Results 71 to 80 of about 29,783 (290)

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

open access: yesAdvanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei   +12 more
wiley   +1 more source

TO THE QUESTION OF PARTICIPATION OF THE LOCAL ENEOLITHIC POPULATION OF NORTHERN KULUNDA IN THE FORMATION OF THE EARLY BRONZE AGE CULTURES OF BARNAUL-BIYSK OB’ RIVER REGION

open access: yesВестник Кемеровского государственного университета, 2015
The participation of the local Eneolithic population in the process of formation of the Elunino culture had already been reflected in the scientific literature.
Yu. F. Kiryushin, K. Yu. Kiryushin
doaj  

AI‐Directed 3D Printing of Hierarchical Polyurethane Foams

open access: yesAdvanced Science, EarlyView.
Digitally guided direct ink writing, combined with AI‐generated design, enables the fabrication of hierarchical polyurethane foams with tunable multiscale porosity. This approach produces architected foams featuring interconnected open‐cell networks and tailored mechanical properties, advancing the development of adaptive, high‐performance materials ...
Dhanush Patil   +15 more
wiley   +1 more source

Now we’re Cooking with Gas! How Experimental Archaeology Challenges Modern Assumptions about Metal Recycling

open access: yesEXARC Journal, 2017
It is accepted knowledge that when re-melting alloys, some of the metal with a lower melting temperature is lost through oxidation, and more metal must be added in order to maintain the desired alloy proportions.
E. Giovanna Fregni
doaj  

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

open access: yesAdvanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen   +11 more
wiley   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

Changes in spectra of cultivated and gathered plants in the Bronze Age

open access: yesArcheologické Rozhledy
The Bronze Age (BA) in Central Europe witnessed significant transformations in various aspects of human activities. This study focuses on changes in subsistence strategies during the BA, represented by the assortment of edible plants.
Adéla Pokorná   +2 more
doaj   +1 more source

AIEgen‐Based Proactive Early Warning System and Precise Treatment Strategy for Monkeypox Prevention and Control

open access: yesAdvanced Science, EarlyView.
An intelligent early warning and treatment system for monkeypox, utilizing a sprayable AIEgen‐ liquid dressing (AIE@LD) that responds to lesion pH. Integrated with a smartphone app and cloud platform, it enables real‐time infection detection via fluorescence imaging and triggers on‐demand photodynamic therapy under white light, effectively eradicating ...
Wei Wang   +14 more
wiley   +1 more source

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