Results 31 to 40 of about 33,690 (269)

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

open access: yesAdvanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova   +4 more
wiley   +1 more source

Nexus of the Location of Performance of an Obligation as the Basis of Jurisdiction in the Brussels I bis Regulation in Cases Versus Air Carriers

open access: yesLeXonomica, 2021
As it is correctly emphasized by the European Union (EU) legislator, actions in the field of air transport should aim, among other things, at ensuring a high level of protection for passengers. The paper attempts to discuss the nexus of the location of performance of an obligation as the basis of special jurisdiction in the context of the Brussels I ...
Gołaczyński, Jacek, Zalisko, Marek
openaire   +2 more sources

Broadening the semiaquatic scene: Quantification of long bone microanatomy across pinnipeds

open access: yesThe Anatomical Record, EarlyView.
Abstract Investigations of bone microanatomy are commonly used to explore lifestyle strategies in vertebrates. While distinct microanatomical limb bone features have been established for exclusively aquatic and terrestrial lifestyles, identifying clear patterns for the semiaquatic lifestyle remains more challenging.
Apolline Alfsen   +10 more
wiley   +1 more source

Art. 67 Brussels I bis Regulation: An Overall Critical Analysis

open access: yes, 2021
Building upon the results of the En2Bria EU cofunded research project, the work addresses the relationship between the Brussels I bis Regulation and special rules on jurisdiction and recognition and enforcement of decisions contained in other EU law instruments.
Ilaria Queirolo   +5 more
openaire   +3 more sources

Culpa in Contrahendo: A Testimony to the Changing Methodologies in Private International Law

open access: yesReview of European and Comparative Law
The concept of culpa in contrahendo traditionally encompasses cases of disloyal conduct by the parties during the negotiation stage of a contract. It applies to a broad range of factual scenarios.
Maria-Anna Zachariasiewicz   +1 more
doaj   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet   +17 more
wiley   +1 more source

Determining competent jurisdiction in cross-border art disputes

open access: yesНауковий вісник Ужгородського національного університету. Серія Право
Throughout history, armed conflicts have often been accompanied by the unlawful export and looting of cultural property. The ongoing war in Ukraine is, regrettably, no exception.
B. Kryvolapov
doaj   +1 more source

Broadband : towards a national plan for Scotland [PDF]

open access: yes, 2012
The development of national broadband plans has been used by many countries to join up different areas of governmental and regulatory activities and to set ambitious targets for ubiquitous access to and use of the latest fixed and wireless networks and ...
Lockyer, Cliff, Sutherland, Ewan
core  

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang   +7 more
wiley   +1 more source

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