Results 51 to 60 of about 27,341 (167)

5-methyl-pyrrolidinone chitosan films as carriers for buccal administration of proteins [PDF]

AAPS PharmSciTech, 2006
The purpose of this research was to investigate 5-methyl-pyrrolidinone chitosan (MPC) films as carriers for buccal delivery of protein drugs. Placebo and protein-loaded MPC films were prepared by casting and were then cross-linked with tripolyphosphate at different pH conditions.
C. Colonna, Ida Genta, Paola Perugini, Franca Pavanetto, Tiziana Modena, Maurizia Valli, Corrado Muzzarelli, Bice Conti   +7 more
openalex   +5 more sources

Buccal, intranasal or intravenous lorazepam for the treatment of acute convulsions in children in Malawi: An open randomized trial

African Journal of Emergency Medicine, 2015
Acute convulsions in children are a common emergency worldwide. Benzodiazepines are the recommended first line treatment. Intravenous lorazepam is inexpensive, long acting and the first line drug in resource-rich settings. However, comparable efficacy by
Samantha Lissauer, Julia Kenny, Oliver Jefferis, Tom Wingfield, Anne Miller, George Chagaluka, Linda Kalilani-Phiri, Elizabeth Molyneux   +7 more
doaj   +1 more source

How Successful is Supplemental Intraseptal and Buccal Infiltration Anaesthesia in the Mandibular Molars of Patients Undergoing Root Canal Treatment or Tooth Extraction?

eJournal of Oral Maxillofacial Research, 2020
Objectives: To investigate the success rate of supplemental intraseptal and buccal infiltration anaesthesia in mandibular molars undergoing endodontic therapy/extraction when the inferior alveolar nerve block has failed.
Giath Gazal, Rayan Bahabri, Albraa B. Alolayan, Mahmod Alkayyal, Rahaf Al-Ghamdi, Ruwaa Salamah   +5 more
doaj   +1 more source

Syringic acid may attenuate the oral mucosal carcinogenesis via improving cell surface glycoconjugation and modifying cytokeratin expression

Toxicology Reports, 2018
Syringic acid (SRA) is an excellent anti-oxidant and anti-cancer property in various in vitro and in vivo studies. In the present study was modifying effect of SRA on 7,12-dimethylbenz(a)anthracene (DMBA) induced cell surface glycoconjugates (GCs ...
Velu Periyannan, Vinothkumar Veerasamy
doaj   +1 more source

Formulation and evaluation of a mucoadhesive buccal tablet of mefenamic acid

Brazilian Journal of Pharmaceutical Sciences, 2020
Buccal route of administration has many advantages such as improving patient compliance, bypassing the GIT and hepatic first pass effect. The objectives are to formulate mucoadhesive buccal tablet using Mefenamic acid and compatible excipients, and to ...
Karen Lu Li, Agnes Llamasares Castillo
doaj   +1 more source

A mussel-inspired film for adhesion to wet buccal tissue and efficient buccal drug delivery

Nature Communications, 2021
Administration of drugs via the buccal route has attracted much attention in recent years. However, developing systems with satisfactory adhesion under wet conditions and adequate drug bioavailability still remains a challenge.
Shanshan Hu, Xibo Pei, Lunliang Duan, Zhou Zhu, Yanhua Liu, Junyu Chen, Tao Chen, Ping Ji, Qianbing Wan, Jian Wang   +9 more
doaj   +1 more source

Development and Characterization of Mucoadhesive Film of Nitrendipine for Buccal Administration

International Journal of Nano Studies & Technology, 2013
Mucoadhesive buccal patches containing nitrendipine were prepared using the solvent casting method. Chitosan was used as bio-adhesive polymer and different ratios of chitosan to PVP K-30 were used. The pre-formulation study using DSC revealed the compatibility of drug and polymer.
Chauhan N, Mittal A, U.K.Bajaj
openaire   +1 more source

How Intuitive Is the Administration of Pediatric Emergency Medication Devices for Parents? Objective Observation and Subjective Self-Assessment

Pharmacy
Background: to assess the intuitiveness of parents’ administration of pediatric emergency devices (inhalation, rectal, buccal, nasal, and auto-injector).
Ruth Melinda Müller, Birthe Herziger, Sarah Jeschke, Martina Patrizia Neininger, Thilo Bertsche, Astrid Bertsche   +5 more
doaj   +1 more source

Preparation and Characterization of a Novel Mucoadhesive Carvedilol Nanosponge: A Promising Platform for Buccal Anti-Hypertensive Delivery

Gels, 2022
Carvedilol (CRV) is a non-selective third generation beta-blocker used to treat hypertension, congestive heart failure and angina pectoris. Oral administration of CRV showed poor bioavailability (25%), which might be ascribed to its extensive first-pass ...
El-Sayed Khafagy, Amr S. Abu Lila, Nahed Mohamed Sallam, Rania Abdel-Basset Sanad, Mahgoub Mohamed Ahmed, Mamdouh Mostafa Ghorab, Hadil Faris Alotaibi, Ahmed Alalaiwe, Mohammed F. Aldawsari, Saad M. Alshahrani, Abdullah Alshetaili, Bjad K. Almutairy, Ahmed Al Saqr, Shadeed Gad   +13 more
doaj   +1 more source

Development and Characterization of Inkjet Printed Edible Films for Buccal Delivery of B-Complex Vitamins

Pharmaceuticals, 2020
Buccal films containing two vitamins, i.e., thiamine hydrochloride (THCl) and nicotinic acid (NA), were fabricated via two-dimensional (2D) inkjet printing.
Georgios Eleftheriadis, Paraskevi Kyriaki Monou, Eleftherios Andriotis, Elisavet Mitsouli, Nikoleta Moutafidou, Catherine Markopoulou, Nikolaos Bouropoulos, Dimitrios Fatouros   +7 more
doaj   +1 more source