ABSTRACT Atrial fibrillation (AF) is closely associated with atrial electrical and structural remodelling, yet effective drug strategies remain limited. Matrine (MAT), the active compound in Sophora flavescens, has shown anti‐AF effects, but its mechanisms are unclear.
Guoxin Zhang+11 more
wiley +1 more source
Safety, Efficacy and Evidence Base for Use of the Subcutaneous Implantable Cardioverter Defibrillator [PDF]
The trans-venous implantable cardioverter defibrillator (TV-ICD) is effective in treating life-threatening ventricular arrhythmia and reduces mortality in high-risk patients.
Adduci, Carmen+2 more
core +2 more sources
Síncope em contexto febril – caso clínico de síndrome de Brugada
Resumo: Em 1992, Brugada et Brugada descreveram pela primeira vez uma entidade, conhecida atualmente por síndrome de Brugada, associada a aumento do risco de arritmias ventriculares e morte súbita cardíaca em indivíduos sem cardiopatia estrutural.
Juliana Martins+6 more
doaj
Treatment of Anxiety and Depression in a Patient with Brugada Syndrome
Background. Brugada syndrome is rare and has been a clinically diagnosable entity since 1992. Its clinical manifestations are highly variable, and while some patients remain asymptomatic, others endure sudden cardiac death.
Jasper J. Chen, Rajbir S. Sangha
doaj +1 more source
Electrocardiographic Effects of Propofol versus Etomidate in Patients with Brugada Syndrome
Background: Brugada Syndrome is an inherited arrhythmogenic disease, characterized by the typical coved type ST-segment elevation in the right precordial leads from V1 through V3.
P. Flamée+13 more
semanticscholar +1 more source
Acquired Genotype‐Positive Long QT Syndrome After Pediatric Heart Transplantation
ABSTRACT Background Congenital long QT syndrome (LQTS) is rare but significant, as it carries a risk for ventricular arrhythmias and sudden cardiac death. Its diagnosis can be made clinically by serial ECGs, ambulatory ECG monitoring, and exercise stress testing; however, genetic testing is confirmatory in the majority of cases.
Nicholas V. Barresi+3 more
wiley +1 more source
In a case of female-to-male sex reassignment, testosterone therapy switches on an underlying Brugada
Background The Brugada syndrome, diagnosed by a typical electrocardiographic pattern, is a genetic condition characterised by an increased risk of potentially lethal ventricular arrhythmias and sudden cardiac death.
Patrizia Vivona+2 more
doaj +1 more source
JCS/JHRS 2024 Guideline Focused Update on Management of Cardiac Arrhythmias
Journal of Arrhythmia, Volume 41, Issue 3, June 2025.
Yu‐ki Iwasaki+37 more
wiley +1 more source
ABSTRACT Mitral annulus disjunction (MAD) is a rare but significant cause of ventricular arrhythmias in young patients. Timely diagnosis using cardiac magnetic resonance imaging and targeted management with catheter ablation can effectively control arrhythmias, improve patient outcomes, and prevent severe complications such as sudden cardiac death.
Mohammad Hosein Nikoo+3 more
wiley +1 more source
Clinical and molecular characterization of a cardiac ryanodine receptor founder mutation causing catecholaminergic polymorphic ventricular tachycardia [PDF]
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a difficult-to-diagnose cause of sudden cardiac death (SCD). We identified a family of 1400 individuals with multiple cases of CPVT, including 36 SCDs during youth.
Allegue, Catarina+12 more
core +2 more sources