Results 101 to 110 of about 1,726 (204)

Sensing‐Integrated Patient‐Derived Tumorspheres Predict Chemotherapeutic Efficacy via Local Extracellular pH Dynamics

Small, EarlyView.
The study introduces a 3D sensing‐integrated platform enabling real‐time, non‐invasive monitoring of pH dynamics in patient‐derived PDAC tumorspheres. It revealed distinct extracellular acidification patterns under FOLFIRINOX, gemcitabine, and paclitaxel, correlating with therapeutic efficacy.
Stefania Forciniti, Valentina Onesto, Anna Chiara Siciliano, Helena Iuele, Stefano D'Ugo, Norma Depalma, Cinzia Fasano, Alessandro D'Amuri, Giuseppe Gigli, Marcello G. Spampinato, Loretta L. del Mercato   +10 more
wiley   +1 more source

Vat Polymerization 3D Printing of Hydrogels With Tunable Porosity

Small Methods, EarlyView.
Nanodroplet emulsion templating enables DLP printing of porous hydrogels with pore sizes tunable across two orders of magnitude, from 46.15 to 0.66 µm. The printed interconnected networks retain high fidelity while improving mechanical robustness and cellular responses, providing a versatile platform for porous hydrogel biofabrication.
Liwei Liu, Liwen Zhang, Xumin Huang, Yuan Xu, Jason R. Stokes, Jinghan Qin, Yi Du, Dandan Cui, Xinyan Gu, Naufal Kabir Ahamed Nasar, Xiaoming Sun, Jiali Zhai, Thomas P. Davis, Ruirui Qiao   +13 more
wiley   +1 more source

Sargassum Lung Syndrome: Air Flow Obstruction and Bronchial Inflammation Are Observed After Prolonged Exposure to Sargassum Gas Emissions in the Eastern Caribbean

Environmental Toxicology, EarlyView.
ABSTRACT Sargassum inundation of Caribbean and American shorelines is a growing environmental hazard. Hydrogen sulfide (H2S) and ammonia (NH3) produced by decomposing Sargassum could be involved in airway obstruction and bronchial inflammation. The study was undertaken to evaluate the effects of exposure to H2S and NH3 gases emitted during Sargassum ...
Rishika Banydeen, Jonathan Florentin, Maxime Boutourlinsky, Remi Nguyen, Fatima Radouani, Moustapha Agossou, Gary Lutin, Thierry Lebrun, Remi Neviere, Dabor Resiere   +9 more
wiley   +1 more source

Context‐Dependent Effects of Beavers (Castor spp.) on Freshwater Pearl Mussels (Margaritifera margaritifera) in European Rivers 河狸对欧洲河流中的淡水珍珠贝 (Margaritifera margaritifera) 存在情境依赖性影响

Wildlife Letters, EarlyView.
The study explores how beavers (Castor spp.) affect endangered freshwater pearl mussels (Margaritifera margaritifera) in European rivers. Beaver dams can harm small, fragmented mussel populations by reducing flow, increasing sediment, and potentially limiting host fish movement, while larger populations may benefit from improved bed stability and ...
Louise Lavictoire, Ian Convery, Ben Strachan   +2 more
wiley   +1 more source

Crystal structure of fucoxanthin: resolving a long‐standing crystallographic challenge

Acta Crystallographica Section C, EarlyView.
The first small‐molecule single‐crystal X‐ray structure of fucoxanthin is reported, resolving a long‐standing crystallographic problem in carotenoid structural chemistry.Fucoxanthin (C42H58O6) is a highly functionalized allenic epoxy xanthophyll containing hydroxy, acetoxy, ketone and conjugated polyene units.
Yui Wakasa, Mao Minoura
wiley   +1 more source

Limited capacity for rapid acclimation to marine heatwaves in coastal invertebrates

Journal of Animal Ecology, EarlyView.
Across 10 coastal invertebrate species, we provide a rare multi‐species test of rapid acclimation to realistic marine heatwaves. Responses are consistently weak, revealing that short‐term plasticity cannot keep pace with warming and may lead to underestimated vulnerability in coastal ecosystems. Abstract Marine heatwaves are increasing in frequency and
Mafalda Tomás, Patrice Pottier, Alexandro Autiero, Elena Tamarit‐Castro, Alex A. Berry, Tamzin A. Blewett, Ivan Cadonic, Dustin Doty, Maryane Gradito, Elizabeth C. Hoots, Luis L. Kuchenmüller, Sidney Martin, Vincent Mélançon, Juliane Vigneault, Timothy D. Clark, Zara‐Louise Cowan, Fredrik Jutfelt, Leon Green   +17 more
wiley   +1 more source

Taxonomic and functional diversity of noctuoid moths in a Mediterranean coastal area: implications for dune conservation in a long‐term ecological research eLTER site

Insect Science, EarlyView.
This study investigates the taxonomic and functional diversity of noctuoid moths in a protected coastal dune system in Central Italy, revealing strong ecological associations between moth assemblages and dune zonation. Differences in species composition and trait attributes, along with the presence of habitat‐exclusive species, highlight the role of ...
Micaela del Valle Rasino, Simone Fattorini, Michele Innangi, Angela Stanisci, Andrea Sciarretta, Maria Laura Carranza   +5 more
wiley   +1 more source

Drivers of Mouse Plagues: Exceptional Rainfall Following Prolonged Drought Triggers Mouse Plagues in Southeastern Australia

Integrative Zoology, EarlyView.
This study identified a specific sequence of an extended drought followed by exceptional rainfall as a necessary precursor for mouse plagues in southeastern Australia. Long‐term rainfall anomalies interact with ecological processes to reset population dynamics, creating conditions that support rapid mouse population growth following periods of ...
Peter R. Brown
wiley   +1 more source

Sperm Head–Tail Coupling Apparatus Diversity and Common Themes Among Species

Andrology, EarlyView.
ABSTRACT Background A stable connection between the sperm head (containing the nucleus and acrosome) and tail (containing the axoneme, mitochondrial sheath, and periaxonemal structures) is critical for fertility. This connection is mediated by a series of nuclear, cytoplasmic, and centriole components that make up the head–tail coupling apparatus (HTCA)
Danielle B. Buglak, Brian J. Galletta, Nasser M. Rusan   +2 more
wiley   +1 more source

Response of Remote Tropical West Pacific Islands to Climate Variability: A Multiproxy Record From T‐Lake, Palau, Spanning the Early Holocene to Present

Archaeometry, EarlyView.
ABSTRACT Lake sediments are natural archives of past environmental dynamics and how these systems have responded to past climate variability. Sediment geochemistry, governed by local geology and climate processes, is unique to each lake‐catchment and geochemical proxies must be validated for each study site.
Jalene Nalbant, Larissa Schneider, Jessica L. Blois, Matthew Wolhowe, Julian P. Sachs, Simon G. Haberle, Geoffrey Clark   +6 more
wiley   +1 more source