Results 111 to 120 of about 1,538,874 (331)

Digital Bioassays on the Slipchip Microfluidic Devices

open access: yesAdvanced Sensor Research, EarlyView.
This review summarizes recent advances in SlipChip‐based digital bioassays, highlighting their simple “load and slip” operation for fluid partitioning which eliminate the need for sophisticated fluidic systems. Applications include digital nucleic acid analysis, digital protein analysis and single‐cell analysis, demonstrating the platform‘s potential ...
Qingqing Luo   +5 more
wiley   +1 more source

Physics of Selective Targeting of Cancer Cells by Magnetoelectric Nanoparticles: Exploring the Role of Conductivity and Capacitance in Tumor‐Specific Attraction

open access: yesAdvanced Theory and Simulations, EarlyView.
Magnetoelectric nanoparticles exploit cancer cells' electrical vulnerabilities—altered membrane charge and higher capacitance—to achieve tumor‐specific targeting without bioreagents. MATLAB simulations reveal how electromagnetic forces create targeting specificity, while external magnetic fields enhance precision. This may enable wirelessly controlled,
Max Shotbolt   +3 more
wiley   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

open access: yesAdvanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi   +16 more
wiley   +1 more source

Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model

open access: yesAdvanced Science, EarlyView.
A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.
Marco Andreana   +10 more
wiley   +1 more source

Brownian motion in biological membranes.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1975
Brownian motion (diffusion) of particles in membranes occurs in a highly anisotropic environment. For such particles a translational mobility (independent of velocity) can be defined if the viscosity of the liquid embedding the membrane is taken into ...
P. Saffman, M. Delbrück
semanticscholar   +1 more source

Small values and functional laws of the iterated logarithm for operator fractional Brownian motion

open access: yesOpen Mathematics
The multivariate Gaussian random fields with matrix-based scaling laws are widely used for inference in statistics and many applied areas. In such contexts, interests are often Hölder regularities of spatial surfaces in any given direction.
Wang Wensheng, Dong Jingshuang
doaj   +1 more source

Designing Tunable DNA Condensates to Control Membrane Budding Transformation in Synthetic Cells

open access: yesAdvanced Science, EarlyView.
In giant unilamellar vesicles (GUVs), membrane wetting of encapsulated liquid‐liquid phase‐separated DNA condensates can be precisely triggered post‐fabrication using photoactivatable DNA‐lipid linkers. On free‐standing membranes, interactions between DNA condensates and the membrane lead to outward budding, resembling exocytosis.
Nastasja Kaletta   +3 more
wiley   +1 more source

Ultrasound‐Induced Nitric Oxide‐Propelled Nanomotor for Multimodal Theranostics of Cancer with Deep Penetration and Extended Lifetime

open access: yesAdvanced Science, EarlyView.
A hollow nanomotor (PM‐HMSN/Arg) propelled by ultrasound‐triggered nitric oxide (NO) was developed. The nanomotor employs a “tethering‐relaxing‐drilling” mechanism to overcome biological barriers, enabling multimodal theranostics of cancer with deep penetration and extended lifetime.
Xue Xu   +7 more
wiley   +1 more source

Stochastic Current of Bifractional Brownian Motion

open access: yesJournal of Applied Mathematics, 2014
We study the regularity of stochastic current defined as Skorohod integral with respect to bifractional Brownian motion through Malliavin calculus. Moreover, we similarly derive some results in the case of multidimensional multiparameter.
Jingjun Guo
doaj   +1 more source

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