Results 51 to 60 of about 19,523 (255)

Ultrasensitive and highly specific detection of the Brucella genus and B. melitensis by CRISPR/Cas12b‐multiple cross displacement amplification technique

Journal of Clinical Microbiology
Brucellosis is caused by members of the Brucella spp. and remains one of the world’s major zoonotic diseases. Brucella melitensis (B. melitensis) as the most contagious Brucella species cannot be ignored as an essential source of infection for ...
Sha Mao, Xinggui Yang, Yue Wang, Fengming Chen, Hai Jiang, Yi Wang, Yingqian Kang, Shijun Li   +7 more
doaj   +1 more source

Investigation of Genetic Relatedness of Brucella Strains in Countries Along the Silk Road

Frontiers in Veterinary Science, 2021
In this study, MLVA (multiple-locus variable-number tandem repeat analysis) genotype data of Brucella strains from 11 countries along the Silk Road were downloaded from the MLVAbank.
Zhiguo Liu, Chengling Wang, Kongjiao Wei, Zhongzhi Zhao, Miao Wang, Dan Li, Heng Wang, Qiang Wei, Zhenjun Li   +8 more
doaj   +1 more source

Btp Proteins from Brucella abortus Modulate the Lung Innate Immune Response to Infection by the Respiratory Route [PDF]

, 2017
Although inhalation of infected aerosols is a frequent route for Brucella infection in humans, it rarely causes pulmonary clinical manifestations, suggesting a mild or nearly absent local inflammatory response.
Baldi, Pablo Cesar, Comerci, Diego José, Falivene, Juliana, Fernandez, Andrea Giselle, Ferrero, Mariana Cristina, Hielpos, María Soledad, Vanzulli, Silvia   +6 more
core   +1 more source

In vitro susceptibility of Brucella melitensis to antibiotics [PDF]

Antimicrobial Agents and Chemotherapy, 1991
The in vitro susceptibilities of 86 recent clinical isolates of Brucella melitensis to minocycline, streptomycin, co-trimoxazole, rifampin, and six fluoroquinolones were determined. Minocycline exhibited the lowest MIC and was followed by rifampin and streptomycin. Among the quinolones, WIN 57273 and ciprofloxacin were the most active agents.
E, Rubinstein, R, Lang, B, Shasha, B, Hagar, L, Diamanstein, G, Joseph, M, Anderson, K, Harrison   +7 more
openaire   +2 more sources

BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43

Advanced Science, Volume 12, Issue 45, December 4, 2025.
This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan, Miao Han, Mengfei Zhang, Wenbo Chen, Fangde Xie, Xuan Luo, Wenping Wu, Congliang Wang, Donghui Yang, Bin Han, Haijing Zhu, Haisheng Yu, Na Li, Jinlian Hua   +13 more
wiley   +1 more source

Distribution of species and biotypes of brucella isolates obtained from sheep and cattle abortions [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
This study was carried out to evaluate Brucella spp. isolated from various tissue samples of aborted sheep and bovine fetuses sent to the laboratory of Department of Microbiology, Faculty of Veterinary Medicine, Kafkas University between 2011 and 2023 ...
Elif ÇELİK, Aliye GÜLMEZ SAĞLAM, Fatih BÜYÜK, Salih OTLU, Mitat ŞAHİN, Özgür ÇELEBİ, Mustafa Reha COŞKUN, Seda DURHAN, Eray BÜYÜK, Yaren ERSOY   +9 more
doaj   +1 more source

Recovery of a medieval Brucella melitensis genome using shotgun metagenomics [PDF]

, 2014
Shotgun metagenomics provides a powerful assumption-free approach to the recovery of pathogen genomes from contemporary and historical material. We sequenced the metagenome of a calcified nodule from the skeleton of a 14th-century middle-aged male ...
Bandiera, Pasquale, Bianucci, Raffaella, Bramanti, Barbara, Giuffra, Valentina, Kay, Gemma L., Milanese, Marco, Pallen, Mark J., Sergeant, Martin J.   +7 more
core   +5 more sources

Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu, Maryam Ebunoluwa Zakariya, Abdulmuheez Abiola Abdulkareem, Olalekan Toheeb Okewale, Muhammad Halima Idris, Halimah Oluwayemisi Olayiwola   +5 more
wiley   +1 more source

Hotspots of Bacterial Pathogen Abundance and Exposure Risk in Soils of the Contiguous United States

GeoHealth, Volume 9, Issue 12, December 2025.
Abstract Soils are reservoirs of pathogenic bacteria that cause human illness, particularly after mobilizing events such as extreme rain. Land‐use patterns (e.g., proximity to agriculture) and soil properties (e.g., moisture) are associated with abundance of individual pathogenic bacteria. However, there are major uncertainties in (a) the importance of
Emily A. Matthews, Ying‐Xian Goh, Shannon L. Hepp, Jingqiu Liao, Ryan S. D. Calder   +4 more
wiley   +1 more source

Isolation and identification of Brucella melitensis using bacteriological and molecular tools from aborted goats in the Afar region of north-eastern Ethiopia

BMC Microbiology, 2019
Background Infection with Brucella melitensis (B. melitensis) is one of the most important causes of abortion in goats and sheep, and also causes severe systemic disease in exposed humans. In Ethiopia, based on seroepidemiological studies, brucellosis is
Muluken Tekle, Mengistu Legesse, Bedaso Mammo Edao, Gobena Ameni, Gezahegne Mamo   +4 more
doaj   +1 more source