Results 11 to 20 of about 279,782 (249)

NMR_Plotter: A Python GUI for Generating Figures from NMR Spectra

open access: yesJournal of Open Research Software
NMR_Plotter is a small, purpose-built graphical plotting tool written in Python, designed to help users generate publication-quality figures from nuclear magnetic resonance (NMR) spectroscopy data.
Thomas Osborn Popp   +3 more
doaj   +1 more source

Low-Field Benchtop NMR to Discover Early-Onset Sepsis: A Proof of Concept

open access: yesMetabolites, 2023
Low-field (LF) benchtop NMR is a new family of instruments available on the market, promising for fast metabolic fingerprinting and targeted quantification of specific metabolites despite a lack of sensitivity and resolution with respect to high-field ...
Matteo Stocchero   +5 more
doaj   +1 more source

Exploring the Quantitative Performance of Small Animal PET/MRI

open access: yesJournal of Isotopes
Small animal PET/MRI is an integrated imaging device that combines the high-performance molecular imaging function of PET with the excellent soft tissue contrast function of MRI,offering unique advantages and significant application value in drug ...
Fukuan ZHAO   +7 more
doaj   +1 more source

Low-Dose Imaging in a New Preclinical Total-Body PET/CT Scanner

open access: yesFrontiers in Medicine, 2019
Ionizing radiation constitutes a health risk to imaging scientists and study animals. Both PET and CT produce ionizing radiation. CT doses in pre-clinical in vivo imaging typically range from 50 to 1,000 mGy and biological effects in mice at this dose ...
Cesar Molinos   +19 more
doaj   +1 more source

From hemolymph to in-vivo: The potential of a 1 mm microlitre flow probe with separate lock chamber for NMR metabolomics in mass limited environmental samples

open access: yesJournal of Magnetic Resonance Open, 2022
Metabolomics is one of the leading approaches for understanding the toxic-mode-of-action of environmental contaminants. Nuclear Magnetic Resonance (NMR) spectroscopy has been commonly used in metabolomic studies; however, its main drawback is its ...
Monica Bastawrous   +14 more
doaj   +1 more source

Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

open access: yesNature Communications, 2020
Trapped ion mobility (TIMS)-mass spectrometry with parallel accumulation-serial fragmentation (PASEF) facilitates high-sensitivity proteomics experiments.
Catherine G. Vasilopoulou   +8 more
doaj   +1 more source

Nanoscale chemical and structural investigation of Mg-doped GaN nanowires using EDS and WDS on SEM [PDF]

open access: yesEPJ Web of Conferences
Semiconductors are the basis of many of today's technical products and therefore an important foundation of our modern economy. One material that is currently the subject of intensive research is doped gallium nitride (GaN), which has outstanding ...
Abratis Michael   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Viscosity of yttrium oxide (Y2O3) and magnesium-aluminum spinel (MgAl2O4) nanopowder suspensions in ethyl alcohol

open access: yesArchives of Mechanics, 2013
We report results of rheological experiments on suspensions of nanopowders. In this work we have used two ceramic nanopowders such as magnesium-aluminum spinel (S30CR Baikowski – MgAl2O4) and yttrium oxide (Y2O3) suspended in ethyl alcohol.
M. Cholewa   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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