Results 31 to 40 of about 2,934,590 (273)
Giant Cell Reparative Granuloma (G.C.R.G) of the Maxillary Sinus (Brown Tumor): a Case Report and Review of Literature [PDF]
Journal of Kerman University of Medical Sciences, 2005 The patient is a seventheen years old girl, with severe pain and swelling in right maxillary sinus region and facial deformity from two weeks prior to referring.
K Mozafarinia
doaj
OSSEOUS AND DENTAL PROBLEMS IN PATIENTS WITH RENAL FAILURE [PDF]
Journal of IMAB, 2010 We present a case of a patient with severe renal disease and many complications. The patient is fully questioned and tested due to the searched dental focus - his state is not going better in spite of the treatment and the partial parathyroidectomy.
Miglena Balcheva +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Severe Sporadic Primary Hyperparathyroidism Masquerading as Hyperparathyroidism Jaw Tumor Syndrome
Clinical Case ReportsJaw lesions are rare in Primary hyperparathyroidism (PHPT) and often mimic odontogenic tumors or syndromic conditions such as hyperparathyroidism Jaw Tumor (HPT‐JT) syndrome.
Brook Alemayehu Tesfaye +4 more
doaj +1 more source
Multiple brown tumors in primary hyperparathyroidism
Radiology Case Reports, 2022 Brown tumors are benign bone tumors that rarely complicate hyperparathyroidism, manifesting as fibrous and erosive lesions secondary to rapid and localized osteoclast turnover. These lesions are typical of primary hyperparathyroidism, but they are not often observed.
Chirihan Ayadi +7 more
openaire +3 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Bone Reports, 2021 Brown tumors are osteolytic lesions associated with hyperparathyroidism (HPT). They may involve various skeletal segments, but rarely the cranio-facial bones.
Davide Diacinti +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source