Expression of Brucella abortus Omp25 Protein in Lactococcus lactis Probiotic Bacteria [PDF]
Background and purpose: The sequence of Omp25 is conserved in all Brucella species. The high antigenicity of the product of this gene stimulates the host’s immune system. Using engineered probiotic bacteria is an appropriate method for vaccine transport.
Somayeh Tirbakhsh Gouran +2 more
doaj
From Culture to Sequencing: Evolving Strategies for the Diagnosis of Pediatric Spondylodiscitis
Diagnostic approaches to pediatric spondylodiscitis have evolved from culture‐based methods with limited sensitivity to advanced molecular and sequencing technologies. Metagenomic next‐generation sequencing (mNGS) enables rapid, culture‐independent pathogen identification, improving diagnostic accuracy, guiding therapy, and reducing invasive procedures
Viola Sbampato +4 more
wiley +1 more source
Marker Loci in Brucella Genome for Differential PCR Indication of Pathogenic strains
Objective of this work was to develop the algorithms for differential PCR indication of Brucella genus strains using databases of their genomes. Materials and methods .Resources of the National Center for Biotechnology Information (NCBI) and BLAST and ...
N. I. Khammadov +5 more
doaj +1 more source
The small protein CydX is required for function of cytochrome bd oxidase in Brucella abortus. [PDF]
A large number of hypothetical genes potentially encoding small proteins of unknown function are annotated in the Brucella abortus genome. Individual deletion of 30 of these genes identified four mutants, in BAB1_0355, BAB2_0726, BAB2_0470, and BAB2_0450
de Jong, Maarten F +5 more
core +3 more sources
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva +8 more
wiley +1 more source
Brucellosis in the Head and Neck: A Forgotten Differential Diagnosis
INTRODUCTION: Patients with brucellosis present with nonspecific symptoms originating from different organs. In this study, we aimed to investigate the symptoms related to the head and neck region in patients with brucellosis. METHODS: The retrospective
Yaser Said Çetin, İlyas Dündar
doaj +1 more source
Preparation of Hyperimmune Sera to Thermoextracts of Brucella S- and L-Forms
Objective of the study was to prepare hyperimmune sera to Brucella S- and L-form thermo-extracts. Materials and methods. Thermo-extracts from Brucella abortus I-206 strain in S- and L-forms were used.
L. M. Мikhailov +6 more
doaj +1 more source
Btp Proteins from Brucella abortus Modulate the Lung Innate Immune Response to Infection by the Respiratory Route [PDF]
Although inhalation of infected aerosols is a frequent route for Brucella infection in humans, it rarely causes pulmonary clinical manifestations, suggesting a mild or nearly absent local inflammatory response.
Baldi, Pablo Cesar +6 more
core +1 more source
ABSTRACT Introduction This study explored transmission patterns of brucellosis in Hubei Province, a Class II region in China, through analysis of spatiotemporal distribution and environmental factors to provide evidence for precise prevention. Methods We analysed epidemiological data from Hubei Province (2010–2023), including human cases, demographics,
Qi Chen +7 more
wiley +1 more source
A lysozyme-like protein in Brucella abortus is involved in the early stages of intracellular replication [PDF]
Secretion of proteins in Gram-negative bacteria is a high-energy consuming process that requires the translocation across two membranes and a periplasmic space composed of a mesh like layer, the peptidoglycan.
Czibener, Cecilia +2 more
core +1 more source

