Forty Years of the Description of Brown Spider Venom Phospholipases-D [PDF]
Toxins, 2020 Spiders of the genus Loxosceles, popularly known as Brown spiders, are considered a serious public health issue, especially in regions of hot or temperate climates, such as parts of North and South America.
Luiza Helena Gremski +9 more
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Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates [PDF]
Toxins, 2023 Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade ...
Daniele Chaves-Moreira +9 more
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Highlights in the knowledge of brown spider toxins [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2017 Brown spiders are venomous arthropods that use their venom for predation and defense. In humans, bites of these animals provoke injuries including dermonecrosis with gravitational spread of lesions, hematological abnormalities and impaired renal function.
Daniele Chaves-Moreira +5 more
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Brown Spider (Loxosceles) Venom Toxins as Potential Biotools for the Development of Novel Therapeutics [PDF]
Toxins, 2019 Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological disturbances. Several toxins make
Daniele Chaves-Moreira +11 more
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TCTP from Loxosceles Intermedia (Brown Spider) Venom Contributes to the Allergic and Inflammatory Response of Cutaneous Loxoscelism [PDF]
Cells, 2019 LiTCTP is a toxin from the Translationally Controlled Tumor Protein (TCTP) family identified in Loxosceles brown spider venoms. These proteins are known as histamine-releasing factors (HRF). TCTPs participate in allergic and anaphylactic reactions, which
Marianna Boia-Ferreira +12 more
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Clinical Spectrum of Hemolytic Anemia in Loxoscelism: Report of Two Cases Highlighting Variable Severity and Management [PDF]
Case Reports in HematologyLoxoscelism can cause local as well as systemic manifestations. Hematologic complications of brown recluse spider venom can be life-threatening.
Anas Al-Sadi +4 more
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Brown Recluse Spider Bites [PDF]
The Journal of the American Board of Family Medicine, 2000 Brown recluse spider bites are a serious medical problem in the southeastern United States. Although most bites are asymptomatic, envenomation can result in a constellation of systemic symptoms referred to as loxoscelism. Patients can also develop necrotic skin ulcers (necrotic arachnidism). These ulcers are often difficult to heal and can require skin
H H, Sams, L E, King
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Brown Recluse spider bite mediated hemolysis: clinical features, a possible role for complement inhibitor therapy, and reduced RBC surface glycophorin A as a potential biomarker of venom exposure. [PDF]
PLoS ONE, 2013 The venom of Loxosceles reclusa (Brown Recluse spider) can cause a severe, life-threatening hemolysis in humans for which no therapy is currently available in the USA beyond supportive measures.
Eric A Gehrie, Hui Nian, Pampee P Young
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Brown Recluse Spider, Loxosceles reclusa Gertsch and Mulaik (Arachnida: Araneae: Sicariidae)
EDIS, 2005 The brown recluse spider, Loxosceles reclusa Gertsch & Mulaik, is frequently reported in Florida as a cause of necrotic lesions in humans. For example, in the year 2000 alone, Loft (2001) reported that the Florida Poison Control Network had recorded ...
Glavis B. Edwards, Jr.
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Preparation and validation of a systemic loxoscelism prediction protocol
Revista de la Facultad de Medicina Humana, 2020 Introduction: Systemic loxoscelism is the most severe complication of loxoscelism. The management of the cadre by health personnel presents a high variability due to factors that are currently unknown.
Rafael Pichardo-Rodriguez +3 more
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