Results 201 to 210 of about 78,184 (307)
ABSTRACT Background Although primarily reported in solid organ transplant recipients and patients undergoing chimeric antigen receptor T‐cell immunotherapy (CAR‐T), non‐hepatic hyperammonemia (NHHA) is a rare but lethal complication in the broader context of post‐ chemo‐immunotherapy hematologic malignancies.
Yinshan Wu +3 more
wiley +1 more source
Bruton's tyrosine kinase inhibitors in diffuse large B-cell lymphoma therapy: critical considerations and future innovations. [PDF]
Lu C +6 more
europepmc +1 more source
ABSTRACT Introduction Overweight and obesity are increasing rapidly in most countries. Underweight body mass index (BMI), though much less common, is also associated with adverse health outcomes. There is poor understanding of the implications of BMI in lymphoma patients.
Serif Sungur +14 more
wiley +1 more source
Discovery of Covalent Ligands with AlphaFold3. [PDF]
Shamir Y +5 more
europepmc +1 more source
ABSTRACT Introduction Marginal zone lymphoma (MZL) is an indolent yet incurable B‐cell malignancy in which targeted agents such as BTK and PI3K inhibitors frequently fail due to resistance or toxicity. Antimicrobial peptides (AMPs), evolutionarily conserved effectors of innate immunity, possess selective cytotoxicity against malignant cells by ...
Filippo Spriano +6 more
wiley +1 more source
UVI5008: the first reversible, non-covalent Bruton's tyrosine kinase epi-inhibitor for B-cell malignancies. [PDF]
Dell'Aversana C +19 more
europepmc +1 more source
ABSTRACT Objectives Targeted therapies have markedly improved outcomes in chronic lymphocytic leukaemia (CLL), particularly among patients with TP53 alterations and unmutated IGHV. However, real‐world studies report persistent inequalities in access to optimal care.
Susana Esteves +7 more
wiley +1 more source
When Targeted Therapy Falls Short: Unraveling Resistance Mechanisms in Chronic Lymphocytic Leukemia. [PDF]
Benrashid S, Woyach JA.
europepmc +1 more source
Mechanisms of resistance to bruton's tyrosine kinase inhibitors: synergistic effects of tumor microenvironment regulation and signaling pathways. [PDF]
Dong X +10 more
europepmc +1 more source

