Results 91 to 100 of about 16,632 (223)

BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE

Архивъ внутренней медицины, 2016
Nowadays interest in channelopathies is growing, and developing diagnostic capabilities make Brugada syndrome much more actual problem than ever. Conception of «primary electric heart disease», which earlier was so popular, now couldn’t explain the ...
T. A. Pavlenko, O. V. Blagova
doaj   +1 more source

Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency

Epilepsia, Volume 67, Issue 7, Page 3738-3752, July 2026.
Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon, Shuyun Wang, Qinghua Liu, Chunling Chen, Alexander M. Greiner, Abigail M. Marx, Maya Shih, Jack M. Parent, Barry London, Lori L. Isom   +9 more
wiley   +1 more source

Distinct functional defect of three novel Brugada syndrome related cardiac sodium channel mutations

Journal of Biomedical Science, 2009
The Brugada syndrome is characterized by ST segment elevation in the right precodial leads V1-V3 on surface ECG accompanied by episodes of ventricular fibrillation causing syncope or even sudden death.
Juang Jyh-Ming, Liu Yen-Bin, Tsai Chia-Ti, Lin Jiunn-Lee, Chen Wen-Pin, Hsueh Chia-Hsiang, Tsao Hsuan-Ming, Su Ming-Jai, Lai Ling-Ping   +8 more
doaj   +1 more source

The Effect of Ketamine, Xylazine, and Ketamine/Xylazine Administration on SCN5A (Nav1.5) Gene Expression in Pigeons

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Voltage‐gated sodium channels, particularly Nav1.5 encoded by the SCN5A gene, play essential roles in neuronal conduction and cardiac function. Given the widespread use of anaesthetic agents such as ketamine and xylazine in animal studies, this study aimed to evaluate their effects on SCN5A gene expression in pigeon heart tissue.
Faezeh Sadat Moazzeni, Behnam Pedram, Seyed Morteza Razaghi Manesh   +2 more
wiley   +1 more source

Brugada Syndrome Phenotype Elimination by Epicardial Substrate Ablation [PDF]

, 2015
Whether Brugada syndrome (BrS) depends on functional epicardial substrates, which may be definitively eliminated by radiofrequency ablation, remains unknown. Methods and Results-Patients with BrS underwent epicardial mapping to identify areas of abnormal
Manguso F., Ciconte G., Pappone C., Santinelli V., Vicedomini G., Berruezo A., Giannelli L., Brugada J.   +7 more
core   +1 more source

Transient B cell lymphopenia revealed by KRECs newborn screening: Post‐screening referral strategies, clinical course, and follow‐up

Pediatric Allergy and Immunology, Volume 37, Issue 7, July 2026.
Isolated low KREC and B‐cell lymphopenia in newborns often resolve spontaneously. This multicenter cohort tracked these cases via telemedicine. Repeating KREC testing on a second dry blood spot (DBS) before specialist referral reduces unnecessary immunologic evaluations.
Guarnieri Valentina, Drago Enrico, Pelosi Caterina, Boscia Silvia, Schena Francesca, Traverso Monica, Aloi Concetta, Salina Alessandro, Palmeri Serena, Cassanello Michela, Maghnie Mohamad, Astorino Valeria, Lodi Lorenzo, Azzari Chiara, Volpi Stefano, Ricci Silvia   +15 more
wiley   +1 more source

Compound heterozygous mutations P336L and I1660V in the human cardiac sodium channel associated with the Brugada syndrome [PDF]

, 2006
BACKGROUND - Loss-of-function mutations in SCN5A have been associated with the Brugada syndrome. We report the first Brugada syndrome family with compound heterozygous mutations in SCN5A.
Hong, K., Antzelevitch, C., Pfeiffer, R., Hu, D., Brugada, J., Dumaine, R., Cordeiro, J.M., Orsino, A.-M., Brugada, P., Brugada, R., Barajas-Martinez, H., Wu, Y.S., Burashnikov, E.   +12 more
core   +1 more source

Kontroversi peran studi elektrofisiologi pada sindrom brugada

Majalah Kardiologi Indonesia, 2016
Sindrom Brugada adalah suatu abnormalitas sistem listrik jantung yang merupakan predisposisi terjadinya takikardia ventrikel dan hilang kesadaran. Takikardia ventrikel dapat berhenti spontan dan pasien pulih dari sinkop lalu berobat dengan keluhan sinkop,
Yoga Yuniadi
doaj   +1 more source

Fever Unmasked Brugada Syndrome in Pediatric Patient: A Case Report

Clinical Practice and Cases in Emergency Medicine, 2020
Introduction: Brugada syndrome is an arrhythmogenic disorder that is a known cause of sudden cardiac death. It is characterized by a pattern of ST segment elevation in the precordial leads on an electrocardiogram (EKG) due to a sodium channelopathy. Case
Orhay Mirzapolos, Perry Marshall, April Brill   +2 more
doaj   +1 more source

Brugada syndrome with a novel missense mutation in SCN5A gene: A case report from Bangladesh

Indian Heart Journal, 2014
Brugada syndrome is an inherited cardiac arrhythmia that follows autosomal dominant transmission and can cause sudden death. We report a case of Brugada syndrome in a 55-year-old male patient presented with recurrent palpitation, atypical chest pain and ...
Md. Zahidus Sayeed, Md. Abdus Salam, Md. Zahirul Haque, A.K.M. Monwarul Islam   +3 more
doaj   +1 more source