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Hypoxic bronchodilation

Journal of Applied Physiology, 1992
Recent advances in computed tomographic imaging provide a unique method to serially and directly visualize acute physiological response in the lung. To directly investigate the airway response to hypoxia, high-resolution computed tomographic scans of the lungs of eight intact anesthetized minipigs were serially repeated before, during, and after ...
R C, Wetzel   +3 more
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New bronchodilators

Current Opinion in Pharmacology, 2012
Bronchodilators are central in the treatment of airway diseases including chronic obstructive pulmonary disease (COPD). Bronchodilators in COPD aim to improve lung function, reduce symptoms, prevent exacerbation, and enhance quality of life. The majority of programs in development for novel bronchodilators are focused on enhancing existing targets to ...
Garbo, Mak, Nicola A, Hanania
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VISAMMIN AS BRONCHODILATOR

Journal of the American Medical Association, 1952
Visammin (khellin) is a crystalline derivative of the Middle-Eastern plant Ammi visnaga lam; it was identified as a dimethoxy-methyl-furano chromone 1 and was synthesized in 1949. 2 Samaan's 3 pharmacologic studies in the early 1930's indicated that the drug relaxed isolated muscle preparations from the bronchus of the pig and dog by a direct effect on
G L, SNIDER   +3 more
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Bronchodilators for bronchiolitis

1999
Bronchiolitis is an acute, highly communicable lower respiratory tract infection. Bronchodilators are commonly used in the management of bronchiolitis in North America, but not in the United Kingdom. The objective of this review was to assess the effects of bronchodilators for bronchiolitis.We searched MEDLINE, EMBASE, Reference Update, reference lists
J D, Kellner   +3 more
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Response to Bronchodilators

Clinics in Chest Medicine, 1989
Bronchodilator response is usually tested to establish reversibility of airflow obstruction, to aid in diagnosis, and to help plan long-term bronchodilator therapy. Among the various tests to establish bronchodilator response, FEV1, FEF25-75% or FEF50%, and FVC are the most widely used.
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The Ideal Bronchodilator

Archives of Internal Medicine, 1979
From the clinician's standpoint, an ideal bronchodilator should have (1) selectivity for bronchial smooth muscle, (2) minimal stimulatory effects on the cardiovascular and central nervous system, (3) prolonged action, (4) rapid onset of action, and (5) oral effectiveness for patient convenience. In addition, bronchodilation should occur in both central
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[Bronchodilators].

La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1984
Bronchodilating drugs can be divided into three main groups: beta-adrenergic stimulants including specific beta-2 receptor agonists (salbutamol, terbutaline, fenoterol) which are the agents of this group used in everyday practice, theophylline and its derivatives, and atropine-like drugs (ipratropium bromide). Bronchodilators act chiefly upon the spasm
C, Advenier, J, Cerrina, P, Duroux
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Bronchodilators

Current Opinion in Pulmonary Medicine, 1997
After complete abstinence, regular use of short-acting beta 2-agonists results in an increase in early and late asthmatic (allergen) response, exercise-induced bronchoconstriction, and nonspecific airways responsiveness (methacholine). Regular use of long-acting beta 2-agonists also results in increased nonspecific airways responsiveness (methacholine)
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