Results 61 to 70 of about 27,341 (167)

Overcoming the clinical challenges of traditional ayahuasca: a first-in-human trial exploring novel routes of administration of N,N-Dimethyltryptamine and harmine

Frontiers in Pharmacology, 2023
Recently, the Amazonian plant medicine “ayahuasca”—containing the psychedelic compound N,N-dimethyltryptamine (DMT) and numerous β-carboline alkaloids, such as harmine—has been suggested to exhibit beneficial effects in patients with affective and other ...
Dario A. Dornbierer, Dario A. Dornbierer, Dario A. Dornbierer, Laurenz Marten, Laurenz Marten, Jovin Mueller, Helena D. Aicher, Helena D. Aicher, Helena D. Aicher, Michael J. Mueller, Michael J. Mueller, Michael J. Mueller, Martina Boxler, Michael Kometer, Davor Kosanic, Robin von Rotz, Maxim Puchkov, Thomas Kraemer, Hans-Peter Landolt, Hans-Peter Landolt, Erich Seifritz, Erich Seifritz, Milan Scheidegger, Milan Scheidegger   +23 more
doaj   +1 more source

Preparation and Characterization of Polymeric Mucoadhesive Film for Buccal Administration [PDF]

British Journal of Pharmaceutical Research, 2014
Objectives: Buccal films consist mainly of polymer that has a good mucoadhesive profile and plasticizer. A lot of polymers and plasticizers can be used to configure the mucoadhesive films as hydroxyethyl cellulose and glycerin respectively. Material and Methods: Films prepared by dispersing the polymer, mixing it with plasticizer and pouring it in ...
Ramy Gales
openalex   +3 more sources

Amlodipine-induced buccal lichenoid lesions: A case report [PDF]

Malaysian Family Physician
Buccal lichenoid lesions (BLLs) are characterised by a unique, linear whitish striation in the buccal region and can be accompanied by ulcers, plaques, erythemas, atrophies and blisters.
Muhammad Hafiz Mohamed Pauzi, Azidah Abdul Kadir, Zainab Mat Yudin   +2 more
doaj   +1 more source

Development of a Mucoadhesive Vehicle Based on Lyophilized Liposomes for Drug Delivery through the Sublingual Mucosa

Pharmaceutics, 2022
A pharmaceutical vehicle based on lyophilized liposomes is proposed for the buccal administration of drugs aimed at systemic delivery through the sublingual mucosa. Liposomes made of egg phosphatidylcholine and cholesterol (7/3 molar ratio) were prepared
María José De Jesús Valle, Aranzazu Zarzuelo Castañeda, Cristina Maderuelo, Alejandro Cencerrado Treviño, Jorge Loureiro, Paula Coutinho, Amparo Sánchez Navarro   +6 more
doaj   +1 more source

Design, development, and optimization of mucoadhesive buccal films of ganaxolone for enhanced bioavailability

Journal of Applied Pharmaceutical Research
Background: CDD disorder affects children mainly during their first three months of life. The buccal route offers advantages over oral administration for ganaxolone by avoiding first-pass metabolism and providing direct systemic absorption.
Onkar Pawar, Rahul Godge, Ganesh Shinde, Kailas Barde, Akshay Vikhe   +4 more
doaj   +1 more source

Peptide KSL-W-Loaded Mucoadhesive Liquid Crystalline Vehicle as an Alternative Treatment for Multispecies Oral Biofilm

Molecules, 2015
Decapeptide KSL-W shows antibacterial activities and can be used in the oral cavity, however, it is easily degraded in aqueous solution and eliminated. Therefore, we aimed to develop liquid crystalline systems (F1 and F2) for KSL-W buccal administration ...
Jéssica Bernegossi, Giovana Maria Fioramonti Calixto, Paulo Ricardo da Silva Sanches, Carla Raquel Fontana, Eduardo Maffud Cilli, Saulo Santesso Garrido, Marlus Chorilli   +6 more
doaj   +1 more source

Comparative bioavailability study following a single dose intravenous and buccal administration of remdesivir in rabbits. [PDF]

Int J Pharm, 2022
Szente L, Renkecz T, Sirok D, Stáhl J, Hirka G, Puskás I, Sohajda T, Fenyvesi É.   +7 more
europepmc   +1 more source

Buccal versus buccal palatal infiltration for pulpal anesthesia using 2% lidocaine and 4% articaine: A randomized controlled trial

Journal of Oral Biology and Craniofacial Research
Background: The inability in achieving complete pulpal anesthesia with standard buccal infiltration especially in cases with SIP used for maxillary teeth.
Umesh Kumar, Nikita Garg, Ruchi Vashisht, Amrita Kumari, Charan Kamal Kaur, Akhil Rajput   +5 more
doaj   +1 more source

A mini-review on drug delivery through wafer technology: Formulation and manufacturing of buccal and oral lyophilizates

Journal of Advanced Research, 2019
A great number of patients have difficulty swallowing or needle fear. Therefore, buccal and orodispersible dosage forms (ODFs) represent an important strategy to enhance patient compliance. Besides not requiring water intake, swallowing or needles, these
Juliana Souza Ribeiro Costa, Karen de Oliveira Cruvinel, Laura Oliveira-Nascimento   +2 more
doaj   +1 more source

An experimental model of chemically-induced ulceration of the buccal mucosa of Mus musculus

Makara Journal of Health Research, 2019
Background: Ulceration caused by chemical agents used in dental practice for in-office or home-used is a common event, resulting in discomfort and pain.
Erik Idrus, Pratiwi Dwi Hartanti, Dewi Fatma Suniarti, Sri Redjeki Prasetyo, Yuniardini Septorini Wimardhani, Ajiravudh Subarnbhesaj   +5 more
doaj   +1 more source