Results 101 to 110 of about 49,757 (329)

Pharmacogenomic testing and its future in community pharmacy [PDF]

, 2020
Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core   +1 more source

Dental fluorosis in the European roe deer (Capreolus capreolus): A review of the pathological changes in the enamel of fluorotic cheek teeth and the abnormal pattern of dental wear in affected dentitions

The Anatomical Record, EarlyView.
Abstract This article reviews the pathological changes in the enamel of permanent mandibular cheek teeth and their sequelae in European roe deer from regions polluted by anthropogenic fluoride emissions. The primary (developmental) changes of fluorotic roe deer enamel are hypomineralization and microstructural aberrations, including enamel hypoplasia ...
Uwe Kierdorf, Horst Kierdorf
wiley   +1 more source

Design, development, and optimization of mucoadhesive buccal films of ganaxolone for enhanced bioavailability

Journal of Applied Pharmaceutical Research
Background: CDD disorder affects children mainly during their first three months of life. The buccal route offers advantages over oral administration for ganaxolone by avoiding first-pass metabolism and providing direct systemic absorption.
Onkar Pawar, Rahul Godge, Ganesh Shinde, Kailas Barde, Akshay Vikhe   +4 more
doaj   +1 more source

Silesaurid (Archosauria: Dinosauriformes) remains from the base of the Dockum Group (Late Triassic: Otischalkian) of Texas provide new insights to the North American record of dinosauriforms

The Anatomical Record, EarlyView.
Abstract Silesaurids (Archosauria: Dinosauriformes) are found in Middle to Upper Triassic deposits across Pangea, but few stratigraphic sections record the evolution of the group in one geographic area over millions of years. Here, we describe silesaurid remains from the oldest of the Upper Triassic stratigraphic sequence from the base of the Dockum ...
Frederick B. Tolchard, Brynden W. Perkins, Sterling J. Nesbitt   +2 more
wiley   +1 more source

N-alkylamides : from plant to brain [PDF]

, 2014
Background: Plant N-alkylamides (NAAs) are bio-active compounds with a broad functional spectrum. In order to reach their pharmacodynamic targets, they have to overcome several barriers of the body in the absorption phase.
De Spiegeleer, Bart, Joshi, Tanmayee, Taevernier, Lien, Tatke, Pratima, Verbeke, Frederick, Veryser, Lieselotte, Wynendaele, Evelien   +6 more
core  

Current and evolving approaches for improving the oral permeability of BCS Class III or analogous molecules [PDF]

, 2016
The Biopharmaceutics Classification System (BCS) classifies pharmaceutical compounds based on their aqueous solubility and intestinal permeability. The BCS Class III compounds are hydrophilic molecules (high aqueous solubility) with low permeability ...
Dave, Vivek S, Gupta, Deepak, Gupta, Sheeba Varghese, Nguyen, Phong, Yu, Monica   +4 more
core   +2 more sources

Shaping the human face: Periosteal bone modeling across ontogeny

The Anatomical Record, EarlyView.
Abstract Facial morphology is a defining aspect of Homo sapiens that distinguishes our species from fossil ancestors and plays a central role in estimating age, sex, and ancestry in both past and present populations. Understanding how the face develops during postnatal ontogeny is essential for interpreting adult facial variation.
Sarah E. Freidline, Madison Hubbart, Catherine Shipman, Najielie Burgos, Chiara Villa, Alexandra Schuh   +5 more
wiley   +1 more source

The lower jaw of Devonian ray‐finned fishes (Actinopterygii): Anatomy, relationships, and functional morphology

The Anatomical Record, EarlyView.
Abstract Actinopterygii is a major extant vertebrate group, but limited data are available for its earliest members. Here we investigate the morphology of Devonian actinopterygians, focusing on the lower jaw. We use X‐ray computed tomography (XCT) to provide comprehensive descriptions of the mandibles of 19 species, which span the whole of the Devonian
Ben Igielman, Rodrigo Tinoco Figueroa, Robert R. Higgins, Stephanie E. Pierce, Michael I. Coates, Emily M. Troyer, Vincent Fernandez, Kathleen Dollman, Jing Lu, Min Zhu, Matt Friedman, Sam Giles   +11 more
wiley   +1 more source

Integrating mandibular evidence to assess morphological variation of the Australopithecus afarensis maxilla

The Anatomical Record, EarlyView.
Abstract Geometric morphometric analyses are used to explore variation of maxillary dental arcades of Australopithecus afarensis, expanding on the work of Hanegraef and Spoor, 2025 (Morphological variation of the Australopithecus afarensis maxilla.
Hester Hanegraef, Romain David, Fred Spoor   +2 more
wiley   +1 more source

Oral Manifestations in Acute Leukemia as the First Sign; The Interdisciplinary Approach of Diagnosis and Treatment [PDF]

, 2015
Systemic diseases often present associated oral signs and symptoms, which can occur either from the beginning of the disease or during its evolution. In some cases the oral manifestations reveal an undetected and severe disease, like leukemia.
Anca, Dumitriu, Marina, Giurgiu, Stana, Paunica   +2 more
core   +2 more sources