Results 41 to 50 of about 122,190 (266)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Experimental study on solution and diffusion process of single carbon dioxide bubble in seawater

open access: yesMechanical Engineering Journal, 2016
Solution and diffusion process of carbon dioxide (CO2) in seawater is important in the research and development of CO2 ocean sequestration technology to mitigate global warming.
Qiusheng LIU   +4 more
doaj   +1 more source

Investigation of Recirculating Marangoni Flow in Three-Dimensional Geometry of Aqueous Micro-Foams

open access: yesFluids, 2023
Experimental investigations of Marangoni flow in micro-foams have faced challenges due to the inherent difficulties in detecting and measuring this flow.
Nastaran Rezaee, John Aunna, Jamal Naser
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Blowing bubbles: Dermoscopy of bubble hair

open access: yesInternational Journal of Trichology, 2017
Exposing wet hair to high temperatures can create gas bubbles within the hair shaft, leading to brittle, dry hairs in a disorder known as bubble hair abnormality. We present a case of a 61-year-old woman who presented for hair breakage over her crown. She regularly dried her damp hair with a blow dryer.
Albers, Lauren N   +2 more
openaire   +3 more sources

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Bubbles Tomorrow and Bubbles Yesterday, but Never Bubbles Today? [PDF]

open access: yesBusiness Economics, 2013
Considering their importance and the amount of effort that has gone into understanding them, asset price bubbles continue to perplex. The evidence of these bubbles seldom squares with what would be expected from standard asset price theory. Unlike the suggestions from theory, expectations of prices of both stocks and houses tend to be procyclical—price
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Theoretical Modeling of Bubbling Regimes in Bubble Formation with Bubble-Bubble and Bubble-Wall Interactions

open access: yesJOURNAL OF CHEMICAL ENGINEERING OF JAPAN, 2008
In this study, a theoretical model for prediction of bubbling regimes in bubble formation from a single submerged orifice has been developed. The model takes into account both chamber pressure fluctuations, and bubble–bubble and bubble–wall interactions on bubbling regimes.
Xiao, Z. Y., Tan, R. B. H.
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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