Results 91 to 100 of about 56,629 (301)
Men on horseback at Big Bear Farms
, 1962 Black and white photograph of Big Bear stores President, Wayne E. Brown, at Big Bear Farms in Powell, Ohio. In 1934, an innovation in food retailing was introduced in Columbus when Wayne E. Brown opened the first self-service supermarket in central Ohio.
Big Bear
core
ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells
Advanced Science, EarlyView.With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao +16 more
wiley +1 more source
Brown bear in the legal system of the Slovak Republic – monitoring, protection, responsibility
Prawne Problemy Górnictwa i Ochrony ŚrodowiskaThe brown bear (Ursus arctos) is a protected animal species under Act No. 543/2002 Coll. on Nature and Landscape Protection. The level of protection of this species directly affects the existence of state liability for damage caused by its activity.
Jana Šmelková, Martin Dufala
doaj +1 more source
Zanesville Big Bear canned goods
, 1948 Canned goods at Zanesville Big Bear location, in June of 1948. Big Bear is responsible for many innovations in the supermarket business. They were the first to introduce motorized counters that were controlled by the cashier. Unique store layouts placing
Big Bear
core
In Vivo Microplastic Detection With Photoacoustic Imaging
Advanced Science, EarlyView.ABSTRACT Microplastics are posing an escalating threat to both ecological systems and human health. Yet, current methods for investigating their bioaccumulation are highly invasive, requiring destructive analysis of ex vivo tissues via mass spectrometry, dye labelling, or Raman microspectroscopy.
Joseph C. Bear +9 more
wiley +1 more source
Zanesville Big Bear store interior
, 1948 Canned goods at Zanesville Big Bear location, in June of 1948. Big Bear is responsible for many innovations in the supermarket business. They were the first to introduce motorized counters that were controlled by the cashier. Unique store layouts placing
Big Bear
core
Advanced Science, EarlyView.A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang +19 more
wiley +1 more source
BMC Veterinary Research, 2019 Background Mycobacterium bovis is known to have a wide host range and has been isolated from numerous free-ranging wildlife species, carnivores included. In bears, M. bovis has been previously reported only from a culture of pooled lymph nodes of a black
Rosario Fico +6 more
doaj +1 more source
1958 illuminated Big Bear billboard
, 1958 Illuminated Big Bear billboard from 1958. The billboard reads, " Big Bear. Always convenient parking! Columbus most modern super markets." In 1934, an innovation in food retailing was introduced in Columbus when Wayne E.
Big Bear
core
Advanced Science, EarlyView.ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung +19 more
wiley +1 more source