Integrating serological and genetic data to quantify cross-species transmission: brucellosis as a case study [PDF]
Epidemiological data are often fragmented, partial, and/or ambiguous and unable to yield the desired level of understanding of infectious disease dynamics to adequately inform control measures.
Buza, Joram J.+8 more
core +2 more sources
Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development. [PDF]
Brucella spp., are Gram negative bacteria that cause disease by growing within monocyte/macrophage lineage cells. Clinical manifestations of brucellosis are immune mediated, not due to bacterial virulence factors.
Alessandro eSette+8 more
core +1 more source
Antimicrobial susceptibility of Brucella melitensis in Kazakhstan [PDF]
Kazakhstan belongs to countries with a high level of brucellosis among humans and farm animals. Although antibiotic therapy is the main way to treat acute brucellosis in humans there is still little information on a circulation of the antibiotic-resistant Brucella strains in the Central Eurasia.
Alexandr Shevtsov+7 more
openaire +4 more sources
Serological and Molecular Identification of Brucella spp. in Pigs from Cairo and Giza Governorates, Egypt [PDF]
Brucellosis is considered as endemic disease of animals and humans since thousands of years in Egypt. However, brucellosis in pigs has never been reported in Egypt.
El-Adawy, Hosny+8 more
core +1 more source
The aggregation of Brucella abortus occurs under microaerobic conditions and promotes desiccation tolerance and biofilm formation [PDF]
Brucella abortus causes brucellosis mainly in cattle. The infection is transmitted to humans by ingestion of animal products or direct contact with infected material.
Almiron, Marta A.+2 more
core +1 more source
Simultaneous immunization with Omp25 and L7/L12 provides protection against brucellosis in mice [PDF]
Currently ...
Aggarwal, Somya+4 more
core +2 more sources
Ex vivo innate immune cytokine signature of enhanced risk of relapsing brucellosis. [PDF]
BackgroundBrucellosis, a zoonotic infection caused by one of the Gram-negative intracellular bacteria of the Brucella genus, is an ongoing public health problem in Perú.
Feldman, Kristyn E+9 more
core +3 more sources
Serological and molecular detection of bovine brucellosis at institutional livestock farms in Punjab, Pakistan [PDF]
Bovine brucellosis remains a persistent infection in ruminants in Pakistan. A total of 828 (409 buffaloes and 419 cattle) sera were collected from 11 institutional-owned livestock farms in Punjab, Pakistan.
Hussain, Muhammad Hammad+9 more
core +1 more source
Recovery of a medieval Brucella melitensis genome using shotgun metagenomics [PDF]
Shotgun metagenomics provides a powerful assumption-free approach to the recovery of pathogen genomes from contemporary and historical material. We sequenced the metagenome of a calcified nodule from the skeleton of a 14th-century middle-aged male ...
Bandiera, Pasquale+7 more
core +5 more sources
The Glutaminase-dependent system confers extreme acid resistance to new species and atypical strains of Brucella [PDF]
Neutralophilic bacteria have developed specific mechanisms to cope with the acid stress encountered in environments such as soil, fermented foods, and host compartments. In Escherichia coli, the glutamate decarboxylase (Gad)-dependent system is extremely
Al Dahouk, Sascha+7 more
core +3 more sources