Antimicrobial susceptibility of Brucella melitensis in Kazakhstan [PDF]
Antimicrobial Resistance and Infection Control, 2017 Background Kazakhstan belongs to countries with a high level of brucellosis among humans and farm animals. Although antibiotic therapy is the main way to treat acute brucellosis in humans there is still little information on a circulation of the ...
Alexandr Shevtsov +7 more
doaj +5 more sources
Whole Genome Sequence Analysis of Brucella melitensis Phylogeny and Virulence Factors
Microbiology Research, 2021 Brucellosis has a wide range of clinical severity in humans that remains poorly understood. Whole genome sequencing (WGS) analysis may be able to detect variation in virulence genes. We used Brucella melitensis sequences in the NCBI Sequence Read Archive
Peter Rabinowitz +13 more
doaj +2 more sources
BMC Veterinary Research, 2022 Background Azerbaijan currently ranks thirteenth in global incidence of human brucellosis, with an estimated annual incidence through 2000 at over 50 cases per million.
Jeyhun Aliyev +6 more
doaj +2 more sources
Molecular detection, seasonality, epidemiology and effect of Brucella melitensis infection on the hematological profile of cattle breeds [PDF]
Scientific ReportsBrucellosis is a bacterial zoonosis caused by various Brucella species, affecting both animals and humans. The incidence is particularly high in tropical and subtropical regions that are known for higher tick density.
Babar Ali +12 more
doaj +2 more sources
Metabolomic analysis of murine tissues infected with Brucella melitensis. [PDF]
PLoS ONEBrucella is a gram negative, facultative intracellular bacterial pathogen that constitutes a substantial threat to human and animal health. Brucella can replicate in a variety of tissues and can induce immune responses that alter host metabolite ...
Bárbara Ponzilacqua-Silva +4 more
doaj +2 more sources
BMC Microbiology, 2019 Background Infection with Brucella melitensis (B. melitensis) is one of the most important causes of abortion in goats and sheep, and also causes severe systemic disease in exposed humans. In Ethiopia, based on seroepidemiological studies, brucellosis is
Muluken Tekle +4 more
doaj +2 more sources
Assessment of brucellosis-causing pathogens with an emphasis on the prevalence of in the Republic of Korea: insights from a decade of pathogen surveillance (2014–2023), a retrospective study [PDF]
Osong Public Health and Research PerspectivesObjectives The main Brucella species causing human infections in the Republic of Korea is Brucella abortus, which uses cattle as its host. However, since 2014, Brucella melitensis, which uses sheep and goats as hosts, has also been identified. This study
In-Sook Shin +4 more
doaj +2 more sources
Immune response strategies of Brucella melitensis and their antigens in rats [PDF]
Iraqi Journal of Veterinary Sciences, 2022 Brucella melitensis is an intracellular bacterium and is the main brucella species that cause abortion and placenta retention in sheep and goats. It has many mechanisms to evade the immune response.
Basher S. Noomi +3 more
doaj +1 more source
Proteome-Wide Screening of Potential Vaccine Targets against Brucella melitensis
Vaccines, 2023 The ongoing antibiotic-resistance crisis is becoming a global problem affecting public health. Urgent efforts are required to design novel therapeutics against pathogenic bacterial species.
Mahnoor Malik +10 more
semanticscholar +1 more source
Design of a multi-epitope vaccine candidate against Brucella melitensis
Scientific Reports, 2022 Brucella is a typical facultative intracellular bacterium that can cause zoonotic infections. For Brucella, it is difficult to eliminate with current medical treatment.
Min Li +9 more
semanticscholar +1 more source