Ventricular fibrillation is the most common mechanism of sudden unexpected cardiac death in persons with asymptomatic or symptomatic coronary artery disease. The electrophysiologic mechanisms reviewed in this article include: automaticity of pacemaker fibers, transformation of nonpacemaker into pacemaker fibers, "injury" currents and reentry.
Leonard S Dreifus, Leonard S Dreifus
exaly +4 more sources
Ventricular fibrillation and defibrillation [PDF]
Cardiac arrest in children is not often due to a disturbance in rhythm that is amenable to electrical defibrillation, contrary to the situation in adults. When a shockable rhythm is present, defibrillation using an external electric shock applied at an early stage after pre-oxygenation and chest compressions is of proven efficacy. Success at conversion
P, Jones, N, Lodé
openaire +2 more sources
The self-maintaining nature of ventricular fibrillation : contribution of L-type Ca²+ channels and Na+/Ca²+ exchange to cardiomyocyte Ca²+ overload in ventricular fibrillation : surface fluorescence study in isolated perfused rat hearts [PDF]
Approximately 40% of all deaths in Switzerland are due to cardiovascular diseases.1 An important part of these deaths happen because of life-threatening cardiac arrhythmias.
Driamov, Sergey
core +1 more source
Atrial cellular electrophysiological changes in patients with ventricular dysfunction may predispose to AF [PDF]
<b>Background:</b> Left ventricular systolic dysfunction (LVSD) is a risk factor for atrial fibrillation (AF), but the atrial cellular electrophysiological mechanisms in humans are unclear.
Marshall, G.E. +9 more
core +1 more source
Duration of heart failure and the risk of atrial fibrillation: different mechanisms at different times? [PDF]
Chronic heart failure increases the risk of atrial fibrillation (AF), with the prevalence of AF paralleling the severity of heart failure.1 Factors that underlie this increased susceptibility to AF may include electrical, structural, and neurohumoral ...
Rankin, A.C., Workman, A.J.
core +1 more source
Imaging ventricular fibrillation [PDF]
Ventricular fibrillation (VF) had been traditionally considered as a highly disorganized process of random electrical activity emanating from multiple, short-lived, reentrant electrical waves. It is the incessant breakup of wave fronts and the creation of new daughter waves (wavebreaks) that perpetuate VF. Other studies described VF as a process with a
Guy, Salama, Bum-Rak, Choi
openaire +2 more sources
The incidence and risk factors for new onset atrial fibrillation in the PROSPER study [PDF]
Aims Atrial fibrillation/flutter (AF) is the most common arrhythmia in older people. It associates with reduced exercise capacity, increased risk of stroke, and mortality. We aimed to determine retrospectively whether pravastatin reduces the incidence of
Jukema, J.W. +17 more
core +1 more source
Vulnerability to ventricular fibrillation [PDF]
One of the factors that favors the development of ventricular fibrillation is an increase in the dispersion of refractoriness. Experiments will be described in which an increase in dispersion in the recovery of excitability was determined during brief episodes of enhanced sympathetic nerve activity, known to increase the risk of fibrillation.
openaire +4 more sources
Mechanisms of termination and prevention of atrial fibrillation by drug therapy [PDF]
Atrial fibrillation (AF) is a disorder of the rhythm of electrical activation of the cardiac atria. It is the most common cardiac arrhythmia, has multiple aetiologies, and increases the risk of death from stroke.
Smith, G.L. +5 more
core +1 more source
Advances in Imaging for Atrial Fibrillation Ablation [PDF]
Over the last fifteen years, our understanding of the pathophysiology of atrial fibrillation (AF) has paved the way for ablation to be utilized as an effective treatment option.
Andrew D'Silva +3 more
core +1 more source

