be expressed by the combining the largest amplitude of response with the highest reproducibility. The forced expiratory volume in the first second (FEV1) meets these conditions and thus represents the best test. The bronchodilator response is commonly expressed in percent of the initial FEV1.
Fitting Jw
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SC-10049: A CATECHOLAMINE BRONCHODILATOR AND HYPERGLYCEMIC AGENT
C G, VAN ARMAN+2 more
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New Bronchodilator Joins Group of Environmentally Friendly Agents
DAMIAN MCNAMARA
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