Results 31 to 40 of about 25,067 (232)

Dyspnoea-referenced minimal clinically important difference in the resting inspiratory capacity response to short-acting bronchodilators in COPD patients

Pulmonology
Background In COPD, the clinical significance of bronchodilator-induced changes in inspiratory capacity (IC) at rest remains uncertain. Unlike forced expiratory volume in one second (FEV1), IC may better reflect symptom improvement, but no minimal ...
Pierantonio Laveneziana, David Hajage, Nicolas Verger, Clara Bianquis, François-Xavier Blanc, Christian Straus, Thomas Similowski   +6 more
doaj   +1 more source

Oscillometric assessment of bronchodilator response in horses with severe asthma during remission

Equine Veterinary Journal, EarlyView.
Abstract Background During clinical remission of severe equine asthma (SEA), affected animals can be challenging to distinguish from healthy horses. In humans, the degree of bronchodilation achieved with a β2‐adrenergic bronchodilator is helpful in differentiating asthmatics from healthy subjects.
Séléna de Wasseige, Sophie Mainguy‐Seers, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Spreading quality improvement in bronchiolitis care: A qualitative study of barriers and facilitators to de‐implementation efforts across Alberta′s healthcare settings

Journal of Hospital Medicine, EarlyView.
Abstract Background Low‐value care remains prevalent in bronchiolitis management despite evidence‐based guidelines. De‐implementation initiatives face unique challenges compared with traditional implementation efforts, particularly when spreading across diverse healthcare settings.
Nathan M. Solbak, Ashleigh Jensen, Erin Thompson, Aaron Peterson, Lily Ragan, Daina Thomas, David W. Johnson, J. A. Michelle Bailey   +7 more
wiley   +1 more source

Inhaled corticosteroids for chronic obstructive pulmonary disease: what is their role in therapy?

International Journal of COPD, 2018
Donald P Tashkin,1 Charlie Strange2 1Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; 2Department of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC, USA
Tashkin DP, Strange C
doaj  

Therapeutic‐dose verapamil‐induced cardiogenic shock in an older patient: a case report

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Calcium channel blocker (CCB) toxicity most commonly follows deliberate overdose. However, severe toxicity at therapeutic doses may occur in susceptible individuals. Severe CCB toxicity often presents with clinical features of bradycardia, hypotension, hyperglycaemia, and lactic acidosis.
Christopher Thuring, Maria Carey, Timothy Webber, Biswadev Mitra   +3 more
wiley   +1 more source

Superior Labial Artery Flap for Septal Perforation Repair: The Boxer's Flap

The Laryngoscope, EarlyView.
The nasal floor flap, or Boxer's flap, is an anteriorly pedicled, superior labial artery–based mucosal flap that provides excellent closure rates in septal perforation repair when traditional septal flaps are not feasible. The schematic shows: (A) preoperative perforation, (B) nasal floor flap elevation (with the pedicle maintained at the inferior ...
Nicholas J. Campion, Zhanna Mokoyan, Viktoriya Stepanova, Isam Alobid, Richard J. Harvey, Yury Rusetsky   +5 more
wiley   +1 more source

AMPLIFY: a randomized, Phase III study evaluating the efficacy and safety of aclidinium/formoterol vs monocomponents and tiotropium in patients with moderate-to-very severe symptomatic COPD

International Journal of COPD, 2019
Sanjay Sethi,1 Edward Kerwin,2 Henrik Watz,3 Gary T Ferguson,4 Robert M Mroz,5,6 Rosa Segarra,7 Eduard Molins,7 Diana Jarreta,7 Esther Garcia Gil7 1Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, NY, USA ...
Sethi S, Kerwin E, Watz H, Ferguson GT, Mroz RM, Segarra R, Molins E, Jarreta D, Garcia Gil E   +8 more
doaj  

Effects of Age on 1-Second Forced Expiratory Volume Response to Bronchodilation

International Journal of Gerontology, 2009
Background: The bronchodilation test is used to detect reversible airways obstruction, considered important for diagnosing asthma. However, little is known about the effects of age on the bronchodilation response.
Ching-Lung Liu, Chien-Liang Wu, Yen-Ta Lu   +2 more
doaj   +1 more source

High‐Flow Nasal Oxygen in Early Home Pulmonary Rehabilitation for Exertional Hypoxaemia: A Pilot Randomised Feasibility Trial

Respirology, EarlyView.
Summary This pilot randomised feasibility trial evaluated the feasibility and acceptability of early, intensive home‐based pulmonary rehabilitation (PR) and high‐flow nasal oxygen (HFO) during exercise in patients with exertional hypoxaemia post‐hospitalisation. Early home‐based PR was feasible and safe.
Yingjuan Mok, Jing Wen Foong, Hang Siang Wong, Edwin Chan Shih‐Yen, Norasyikin Hassan, Piyanee Klainin‐Yobas, Li Ching Soh, Amanda Soh, Shi Hua Tan, Xuan Han Koh, Poh Choo Tan, Keith Keat Huat Wong   +11 more
wiley   +1 more source

Biomarkers of Pre‐COPD Lung Function Trajectories in Middle Age: A Prospective Study From 1st to 6th Decade

Respirology, EarlyView.
Identifying impaired lifetime lung function trajectories is key to identifying the preclinical phase of COPD (Pre‐COPD) or prognosis of COPD. We have identified that some circulating established COPD biomarkers differ across ‘pre‐COPD’ lung function trajectories, suggesting that some COPD‐specific pathobiological processes, including inflammation, are ...
Dinh S. Bui, Don Vicendese, Jonathan Pham, Nur Sabrina Idrose, Adrian Lowe, Caroline Lodge, Raisa Cassim, Chamara Senaratna, Gayan Bowatte, Garun Hamilton, Alan James, Paul Thomas, Richard Wood‐Baker, Peter Frith, Gary Anderson, Philip M. Hansbro, Graeme Zosky, George Washko, Michael J. Abramson, Rosa Faner, Alvar Agusti, Jennifer Perret, E. Haydn Walters, Shyamali C. Dharmage   +23 more
wiley   +1 more source