Results 211 to 220 of about 212,526 (280)
Modulating the Binding Kinetics of Bruton's Tyrosine Kinase Inhibitors through Transition-State Effects. [PDF]
J Am Chem SocBravo E, Li Y, Lin DY, Srinivasan B, Barone M, Li SX, DelloRusso F, Rahiyanath AS, Corrionero A, Alfonso P, Prendiville N, Kozakov D, Andreotti AH, Tonge PJ. +13 moreeuropepmc +1 more sourceDiscovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers
, 2016 Scott H. Watterson, George V. De Lucca, Qing Shi, Charles M. Langevine, Qingjie Liu, Douglas G. Batt, Myra Beaudoin Bertrand, Hua Gong, Jun Dai, Shiuhang Yip, Peng Li, Dawn Sun, Dauh–Rurng Wu, Chunlei Wang, Yingru Zhang, Sarah C. Traeger, Mark A. Pattoli, Stacey Skala, Lihong Cheng, Mary T. Obermeier, Rodney Vickery, Lorell Discenza, Celia D’Arienzo, Yifan Zhang, Elizabeth Heimrich, Kathleen M. Gillooly, Tracy Taylor, Claudine Pulicicchio, Kim W. McIntyre, Michael A. Galella, Andy J. Tebben, J.K. Muckelbauer, ChiehYing Chang, Richard Rampulla, Arvind Mathur, Luisa Salter–Cid, Joel C. Barrish, Percy H. Carter, Aberra Fura, James R. Burke, Joseph A. Tino +40 moreopenalex +1 more sourceThe splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia [PDF]
, 2015 Aymerich, Marta, Campo, Elías, Colomer, Dolors, Lagisetti, Chandraiah, López Guerra, Mónica, López Otín, Carlos, Montraveta, Arnau, Rodríguez, Vanina, Roldán, Jocabed, Rosich, Laia, Villamor Casas, Neus, Webb, Thomas R., Xargay-Torrent, Sçilvia +12 morecore +1 more sourceThe new Bruton's tyrosine kinase inhibitors SPA8007 and SPA8009 reduce stemness and invasiveness of patient-derived glioblastoma tumorspheres. [PDF]
Transl OncolJo E, Lee E, Oh Y, Lee D, Lee B, Kim K, Choi RJ, Hong J, Jeon Y, Cho H, Choi YS, Kim S, Won SY, Choi S, Roh TH, Moon JH, Kim EH, Chang JH, Jeon R, Kang SG. +19 moreeuropepmc +1 more sourceAminopyrazole Carboxamide Bruton’s Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning
, 2018 Mark E. Schnute, Stephen Benoit, Ingrid P. Buchler, Nicole Caspers, Margaret L. Grapperhaus, Seungil Han, Rajeev Hotchandani, Nelson Huang, Robert Hughes, Brian Juba, Kyung‐Hee Kim, Erica Liu, Erin L. McCarthy, Dean Messing, Joy Miyashiro, Shashi Mohan, Thomas N. O’Connell, Jeffrey F. Ohren, Mihir D. Parikh, Michelle Schmidt, Shaun R. Selness, John R. Springer, V. Thanabal, John I. Trujillo, Daniel P. Walker, Zhao‐Kui Wan, Jane M. Withka, Arthur J. Wittwer, Nancy L. Wood, Lei Xing, Christoph W. Zapf, John Douhan +31 moreopenalex +2 more sourcesAbility of Bruton’s Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling
Molecular Pharmacology, 2017 Andrew T. Bender, A. Gardberg, A. Pereira, Theresa L. Johnson, Yin Wu, R. Grenningloh, J. Head, F. Morandi, P. Haselmayer, L. Liu-Bujalski +9 moresemanticscholar +1 more source
