Results 121 to 130 of about 2,265 (166)

Immune responses to bovine respiratory syncytial virus (BRSV) following use of an inactivated BRSV-PI3-Mannheimia haemolytica vaccine and a modified live BRSV–BVDV vaccine

Veterinary Journal, 2004
P Kerkhofs
exaly   +3 more sources

Generation of Bovine Respiratory Syncytial Virus (BRSV) from cDNA: BRSV NS2 Is Not Essential for Virus Replication in Tissue Culture, and the Human RSV Leader Region Acts as a Functional BRSV Genome Promoter [PDF]

Journal of Virology, 1999
ABSTRACT In order to generate recombinant bovine respiratory syncytial virus (BRSV), the genome of BRSV strain A51908, variant ATue51908, was cloned as cDNA. We provide here the sequence of the BRSV genome ends and of the entire L gene. This completes the sequence of the BRSV genome, which comprises a total of 15,140 nucleotides.
Stefan Finke, Ursula Buchholz, Karl-Klaus Conzelmann   +2 more
exaly   +3 more sources

Interferon gamma production during bovine respiratory syncytial virus (BRSV) infection is diminished in calves vaccinated with formalin-inactivated BRSV

Vaccine, 1999
Formalin-inactivated respiratory syncytial virus (FI-RSV) vaccination has been associated with severe disease in humans. Research in mice suggests that FI-RSV may prime for decreased interferon gamma (IFN-gamma) production at subsequent infection. Interferon-gamma production by peripheral blood mononuclear cells (PBMC) was measured following challenge ...
Amelia Woolums, Laurel Gershwin
exaly   +3 more sources

Demonstration of Protection Provided by a Single Dose Modified Live BRSV Vaccine against Virulent BRSV Challenge

American Association of Bovine Practitioners Conference Proceedings, 2020
Bovine respiratory syncytial virus (BRSV) is an economically important cause of respiratory disease in cattle worldwide. The virus is an important respiratory pathogen in naïve cattle of all ages, but as with other respiratory syncytial viruses, it primarily affects young calves. The virus has also been implicated as one of the viral agents involved in
Ellis, J., West, K. H., Ohnesorge, W. C., Rinehart, C. L.   +3 more
openaire   +1 more source

Immunization with a peptide derived from the G glycoprotein of bovine respiratory syncytial virus (BRSV) reduces the incidence of BRSV-associated pneumonia in the natural host

Vaccine, 1997
Previous reports demonstrate that synthetic peptides corresponding to the amino acid region 174-187 of G glycoprotein from subgroups A and B human respiratory syncytial virus (HRSV), containing a Cys-->Ser substitution at position 186, confer complete resistance to immunized BALB/c mice against infection with the respective virus.
C Simard, Michel Trudel, M Trudel
exaly   +3 more sources

Resistance to bovine respiratory syncytial virus (BRSV) induced in calves by a recombinant bovine herpesvirus-1 expressing the attachment glycoprotein of BRSV.

Journal of General Virology, 1998
The ability of a bovine herpesvirus-1 (BHV-1) recombinant expressing the G protein of bovine respiratory syncytial virus (BRSV) to protect against BRSV infection was examined in calves. A synthetic G gene was inserted behind the gE promoter of BHV-1 to give a gE-negative, BHV-1/G recombinant.
J T Van Oirschot, W I Morrison, F A M Rijsewijk   +2 more
exaly   +3 more sources

Efficacy of an Inactivated BRSV Vaccine Against a Virulent BRSV Experimental Challenge in Young Calves

American Association of Bovine Practitioners Conference Proceedings, 2000
The objective of this study was to determine the efficacy of a vaccine containing inactivated Bovine Respiratory Syncytial Virus (BRSV) against a highly virulent BRSV challenge in calves.
Ellis, J., West, K. H., Gallo, G., Conlon, J. Rice   +3 more
openaire   +1 more source

Vaccination of calves using the BRSV nucleocapsid protein in a DNA prime–protein boost strategy stimulates cell-mediated immunity and protects the lungs against BRSV replication and pathology

Vaccine, 2008
Respiratory syncytial virus (RSV) is a major cause of respiratory disease in both cattle and young children. Despite the development of vaccines against bovine (B)RSV, incomplete protection and exacerbation of subsequent RSV disease have occurred. In order to circumvent these problems, calves were vaccinated with the nucleocapsid protein, known to be a
Gilles Meyer, Jean-François Toussaint, Jean-Jacques Letesson   +2 more
exaly   +5 more sources

Comparison of DNA application methods to reduce BRSV shedding in cattle

Vaccine, 1998
We compared the protection afforded by three different DNA application methods against bovine respiratory syncytial virus (BRSV) infection in cattle. A synthetic gene that codes for the G protein of BRSV was inserted into a eukaryotic vector and was used in the vaccine. Intradermal (i.d.) application with a needleless injector (NI), the Pigjet, reduced
Schrijver, R.S., Langedijk, J.P.M., Keil, G.M., Middel, W.G.J., Maris-Veldhuis, M., van Oirschot, J.T., Rijsewijk, F.A.M.   +6 more
openaire   +3 more sources