Results 141 to 150 of about 49,757 (329)

Efficacy of Eribulin Monotherapy in Patients With Unresectable and/or Metastatic Adenoid Cystic Carcinoma Receiving Platinum‐Based Therapy

Head &Neck, EarlyView.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is the second most common and treatment‐resistant salivary gland carcinoma (SGC). Although platinum‐based therapies are effective, the efficacy of eribulin, a microtubule inhibitor with an 18% response rate in a Phase II trial involving recurrent/metastatic SGC, in patients with advanced ACC after ...
Tomomi Sanomachi, Tatsunori Shimoi, Yuki Kojima, Hideaki Takahashi, Motoko Arakaki, Asuka Kawachi, Hitomi Sumiyoshi Okuma, Mai Hoshino, Munehiro Ito, Ayumi Saito, Shosuke Kita, Aiko Maejima, Tadaaki Nishikawa, Kazuki Sudo, Taisuke Mori, Yasuhiro Fujiwara, Kan Yonemori   +16 more
wiley   +1 more source

Transport of Non-Steroidal Anti-Inflammatory Drugs across an Oral Mucosa Epithelium In Vitro Model

Pharmaceutics
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most prescribed drugs to treat pain or fever. However, oral administration of NSAIDs is frequently associated with adverse effects due to their inhibitory effect on the constitutively ...
Grace C. Lin, Heinz-Peter Friedl, Sarah Grabner, Anna Gerhartl, Winfried Neuhaus   +4 more
doaj   +1 more source

Absorption of Vitamin B12 in Pernicious Anaemia: IV. Administration into Buccal Cavity, into Washed Segment of Intestine, or after Partial Sterilization of Bowel [PDF]

, 1950
C. C. Ungley
openalex   +1 more source

Conversion Surgery After Administration of a TRK Inhibitor for Unresectable Parotid Gland Secretory Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background The NTRK fusion gene is detected in most salivary gland secretory carcinomas. While tropomyosin receptor kinase (TRK) inhibitors are used for various solid tumors with the fusion gene, there are no reports regarding TRK inhibitor use for unresectable parotid gland carcinomas that subsequently shrink and become resectable.
Arisa Nagano, Takuma Matoba, Daisuke Kawakita, Kiyoshi Minohara, Sho Iwaki, Hiroshi Tsuge, Koji Tsukamoto, Sekai Kikuchi, Satsuki Nakano, Takayuki Murase, Yuichiro Tada, Shinichi Iwasaki   +11 more
wiley   +1 more source

Rapid repeated buccal administration of nitroglycerin ointment is highly effective in preventing intubation in patients with acute cardiogenic pulmonary edema without cardiogenic shock [PDF]

, 2023
Mohammad Reza Movahed
openalex   +1 more source

The impact and management of hyperemesis gravidarum: Current and future perspectives

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy affecting around 1%–3% of pregnancies worldwide and is the most common reason for hospital admission in early pregnancy. HG can have lasting consequences for both pregnant individuals and their offspring.
L. M. van der Minnen, I. J. Grooten, C. Dean, J. Trovik, R. C. Painter   +4 more
wiley   +1 more source

Intranasal scopolamine preparation and method [PDF]

A new method and preparation for intranasal delivery of scopolamine provides a safe and effective treatment for motion sickness and other conditions requiring anticholinergic therapy. The preparation can be in the form of aqueous nasal drops, mist spray,
Cintron, Nitza M., Putcha, Lakshmi
core   +1 more source

Intraoperative administration of systemic/epidural/intrathecal morphine on the quality of recovery following substitutional urethroplasty with buccal mucosal graft: A randomized control trial

, 2022
Ramamani Mariappan, JuliyaPearl Joseph Johnson, Rajasekar Arumugam, Reka Karuppusami   +3 more
openalex   +1 more source

Physiologically Based Pharmacokinetic Modeling to Predict Nicotine Pharmacokinetics of Nicotine Pouches Under Naturalistic Use Conditions

The Journal of Clinical Pharmacology, EarlyView.
Abstract Adult users of traditional tobacco products like combustible cigarettes (CC) or moist smokeless tobacco (MST) products can reduce exposure to toxicants by switching to potentially less harmful alternatives such as tobacco‐free nicotine pouches (NP). Nicotine exposure assessment is an important consideration to determine the switching potential
Ali Salehi, Mohamadi A. Sarkar, Jennifer H. Smith, Ali A. Rostami   +3 more
wiley   +1 more source

Clinical Evaluation of Buccal Infiltration with Articaine for Endodontic Anesthesia in Mandibular Molars with Irreversible Pulpitis

Oral
Background and Objectives: This study investigates the efficacy of 4% articaine buccal infiltration in patients with mandibular molar irreversible pulpitis.
Maria Rachel Monteiro, Carlos Fernando Mourão, Maria Cristina Volpato, Francisco Carlos Groppo, Francisco Haiter-Neto, Roberto Sacco, José Flávio Affonso de Almeida   +6 more
doaj   +1 more source