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Since its first description in 1992 as a new clinical entity, the Brugada syndrome has aroused great interest among physicians and basic scientists. Two consensus conferences held in 2002 and 2005 helped refine the current accepted definite diagnostic criteria for the syndrome, briefly, the characteristic ECG pattern (right bundle branch block and ...
Benito, B. +3 more
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The Brugada syndrome is a genetically determined disease caused by mutations of the cardiac sodium channel. The disease affects mainly males in their forties and causes sudden cardiac death because of polymorphic ventricular tachycardia. These patients have a structurally normal heart.
Brugada, Pedro, Brugada, J., Brugada, R.
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Brugada syndrome - Report of the second consensus conference [PDF]
Since its introduction as a clinical entity in 1992, the Brugada syndrome has progressed from being a rare disease to one that is second only to automobile accidents as a cause of death among young adults in some countries.
Shimizu, Wataru +26 more
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Brugada syndrome and p.E61X_RANGRF [PDF]
Background: Brugada syndrome is an inherited cardiac condition transmitted with an autosomal dominant pattern which can lead to sudden cardiac death from malignant ventricular arrhythmias.
Iglesias, Anna +6 more
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Brugada syndrome is a rare cardiac arrhythmia characterized by electrocardiographic right bundle branch block and persistent ST-segment elevation in the right precordial leads. It is associated with ventricular fibrillation and a high risk for sudden cardiac death, predominantly in younger males with structurally normal hearts.
Brugada, R. +4 more
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Resumo Fundamento: A síndrome de Brugada é um distúrbio arritmogênico hereditário caracterizado pela presença de características eletrocardiográficas específicas com ou sem sintomas. Os pacientes apresentam risco aumentado de morte súbita por fibrilação
Mariana Sarmento Militz +5 more
doaj +2 more sources
Integration of “Omics” Strategies for Biomarkers Discovery and for the Elucidation of Molecular Mechanisms Underlying Brugada Syndrome [PDF]
Purpose: The Brugada syndrome (BrS) is a severe inherited cardiac disorder. Given the high genetic and phenotypic heterogeneity of this disease, three different “omics” approaches are integrated in a synergic way to elucidate the molecular mechanisms ...
Oliva A. +18 more
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Brugada syndrome (BrS) is characterized by coved ST segment elevation in the right precordial lead (V1‐V3). Previous reports have described type‐1 or type‐2 Brugada ECG pattern as a Brugada phenocopy (BrP) in various clinical condition and once the ...
Pichmanil Khmao +3 more
doaj +1 more source
The Brugada syndrome demonstrates characteristic electrocardiogram features and is a significant cause of sudden death in young adults with overtly normal cardiac structure and function. The genetic basis has not yet been fully elucidated but our understanding of the causative mutations and modifiers of arrhythmic events is advancing rapidly alongside ...
Rachel Bastiaenen, Elijah R. Behr
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Proposed diagnostic criteria for the Brugada syndrome [PDF]
Wlat are the proper diagnostic cliteria to be used in identifying Brugada syndrome? A definitive answer to this question has been out ofreach and is the reason for the establishment of a special Arrhythrn:a Working Group of the European Society of ...
Towbin J.A. +29 more
core +1 more source

