Results 141 to 150 of about 2,139,463 (337)

Self-Reported Effectiveness and Safety of Trokie® Lozenges: A Standardized Formulation for the Buccal Delivery of Cannabis Extracts

Frontiers in Neuroscience, 2018
Therapeutic use of cannabinoids, the main active ingredients of Cannabissativa L., is often hindered by their limited bioavailability and undesirable psychoactivity. We conducted an observational study in December 2016 and another one in February 2018 to
Kenton Crowley, Sieta T. de Vries, Guillermo Moreno-Sanz, Guillermo Moreno-Sanz   +3 more
doaj   +1 more source

Rescue epilepsy medication and training: A comparison between midazolam use, guidelines, clinical practice, and possibilities in the UK and Norway

Epilepsia Open, EarlyView.
Abstract Objectives Status epilepticus (SE) is a prolonged epileptic seizure carrying significant risk of long‐term disability and death. Rescue therapies are prescribed for prehospital administration to terminate SE. This study compared prescribing practices of rescue therapies of midazolam in the UK and Norway.
Audrey McBride, Oliver Johannes Henning, Cecilie Johannessen Landmark, Lance Watkins, Samuel Tromans, Paul Basset, Paraskevi Triantafyllopoulou, Rohit Shankar   +7 more
wiley   +1 more source

Experimental Design Approach for the Formulation of Controlled Release Buccal Bilayer Tablets of Carvedilol

Journal of Integrated Health Sciences, 2018
Introduction: The absolute bioavailability of carvedilol is ~25% - 35% even though it rapidly and extensively absorbed following oral administration due to a significant degree of presystemic metabolism.
Vinodkumar D. Ramani, Girish U. Sailor, Maulik M. Patel, Ghanshyam R. Parmar, Avinash K. Seth   +4 more
doaj   +1 more source

85: Buccal versus vaginal misoprostol administration for cervical ripening [PDF]

, 2007
Zoi Russell, Timothy J. O’Leary, Kimberly Destefano, Aaron J. Deutsch, S. J. Carlan   +4 more
openalex   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

Exploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li, Haonan Xing, Abid Naeem, Kaiyue Zhang, Aiping Zheng, Yuanyu Huang, Mei Lu   +6 more
wiley   +1 more source

Postoperative Pain After The Use Of A Dexamethasone Rinse As An Irrigant Prior To Obturation [PDF]

, 2013
Purpose: The purpose of this randomized, double-blind pilot study was to determine the effect of dexamethasone on post-operative pain when used as an intracanal rinse prior to obturation.
Tarabishy, Kenan
core   +1 more source

Survival Impact and Risk Factors of Cervical Lymph Node Metastasis in Maxillary Gingival Squamous Cell Carcinoma: A Retrospective Study of 81 Patients

Head &Neck, EarlyView.
ABSTRACT Background This study aimed to investigate the survival impact and predictive factors of cervical lymph node metastasis (CLNM) in patients with maxillary gingival squamous cell carcinoma (MGSCC). Methods This retrospective study included 81 patients with MGSCC who underwent radical surgery from 2008 to 2018.
Takeshi Kuroshima, Naoya Kinoshita, Naoto Nishii, Yu Oikawa, Takuma Kugimoto, Hideaki Hirai, Hirofumi Tomioka, Yasuyuki Michi, Hiroyuki Harada   +8 more
wiley   +1 more source

Effect of a Home‐Based Exercise Program on Muscle Mass, Fatigue, and Health‐Related Quality of Life Among Patients with Oral Cancer: A Randomized Trial

Head &Neck, EarlyView.
ABSTRACT Background Patients with head and neck cancer (HNC) often experience deteriorated health‐related quality of life (HRQoL) and loss of body weight and muscle mass. The primary aim was to determine if a home‐based exercise program, aiming to increase physical activity (PA), could reduce muscle mass loss and fatigue.
Camilla Wallmander, Ingvar Bosaeus, Ewa Silander, Hedda Haugen Cange, Jan Nyman, Monika Fagevik Olsén, Elisabet Blomsterwall, Malin Berg, Eva Hammerlid   +8 more
wiley   +1 more source

Oncologic Safety of Facial‐Vessel–Based Buccinator Myomucosal Flaps for Tongue and Oral Floor Reconstruction: A Retrospective Multicenter Case–Control Study

Head &Neck, EarlyView.
ABSTRACT Background Buccinator myomucosal flaps (BMFs) have been proposed as a reconstructive solution for defects of the tongue and oral floor; however, their harvest requires preservation of the facial artery and vein. This study aimed to evaluate the oncologic safety of this approach compared with free fasciocutaneous flaps (FFF).
Luigi Angelo Vaira, Olindo Massarelli, Jerry Polesel, Andrea Ferri, Carlos M. Chiesa‐Estomba, Ignacio Navarro Cuéllar, Giuseppe Consorti, Giulio Cirignaco, Marco Cucurullo, Giovanni Salzano, Sourabh Padmanabhan, Abhijith George, Marzia Petrocelli, Javeria Ali, Jose A. González‐Garcia, Alfonso Manfuso, Tareck Ayad, Carlos Navarro Cuéllar, Fabiola Giudici, Jerome R. Lechien, Shawn T. Joseph, Chiara Copelli, Federico Biglioli, Silvano Ferrari, Giacomo De Riu   +24 more
wiley   +1 more source

Transport of Non-Steroidal Anti-Inflammatory Drugs across an Oral Mucosa Epithelium In Vitro Model

Pharmaceutics
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most prescribed drugs to treat pain or fever. However, oral administration of NSAIDs is frequently associated with adverse effects due to their inhibitory effect on the constitutively ...
Grace C. Lin, Heinz-Peter Friedl, Sarah Grabner, Anna Gerhartl, Winfried Neuhaus   +4 more
doaj   +1 more source