Results 51 to 60 of about 49,757 (329)

The effect of transmucosal 0.2mg/kg Midazolam premedication on dental anxiety, anaesthetic induction and psychological morbidity in children undergoing general anaesthesia for tooth extraction [PDF]

, 2008
<b>Background:</b> The project aims were to evaluate the benefit of transmucosal Midazolam 0.2mg/kg pre-medication on anxiety, induction behaviour and psychological morbidity in children undergoing general anaesthesia (GA) extractions. <b&
A Keaney, A. J. Asbury, A. W. Bowman, AL Erlandsson, C Campbell, C Hogg, CK Schmidt, CM Bridgman, D Turkington, GM Humphris, H Buchanan, HM Parsons, HM Wong, J Elander, J Elander, J Rayner, JW Cole, K Millar, K Millar, K. Martin, K. Millar, LM Macpherson, M Rutter, M. T. Hosey, MA Lumley, MI Houpt, MT Hosey, MT Hosey, MT Hosey, NM Girdler, PA Lonnqvist, R Holn-Knudsen, R Seed, R. Welbury, S Calipel, T Horiuchi, T. Musiello, TA Bates, TK Howell, TN Johnson, V Carstairs, YP Ko   +41 more
core   +1 more source

Microemulsion containing triamcinolone acetonide for buccal administration

European Journal of Pharmaceutical Sciences, 2018
The aim of the present work was to investigate the potential of microemulsions for the buccal administration of triamcinolone acetonide. Microemulsions were developed by the construction of pseudoternary phase diagrams, using the aqueous titration method.
C. Padula, I. Telò, A. Di Ianni, S. Pescina, S. Nicoli, P. Santi   +5 more
openaire   +4 more sources

Facilitated Buccal Insulin Delivery via Hydrophobic Ion-Pairing Approach: In vitro and ex vivo Evaluation

International Journal of Nanomedicine, 2021
Santosh Bashyal,1 Jo-Eun Seo,1 Taekwang Keum,1,2 Gyubin Noh,1,2 Shrawani Lamichhane,1,2 Jeong Hwan Kim,1,2 Chang Hyun Kim,3 Young Wook Choi,3 Sangkil Lee1,2 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2Center for Forensic ...
Bashyal S, Seo JE, Keum T, Noh G, Lamichhane S, Kim JH, Kim CH, Choi YW, Lee S   +8 more
doaj  

To Compare the Efficacy of Preoperative Oral Medication of Ibuprofen and Ketorolac on Anesthetic Efficacy of Maxillary Buccal Infiltration Using Buffered 2% Lidocaine with 1:100,000 Adrenaline with Irreversible Symptomatic Pulpitis: A Prospective Clinical Study [PDF]

Dental Journal of Advance Studies
Aim: To assess the effects of ibuprofen and ketorolac, two preoperative oral medications on the effectiveness of anesthesia for maxillary buccal infiltration with buffered 2% lidocaine and 1:100,000 adrenaline in patients with irreversible symptomatic ...
Neha Menrai, Sameer Makkar, Sandeep Gupta, Ajay Aryan, Chetna Tarnach   +4 more
doaj   +1 more source

Silodosin oral films: Development, physico-mechanical properties and in vitro dissolution studies in simulated saliva [PDF]

, 2019
Sublingual film dosage forms for drugs used for fast symptomatic treatment have promise because they allow a rapid onset of action. The aim of this study was to prepare films of silodosin intended for sublingual administration for the symptomatic ...
Adair, Alhayali, Allam, Alonzo, Boateng, Brady, Brouwers, Campisi, Chapple, Curatolo, De Caro, El-Setouhy, ElMeshad, Gao, Garsuch, Gittings, Guo, Hanif, Hobbs, Huang, Humphrey, Jug, Kalia, Kapoor, Kim, Koland, Korhonen, Li, Liew, Madhav, Mashru, Matsubara, Miller-Chou, Montorsi, Nagy, Patel, Prabhu, Prasad, Preis, Preis, Preis, Radebaugh, Repka, Rossi, Runja, Sharma, Singh, Singh, Singh, Singh, Slavkova, Tanno, Vila, Visser, Vuddanda, Vuddanda, Yang, Zhang   +57 more
core   +2 more sources

Development of Tizanidine HCl-Meloxicam loaded mucoadhesive buccal films: In-vitro and in-vivo evaluation. [PDF]

PLoS ONE, 2018
The purpose of the study was to develop Tizanidine HCl (TZN) and Meloxicam (MLX) loaded bilayer mucoadhesive films intended for buccal administration, aiming to enhance the bioavailability.
Muhammad Zaman, Muhammad Hanif, Zaib Ali Shaheryar   +2 more
doaj   +1 more source

Concept for a Unidirectional Release Mucoadhesive Buccal Tablet for Oral Delivery of Antidiabetic Peptide Drugs Such as Insulin, Glucagon-like Peptide 1 (GLP-1), and their Analogs

Pharmaceutics, 2023
Injectable peptides such as insulin, glucagon-like peptide 1 (GLP-1), and their agonists are being increasingly used for the treatment of diabetes. Currently, the most common route of administration is injection, which is linked to patient discomfort as ...
Anubhav Pratap-Singh, Yigong Guo, Alberto Baldelli, Anika Singh   +3 more
doaj   +1 more source

Comparative Evaluation of Alveolar Nerve Block with 2% Lidocaine–Epinephrine and 4% Articaine–Epinephrine Buccal Infiltration in Mandibular Premolar and Molar Region in Children: A Double-Blind, Randomized Trial

Children
Background/Objectives: Effective pain control in pediatric dentistry combines behavior management, local anesthesia, and follow-up care. This study compared the efficacy of inferior alveolar nerve block (IANB) with 2% lidocaine and epinephrine versus ...
Jelena Komsic, Sanja Vujkov, Isidora Neskovic, Duska Blagojevic, Ana Tadic, Bojan Petrovic, Branislav Bajkin   +6 more
doaj   +1 more source

DNA methylation at the DAT promoter and risk for psychopathology. Intergenerational transmission between school-age youths and their parents in a community sample [PDF]

, 2018
Background: The effect of gene polymorphisms and promoter methylation, associated with maladaptive developmental outcomes, vary depending on environmental factors (e.g., parental psychopathology).
Claudio D’Addario, Claudio D’Addario, Eleonora Marzilli, Esterina Pascale, Giulia Ballarotto, Luca Cerniglia, Renata Tambelli, Silvia Cimino, Walter Adriani, Walter Adriani   +9 more
core   +2 more sources

Drug Bioavailability Enhancing Agents of Natural Origin (Bioenhancers) that Modulate Drug Membrane Permeation and Pre-Systemic Metabolism

Pharmaceutics, 2019
Many new chemical entities are discovered with high therapeutic potential, however, many of these compounds exhibit unfavorable pharmacokinetic properties due to poor solubility and/or poor membrane permeation characteristics. The latter is mainly due to
Bianca Peterson, Morné Weyers, Jan H. Steenekamp, Johan D. Steyn, Chrisna Gouws, Josias H. Hamman   +5 more
doaj   +1 more source