[Efficacy and safety analysis of BTK inhibitors combined with R-CHOP regimen in newly diagnosed double-expressor diffuse large B-cell lymphoma]. [PDF]
Lu JB +9 more
europepmc +1 more source
Case report: BTK inhibitors is effective in type II mixed cryoglobulinemia with wild-type MyD88. [PDF]
Xu M +12 more
europepmc +1 more source
Identification of Potential Nontoxic Human <i>BTK</i> Inhibitors through an Integrated Deep Learning and Structure-Based Drug Repositioning Strategy. [PDF]
Iqbal MW, Sun X, Yuan Q.
europepmc +1 more source
Treatment of relapsed/refractory chronic lymphocytic leukemia with Zanubrutinib after progressing on other BTK inhibitors. [PDF]
Nwankwo N, Reddy A, Kumar S, Zafar M.
europepmc +1 more source
Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL. [PDF]
Gentile G +26 more
europepmc +1 more source
How I use genomics and BTK inhibitors in the treatment of Waldenström macroglobulinemia.
Treon SP, Sarosiek S, Castillo JJ.
europepmc +1 more source
Btk Inhibitors: A Medicinal Chemistry and Drug Delivery Perspective
In the past few years, Bruton's tyrosine Kinase (Btk) has emerged as new target in medicinal chemistry. Since approval of ibrutinib in 2013 for treatment of different hematological cancers (as leukemias and lymphomas), two other irreversible Btk ...
Chiara Brullo +2 more
exaly +3 more sources
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On-Target BTK Mutations Promote Resistance to Noncovalent BTK Inhibitors
Cancer Discovery, 2022Abstract Resistance to noncovalent BTK inhibitors is mediated by non-C481 BTK and PLCγ2 mutations.
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The role of noncovalent BTK inhibitors in the era of covalent BTK inhibitors.
Clinical advances in hematology & oncology : H&ODespite significantly improving outcomes in patients with B-cell malignancies, covalent Bruton tyrosine kinase (BTK) inhibitors are limited by toxicities and the development of resistance. Some toxicities can be life-threatening, such as cardiotoxicity.
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