Results 31 to 40 of about 164,585 (312)

Transient outward K+ current (ITO) reduction prolongs action potentials and promotes afterdepolarisations: a dynamic-clamp study in human and rabbit cardiac atrial myocytes [PDF]

, 2012
Background and aim: Human atrial transient outward K+ current (ITO) is decreased in a variety of cardiac pathologies, but how ITO reduction alters action potentials (AP) and arrhythmia mechanisms is poorly understood, owing to non-selectivity of ITO ...
Marshall, G.E., Dempster, J., Smith, G.L., Rankin, A.C., Workman, A.J.   +4 more
core   +1 more source

Explainable artificial intelligence for heart rate variability in ECG signal

Healthcare Technology Letters, 2020
Electrocardiogram (ECG) signal is one of the most reliable methods to analyse the cardiovascular system. In the literature, there are different deep learning architectures proposed to detect various types of tachycardia diseases, such as atrial ...
Sanjana K., Sowmya V., Gopalakrishnan E.A., Gopalakrishnan E.A., Soman K.P.   +4 more
doaj   +1 more source

Potential Application of Pulsed Field Ablation in Ventricular Arrhythmias

Medicina, 2023
Pulsed field ablation (PFA) is a new ablative method for the therapy of arrhythmia. Recent preclinical and clinical studies have already demonstrated the feasibility and safety of PFA for the treatment of atrial fibrillation (AF).
Jie Qiu, Meiyan Dai, Yang Bai, Guangzhi Chen   +3 more
doaj   +1 more source

The contribution of ionic currents to changes in refractoriness of human atrial myocytes associated with chronic atrial fibrillation [PDF]

, 2001
<b>Objective:</b> To investigate changes in human atrial single cell functional electrophysiological properties associated with chronic atrial fibrillation (AF), and the contribution to these of accompanying ion current changes.
K Shivkumar, Kane, K.A., Kane, Kathleen, Rankin, A.C., A Workman, Workman, A.J.   +5 more
core   +1 more source

Cathepsin A Mediates Ventricular Remote Remodeling and Atrial Cardiomyopathy in Rats With Ventricular Ischemia/Reperfusion

JACC: Basic to Translational Science, 2019
Summary: After myocardial infarction, remote ventricular remodeling and atrial cardiomyopathy progress despite successful revascularization. In a rat model of ventricular ischemia/reperfusion, pharmacological inhibition of the protease activity of ...
Mathias Hohl, PhD, Katharina Erb, Lisa Lang, Sven Ruf, PhD, Thomas Hübschle, PhD, Stefan Dhein, MD, Wolfgang Linz, PhD, Adrian D. Elliott, PhD, Prashanthan Sanders, MBBS, PhD, Olesja Zamyatkin, Michael Böhm, MD, Ulrich Schotten, MD, PhD, Thorsten Sadowski, PhD, Dominik Linz, MD, PhD   +13 more
doaj   +1 more source

Unfortunately Fortunate

JACC: Case Reports, 2020
An 88-year-old female presented with inappropriate implantable cardioverter-defibrillator shocks. Interrogation revealed lead noise sensed as ventricular fibrillation, leading to 11 shocks in 1 day. A defibrillation at the period of maximal vulnerability
Ilya V. Ryaboy, MD, Mark E. Peele, MD
doaj   +1 more source

Early Repolarization Pattern and Idiopatic Sustained Monomorphic Ventricular Tachycardia: an Infrequent Combination

Journal of Cardiac Arrhythmias, 2021
Malignant early repolarization as cause of sudden death has taken on great importance in recent years. It has been described as an entity capable of producing ventricular arrhythmic events, causing from episodes of syncope to sudden cardiac death ...
Javier Pinos Vásquez, Tiago Luiz Luz Leiria, Marcelo Lapa Kruse, Gustavo Glotz de Lima   +3 more
doaj   +4 more sources

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Electrophysiological and arrhythmogenic effects of 5-hydroxytryptamine on human atrial cells are reduced in atrial fibrillation [PDF]

, 2007
5-Hydroxytryptamine (5-HT) is proarrhythmic in atrial cells from patients in sinus rhythm (SR) via activation of 5-HT₄ receptors, but its effects in atrial cells from patients with atrial fibrillation (AF) are unknown.
Kane, K.A., Kane, Kathleen A., Rankin, A.C., Workman, Antony J., Pau, Davide, Workman, A.J., Rankin, Andrew C., Pau, D.   +7 more
core   +1 more source

Clinical Outcomes in Patients With Nonobstructive, Labile, and Obstructive Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundHypertrophic cardiomyopathy (HCM) is a common inherited cardiac disease characterized by varying degrees of left ventricular outflow tract obstruction. In a large cohort, we compare the outcomes among 3 different hemodynamic groups. Methods and
Dai‐Yin Lu, Iraklis Pozios, Bereketeab Haileselassie, Ioannis Ventoulis, Hongyun Liu, Lars L. Sorensen, Marco Canepa, Susan Phillip, M. Roselle Abraham, Theodore P. Abraham   +9 more
doaj   +1 more source