Multifactorial Determinants of Refractory Breathlessness in COPD: Development of the Refractory Breathlessness Score for Risk Stratification. [PDF]
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GOLD 2026: Transforming COPD Management with Early Intervention, Multi-dimensional Assessment, and Personalized Care. [PDF]
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Degradation of Bronchodilator Agents in Oxymix System
Journal of Pharmaceutical Sciences, 1973Abstract: Known amounts of isoproterenol, phenylephrine, and epinephrine were added to the aqueous oxymix system and thereby exposed to potential redox destruction. Thirty minutes later, recoveries of isoproterenol and phenylephrine were 89-100% and 89-108%, respectively, while the recovery of epinephrine was 53-79%.
G H, Kronberg, B H, Takman
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New isoquinolines as potential bronchodilator agents
Tetrahedron, 1973Abstract The syntheses of 5-hydroxy-6-hydroxymethyl, 6-hydroxy-7-hydroxymethyl and 7-hydroxy-6-hydroxymethyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolines ( 1d ), ( 1b ) and ( 1c ) respectively, are described.
S F Dyke
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Humidification, Nebulization, and Bronchodilator Agents
1978These defense mechanisms include: (a) ciliary escalator system—the mucus carpet carrying microorganisms and small foreign particles at a normal rate of about 1 cm/min from bronchioles and bronchi to the larynx entrance, (b) coughing, and (c) phagocytosis—macrophages in alveoli clearing via interstitial spaces (lymphatics) and upward via the ciliary ...
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In vitro studies on the relative potency of bronchodilator agents
Lung, 1985This study describes a rapid in vitro assay for the order of potency of bronchodilator drugs using specific binding of (−)-[3H] dihydroalprenolol ([3H]DHA) to rat lung membranes. Under linear conditions with respect to tissue, specific binding of [3H]DHA showed saturability, rapid kinetics of association and dissociation of radioligand, and ...
J H, Fleisher, J L, Pinnas
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