Destruction of the brush border by Salmonella enterica sv. Typhimurium subverts resorption by polarized epithelial cells [PDF]
Salmonella enterica serovar Typhimurium is an invasive, facultative intracellular gastrointestinal pathogen that destroys the brush border of polarized epithelial cells (PEC).
Alfonso Felipe-López+3 more
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Molecular model of the microvillar cytoskeleton and organization of the brush border. [PDF]
Brush border microvilli are approximately 1-microm long finger-like projections emanating from the apical surfaces of certain, specialized absorptive epithelial cells.
Jeffrey W Brown, C James McKnight
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The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac [PDF]
Brush border gene regulation in various different tissues is incompletely understood. Here, the authors show HNF4 regulates the brush border gene program in multiple organs, such as intestine, kidney and yolk sac, and also intestinal chromatin looping in
Lei Chen+18 more
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Food-Grade Metal Oxide Nanoparticles Exposure Alters Intestinal Microbial Populations, Brush Border Membrane Functionality and Morphology, In Vivo (Gallus gallus) [PDF]
Among food additive metal oxide nanoparticles (NP), titanium dioxide (TiO₂) and silicon dioxide (SiO₂) are commonly used as food coloring or anti-caking agents, while zinc oxide (ZnO) and iron oxide (Fe₂O₃) are added as antimicrobials and coloring agents,
Jacquelyn Cheng+5 more
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The Influence of Peptidases in Intestinal Brush Border Membranes on the Absorption of Oligopeptides from Whey Protein Hydrolysate: An Ex Vivo Study Using an Ussing Chamber [PDF]
For many years, it was believed that only amino acids, dipeptides, and tripeptides could be absorbed and thus reach the bloodstream. Nowadays, the bioavailability of oligopeptides is also considered possible, leading to new research.
Luísa Ozorio+5 more
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Protein landscape of the brush border membrane of first instar larvae of Frankliniella occidentalis, the western flower thrips. [PDF]
We investigated the protein composition of the brush border membrane of larval Frankliniella occidentalis (western flower thrips), an agriculturally significant crop pest and vector of plant pathogens.
Marlonni Maurastoni+4 more
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Intestinal brush border assembly during the peri-hatch period and its contribution to surface area expansion [PDF]
Microvilli generate the small intestinal brush border, the main site of nutrient digestion and absorption. Mucosal structuring of the small intestine of chicken during the perihatch period has been widely researched, yet the developmental dynamics of ...
Naama Reicher, Zehava Uni
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A Fast and Accurate Method to Identify and Quantify Enzymes in Brush-Border Membranes: In Situ Hydrolysis Followed by Nano LC-MS/MS [PDF]
A simple method for the identification of brush-border membrane α-glucosidases is described. The proteins were first solubilized and separated in a gel under native, non-denaturing, conditions.
Antonio Brun+5 more
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The intermicrovillar adhesion complex in gut barrier function and inflammation
The surface of intestinal epithelial cells is covered by the brush border, which consists of densely packed cellular extrusions called microvilli. Until recently, microvilli have not been known to be interconnected. In 2014, a protein complex, called the
Bernadette Mödl+3 more
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Levels of disaccharidases in the brush border membrane of equine small intestine [PDF]
The disaccharides, consisting of sucrose, lactose and maltose, are hydrolysed into monosaccharides (D-glucose, D-galactose and D-fructose) by intestinal brush border enzymes: sucrase, lactase and maltase.
Miran A. Al-Rammahi
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