Results 81 to 90 of about 610,910 (337)
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun+13 more
wiley +1 more source
EPR Study of Spin Labeled Brush Polymers in Organic Solvents [PDF]
Spin-labeled polylactide brush polymers were synthesized via ring-opening metathesis polymerization (ROMP), and nitroxide radicals were incorporated at three different locations of brush polymers: the end and the middle of the backbone, and the end of ...
Burts, Alan O.+7 more
core +2 more sources
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han+7 more
wiley +1 more source
Hydrogen embrittlement (HE) poses the risk of premature failure for many metals, especially high-strength steels. Due to the utilization of hydrogen as an environmentally friendly energy source, efforts are made to improve the resistance to HE at ...
Jens Jürgensen+4 more
doaj +1 more source
Surface modification using mussel‐derived polydopamine (PDA) is a versatile and robust biocompatible strategy that enables direct application to various epidermal surfaces, regardless of their morphological complexity or surface characteristics. The PDA‐coated epidermis exhibits multiple anti‐biofouling functionalities, including antibacterial and anti‐
Su Eon Lee+14 more
wiley +1 more source
The publication of Magritte’s complete writings in a volume edited by Andre Blavier means that the Belgian painter will be joining fellow artists Malevich and Matisse on the M-shelves of French booksellers. According to Schwitters, this is very much the elite bookshelf for 20th-century art, containing as it does the Monstructivists Malevich, Moholy ...
openaire +2 more sources
Molecular dynamics simulations of a short-chain polymer melt between two brush-covered surfaces under shear have been performed. The end-grafted polymers which constitute the brush have the same chemical properties as the free chains in the melt and ...
Allen M. P.+8 more
core +1 more source
Engineering of a functional protein corona with a synergistic heparin‐ATIII complex significantly improves hemocompatibility of PEG nanoparticles. Through deliberate engineering of the protein corona, a 4‐fold reduction in coagulation activation (F1 + 2) without inducing adverse thromboinflammatory reactions (CD11b, C5a) is achieved without disrupting ...
Vaidehi Londhe+5 more
wiley +1 more source
Improving California brush ranges / [PDF]
C37
Jones, Burle J. (Burle Jackson), 1880-1978+1 more
core +2 more sources
Geometrically Controlled WNT Activation Drives Intestinal Morphogenesis
Crypt‐villi‐like morphogenesis can be driven and controlled via architectural patterns in colorectal cells with the use of digital light processing printing. The resulting mini tissues exhibit budding structures and functionality, as evidenced by increased mucin expression.
Nathaniel C. Burmas+3 more
wiley +1 more source