Results 61 to 70 of about 23,220 (218)

Multiomics endotyping of preterm infants with bronchopulmonary dysplasia and pulmonary hypertension—A pilot study

Pulmonary Circulation, 2023
Pulmonary hypertension associated with bronchopulmonary dysplasia is a severe complication of preterm birth resulting in high mortality of up to 50% within the first 2 years of life.
Roopa Siddaiah, Christiana Oji‐Mmuo, Vincent P. R. Aluquin, Yuka Imamura Kawasawa, Ann Donnelly, Dustin Rousselle, Nathalie Fuentes, Eric D. Austin, Patricia Silveyra   +8 more
doaj   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell‐Derived Microvesicles Alleviate Bronchopulmonary Dysplasia in Preterm Rats by Inhibiting Neutrophil Extracellular Trap Formation

Pediatric Discovery, EarlyView.
Excessive neutrophil extracellular trap (NET) extrusion (NETosis) links prenatal inflammation to bronchopulmonary dysplasia (BPD) pathogenesis. Treatment with human umbilical cord mesenchymal stem cell‐derived microvesicles suppresses NET formation, reduces lung injury, and promotes alveolarization in a preterm rat model, offering a promising cell‐free
Yi Lu, Wen Tan, Xiao Yang, Tingting Luo, Chenghao Mei, Huaqin Bu, Jinhua Ma, Chao Gong, Li Zhong, Ou Zhou, Daiyin Tian   +10 more
wiley   +1 more source

Fetuses exposed to an episode of threatened preterm labor delivered at or near term show signs of cardiac remodeling

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To evaluate whether fetuses exposed to threatened preterm labor (PTL) without intra‐amniotic infection or inflammation (IAI), who were born ≥ 34 weeks' gestation, show signs of cardiac remodeling and dysfunction at admission and 4 weeks after the episode of threatened PTL.
C. Murillo, M. Palacio, C. Rueda, M. Larroya, D. Boada, J. Ponce, M. Guilleumes, O. Gómez, S. Ferrero, E. Gratacós, F. Crispi, T. Cobo   +11 more
wiley   +1 more source

The new bronchopulmonary dysplasia [PDF]

Current Opinion in Pediatrics, 2011
Bronchopulmonary dysplasia (BPD) remains the most common severe complication of preterm birth. A number of recent animal models and clinical studies provide new information about pathophysiology and treatment.The epidemiology of BPD continues to demonstrate that birth weight and gestational age are most predictive of BPD.
openaire   +2 more sources

Pathogenesis of Bronchopulmonary Dysplasia [PDF]

Respiration, 2009
Bronchopulmonary dysplasia (BPD) refers to a heterogeneous group of lung disorders in infants that is commonly associated with prematurity and surfactant deficiency. BPD results from the complex interplay between impairments in the premature lung such as surfactant deficiency, perinatal insults such as infection, and damage resulting from supportive ...
Don, Hayes, David J, Feola, Brian S, Murphy, Lori A, Shook, Hubert O, Ballard   +4 more
openaire   +2 more sources

Genotype‐directed therapy for non–small cell lung cancer diagnosed during pregnancy: A pooled analysis of seven cases from the Cancer and Pregnancy Registry with maternal and neonatal outcomes and review of the literature

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this retrospective case series from a single database of pregnant women with cancer, seven were diagnosed with non‐small cell lung cancer (NSCLC). Chemotherapy and in some cases also biomarker‐directed therapy during pregnancy were associated with disease control allowing delivery closer to term and resulting in improved maternal outcomes compared ...
Reed Firestone, Elyce Cardonick
wiley   +1 more source

Post-translational modifications and bronchopulmonary dysplasia

Frontiers in Pediatrics
Bronchopulmonary dysplasia is a prevalent respiratory disorder posing a significant threat to the quality of life in premature infants. Its pathogenesis is intricate, and therapeutic options are limited. Besides genetic coding, protein post-translational
Kun Yang, Ting He, Xue Sun, Wenbin Dong
doaj   +1 more source

Prognostic models for predicting sight‐threatening retinopathy of prematurity in preterm infants: A systematic review

Acta Ophthalmologica, EarlyView.
Abstract To identify, describe and critically appraise studies developing and/or validating models for predicting sight‐threatening retinopathy of prematurity (ROP) in preterm infants undergoing screening in neonatal intensive care units. PubMed, Embase via Ovid, trial registers, and grey literature were searched from inception to 21 October 2025 ...
Stella Moutzouri, Anna‐Bettina Haidich, Aikaterini K. Seliniotaki, Maria Lithoxopoulou, Persefoni Talimtzi, Christos Tsakalidis, Nikolaos Ziakas, Asimina Mataftsi   +7 more
wiley   +1 more source

Effect of delayed cord clamping on the risk of bronchopulmonary dysplasia in preterm infants with respiratory distress

BMC Pediatrics
Purpose To assess the incidence of bronchopulmonary dysplasia in preterm infants born at
Jiajing Ge, Chenhong Wang, Huijia Lin, Guannan Bai, Yanping Xu, Liping Shi, Xiaolu Ma, Zheng Chen   +7 more
doaj   +1 more source

THESS‐ROP study: Development of a prediction model for treatment‐warranted retinopathy of prematurity and external validation of postnatal weight‐gain‐based models in Greece

Acta Ophthalmologica, EarlyView.
Abstract Purpose To develop THESS‐ROP, a novel prediction model for treatment‐warranted retinopathy of prematurity (TW‐ROP) and compare its performance with four established models in a Greek cohort of consecutively screened preterm infants. Methods This ambispective cohort study included all 526 infants screened for ROP (2016–2022) at the 2nd ...
Stella Moutzouri, Anna‐Bettina Haidich, Maria Lithoxopoulou, Georgios Pappas, Christos Tsakalidis, Nikolaos Ziakas, Asimina Mataftsi   +6 more
wiley   +1 more source