Results 131 to 140 of about 21,331 (238)
Targeting lipid metabolism overcomes BTK inhibitor resistance in diffuse large B-cell lymphoma
Medicine in Novel Technology and DevicesExploring novel therapeutic targets of Diffuse large B cell lymphoma (DLBCL) to overcome its resistance to Bruton's Tyrosine Kinase (BTK) inhibitors is a key topic.
Zhuojun Liu +5 more
doaj +1 more source
The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design
ChemMedChem, Volume 21, Issue 7, 14 April 2026.Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia +4 more
wiley +1 more source
The Potential Therapeutic Role of Bruton Tyrosine Kinase Inhibition in Neurodegenerative Diseases
Applied SciencesBruton Tyrosine Kinase (BTK) has emerged as a critical mediator in the pathophysiology of neuroinflammation associated with neurodegenerative diseases.
Francesco D’Egidio +5 more
doaj +1 more source
From phagocytosis to metaforosis: calcineurin's deadly role in innate processing of fungi [PDF]
, 2018 Armstrong-James, D +3 more
core +3 more sources
Cell line‐based assessment of BTK inhibitors [PDF]
British Journal of Pharmacology, 2020 Günter Krause +2 more
openaire +2 more sources
Case Reports in HematologyIntroduction. The introduction of Bruton’s tyrosine kinase (BTK) inhibitors significantly improved the management of chronic lymphocytic leukemia (CLL). However, BTK carry the risk of cardiotoxicity, which is not only limited to atrial fibrillation. Case
Thomas Erblich +2 more
doaj +1 more source