Results 161 to 170 of about 4,349,521 (358)

Acromegaly: pathogenesis & treatment [PDF]

, 2019
Acromegaly is a multi-system disorder whose etiology is most often traced back to a growth hormone-secreting pituitary adenoma (PA). Growth hormone (GH) secretion promotes insulin-like growth factor 1 (IGF-1) release from peripheral tissues, leading to ...
Tilvawala, Megha
core  

Brown tumor of the maxillary sinus in a patient with primary hyperparathyroidism: a case report [PDF]

, 2009
Efklidis Proimos, Theognosia S. Chimona, D Tamiolakis, Michalis G Tzanakakis, Chariton E. Papadakis   +4 more
openalex   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

A Brown Tumor Simulating Bone Metastases

Case Reports in Clinical Practice, 2016
Primary hyperparathyroidism usually presents with renal, gastrointestinal, mental and skeletal signs and symptoms. Brown tumor is a benign lesion that arises as a direct result of parathyroid hormone on bone tissue in some patients with ...
Neda Naderi, Azam Alamdari, Maryam Edalatifard, Seyyed Farshad Allameh   +3 more
doaj  

Brown tumor due to primary hyperparathyroidism in a familial case: a case report. [PDF]

BMC Endocr Disord, 2023
Diao Z, Zhang J, Zhao J, Sun W, Pu Z.
europepmc   +1 more source

Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma [PDF]

, 2010
Karolin H. Nord, Linda Magnusson, Margareth Isaksson, Jenny Nilsson, Henrik Lilljebjörn, Henryk A. Domanski, Lars‐Gunnar Kindblom, Nils Mandahl, Fredrik Mertens   +8 more
openalex   +1 more source

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy

Advanced Science, EarlyView.
This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang, Wengui Lu, Zhifei Cheng, Luyao Wang, Zhenzhen Jiang, Yike Yue, Pengyu Jiang, Zehua Xia, Lei He, Fengying Wang, Limin Wu, Qi Wang, Hui Han   +12 more
wiley   +1 more source

Brown tumor diagnosed three years after parathyroidectomy in a patient with nail-patella syndrome: A case report

Bone Reports, 2019
We report a 48-year-old Japanese man with a brown tumor of the right distal tibia. At the age of 25 years, hemodialysis was initiated due to nail-patella syndrome.
Naoya Toriu, Toshiharu Ueno, Hiroki Mizuno, Akinari Sekine, Noriko Hayami, Rikako Hiramatsu, Keiichi Sumida, Masayuki Yamanouchi, Eiko Hasegawa, Tatsuya Suwabe, Junichi Hoshino, Naoki Sawa, Kenmei Takaichi, Takeshi Fujii, Tomoka Hasegawa, Norio Amizuka, Motoko Yanagita, Yoshifumi Ubara   +17 more
doaj  

Emerging Nanotechnology Strategies for Obesity Therapy

Advanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang, Zhaoxu Meng, Yuezhu Zhao, Yake Qi, Zhou Li, He Lian   +5 more
wiley   +1 more source

A Framework for Assessing the Rationality of Judgments in Carcinogenicity Hazard Identification [PDF]

, 1997
Arguing that guidelines for identifying carcinogens now lack a philosophically rigorous framework, the authors present an alternative that draws clear attention to the process of reasoning towards judgments of ...
Brown, Kenneth G., Crawford-Brown, Douglas J.   +1 more
core   +2 more sources