Results 61 to 70 of about 4,101 (234)

Efficacy and Safety Profile of a Rituximab, Methotrexate, and Thiotepa‐Based Regimen in Newly Diagnosed Primary CNS Lymphoma

open access: yesInternational Journal of Cancer, EarlyView.
Primary central nervous system diffuse large B‐cell lymphoma (PCNS‐DLBCL) lacks an optimal first‐line induction strategy, particularly for older patients and those ineligible for intensive consolidation. In this retrospective cohort of 36 newly diagnosed patients, the rituximab + methotrexate + thiotepa (RMT) regimen as first‐line induction achieved ...
Haotian Wang   +10 more
wiley   +1 more source

Cardiac Monitoring of Patients on Btki for Chronic Lymphocytic Leukemia [PDF]

open access: bronzeBlood
Background: The first-in-class Bruton tyrosine kinase inhibitor (BTKi) ibrutinib is associated with an increased risk of atrial fibrillation (AF), ventricular arrhythmia, and sudden death. While next-generation BTKis, acalabrutinib and zanubrutinib, are more selective, growing evidence has ...
Christine Gruessner   +12 more
openalex   +2 more sources

ANALISIS INTERAKSI GENOTIPE LINGKUNGAN MENGGUNAKAN PARTIAL LEAST SQUARE PATH MODELING [PDF]

open access: yes, 2009
Percobaan multilokasi telah banyak digunakan oleh para pemulia tanaman untuk mengkaji kemampuan realatif genotipe-genotipe pada berbagai Lokasi tanam dengan tujuan menemukan genotipe-genotipe unggulan.
I Gede Nyoman Mindra, Jaya
core  

PENGARUH LIKUIDITAS, RISIKO KREDIT DAN CAPITAL ADEQUACY RATIO TERHADAP PROFITABILITAS PERBANKAN DI BURSA EFEK INDONESIA (Studi Pada Perusahaan Perbankan Di Indonesia Periode 2015-2018) [PDF]

open access: yes, 2020
Penelitian ini bertujuan untuk menguji dan menganalisis pengaruh Likuiditas terhadap Profitabilitas, Risiko Kredit terhadap Profitabilitas, Capital Adequacy Ratio terhadap Profitabilitas dan Likuiditas, Risiko Kredit, Capital Adequacy terhadap ...
MACHFUD, ROBBY ARIA
core  

Patient‐reported health‐related quality of life in previously untreated chronic lymphocytic leukaemia: Results from the randomised phase 3 FLAIR trial comparing ibrutinib–rituximab versus fludarabine–cyclophosphamide–rituximab

open access: yesBritish Journal of Haematology, EarlyView.
Summary Front‐Line therapy in CLL: Assessment of Ibrutinib‐containing Regimens (FLAIR) demonstrated improved progression‐free survival for ibrutinib and rituximab (IR) compared with fludarabine, cyclophosphamide and rituximab (FCR) in previously untreated chronic lymphocytic leukaemia (CLL).
David J. Allsup   +23 more
wiley   +1 more source

Renal dysfunction in symptomatic Waldenström macroglobulinaemia: A nationwide Italian multicentre study

open access: yesBritish Journal of Haematology, EarlyView.
Renal dysfunction represents a possible underrecognized complication of symptomatic WM; this condition correlates with adverse global and disease‐specific clinical outcomes. Summary The prognostic significance of impaired renal function in Waldenström macroglobulinaemia (WM) remains poorly defined.
Nicolò Danesin   +27 more
wiley   +1 more source

The impact of Bruton’s tyrosine kinase inhibitor treatment on COVID-19 outcomes in Chinese patients with chronic lymphocytic leukemia

open access: yesFrontiers in Oncology
BackgroundImpact of B-cell depletion following treatment with Bruton tyrosine kinase-inhibitors (BTKi) on the outcome of SARS-CoV-2 infection in chronic lymphocytic leukemia (CLL) patients remain controversial.
Shenmiao Yang   +8 more
doaj   +1 more source

Transition Into Clinical Routine and Survival Outcomes of BCL2‐ and BTK Inhibitors: An Analysis of Patient Data From the GCLLSG Registry

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Within a dataset of the German CLL Study Group (GCLLSG) registry, 274 patients were allocated to a cohort with venetoclax and 888 to a cohort with BTKi (79 acalabrutinib, 809 ibrutinib), each as first administered targeted substance class within the documented treatment sequence.
Nadine Kutsch   +16 more
wiley   +1 more source

First‐Line Treatment of IGHV‐Unmutated Chronic Lymphocytic Leukemia: A Network Meta‐Analysis of Targeted and Chemoimmunotherapy Regimens

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Immunoglobulin heavy chain variable region‐unmutated (IGHV‐U) chronic lymphocytic leukemia (CLL) represents a biologically aggressive subgroup with limited responsiveness to chemoimmunotherapy (CIT). To clarify the comparative effectiveness of available frontline options, we conducted a comprehensive Bayesian network meta‐analysis of ...
Santino Caserta   +13 more
wiley   +1 more source

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