Results 81 to 90 of about 87,209 (269)

Serological and molecular detection of bovine brucellosis at institutional livestock farms in Punjab, Pakistan [PDF]

open access: yes, 2020
Bovine brucellosis remains a persistent infection in ruminants in Pakistan. A total of 828 (409 buffaloes and 419 cattle) sera were collected from 11 institutional-owned livestock farms in Punjab, Pakistan.
Hussain, Muhammad Hammad   +9 more
core   +1 more source

An HWE‐Family Histidine Kinase Modulates Brucella Cell Envelope Properties and Host Innate Immune Response

open access: yesMolecular Microbiology, EarlyView.
The HWE‐family histidine kinase PhyK regulates the cell envelope structure of the intracellular pathogen Brucella ovis and affects how the host immune system responds to this bacterium. Deletion of phyK alters bacterial survival in the face of detergent stress and reduces immune activation in infected macrophages.
Xingru Chen   +6 more
wiley   +1 more source

The glutaminase-dependent acid resistance system. Qualitative and quantitative assays and analysis of its distribution in enteric bacteria [PDF]

open access: yes, 2018
Neutralophilic bacteria have developed several strategies to overcome the deleterious effects of acid stress. In particular, the amino acid-dependent systems are widespread, with their activities overlapping, covering a rather large pH range, from 6 to
DE BIASE, Daniela   +4 more
core   +13 more sources

A century of assessment: A systematic review of biothreat risk assessments

open access: yesRisk Analysis, EarlyView.
Abstract Throughout the past century, assessments of the risks and benefits posed by high‐consequence biological agents have guided US decision‐making on weapons research, countermeasure development, and security policy. However, the dispersed nature of these biothreat risk assessments has presented various difficulties, such as duplicative effort ...
Claire Atkerson, Michael T Parker
wiley   +1 more source

New Scenarios for Brucella suis and Brucella melitensis

open access: yesCurrent Clinical Microbiology Reports, 2017
We pretend to highlight the most important advances reached in the last few years in the biology of Brucella suis and Brucella melitensis and focus attention on new tools for the comprehension, prevention and control of these zoonotic agents. Important progress lately done in the field of pathogenesis is presented here. This involves current studies on
Samartino, Luis   +2 more
openaire   +3 more sources

Genomics reveals historic and contemporary transmission dynamics of a bacterial disease among wildlife and livestock [PDF]

open access: yes, 2016
Whole-genome sequencing has provided fundamental insights into infectious disease epidemiology, but has rarely been used for examining transmission dynamics of a bacterial pathogen in wildlife.
Anderson, Neil J.   +15 more
core   +2 more sources

The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review

open access: yesZoonoses and Public Health, EarlyView.
ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans, in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs   +6 more
wiley   +1 more source

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin‐Independent Regulation of Fpn mRNA

open access: yesAmerican Journal of Hematology, Volume 100, Issue 8, Page 1323-1333, August 2025.
ABSTRACT The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) by inhibiting the iron exporter ferroportin in target cells, causing hypoferremia. Under acute inflammation, hepcidin induction requires hemojuvelin (Hjv), a bone morphogenetic protein co‐receptor, while Fpn mRNA is also suppressed in a hepcidin‐
Siqi Liu   +3 more
wiley   +1 more source

Genetic and Phenotypic Characterization of the Etiological Agent of Canine Orchiepididymitis Smooth Brucella sp. BCCN84.3

open access: yesFrontiers in Veterinary Science, 2019
Members of the genus Brucella cluster in two phylogenetic groups: classical and non-classical species. The former group is composed of Brucella species that cause disease in mammals, including humans. A Brucella species, labeled as Brucella sp. BCCN84.3,
Caterina Guzmán-Verri   +18 more
doaj   +1 more source

Structural Insights into the HWE Histidine Kinase Family: The Brucella Blue Light-Activated Histidine Kinase Domain [PDF]

open access: yes, 2016
In response to light, as part of a two-component system, the Brucella blue light-activated histidine kinase (LOV-HK) increases its autophosphorylation, modulating the virulence of this microorganism.
Arrar, Mehrnoosh   +9 more
core   +1 more source

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