Results 71 to 80 of about 2,104,096 (377)

BUCCAL FILM: A NOVEL APPROACH FOR ORAL MUCOSAL DRUG DELIVERY SYSTEM [PDF]

, 2021
Buccal drug delivery especially refers to the delivery of drugs through the buccal mucosal membrane lining of the oral cavity. For geriatric and pediatric patients who undergo difficulties in swallowing conventional oral solid dosage forms, the buccal ...
BAIG, REESHA, HAJU, SHIFA, SAWANT, GAURANG, YADAV, SHEELA   +3 more
core   +1 more source

To Compare the Efficacy of Preoperative Oral Medication of Ibuprofen and Ketorolac on Anesthetic Efficacy of Maxillary Buccal Infiltration Using Buffered 2% Lidocaine with 1:100,000 Adrenaline with Irreversible Symptomatic Pulpitis: A Prospective Clinical Study [PDF]

Dental Journal of Advance Studies
Aim: To assess the effects of ibuprofen and ketorolac, two preoperative oral medications on the effectiveness of anesthesia for maxillary buccal infiltration with buffered 2% lidocaine and 1:100,000 adrenaline in patients with irreversible symptomatic ...
Neha Menrai, Sameer Makkar, Sandeep Gupta, Ajay Aryan, Chetna Tarnach   +4 more
doaj   +1 more source

Advanced Technologies for Oral Controlled Release: Cyclodextrins for oral controlled release [PDF]

, 2011
Cyclodextrins (CDs) are used in oral pharmaceutical formulations, by means of inclusion complexes formation, with the following advantages for the drugs: (1) solubility, dissolution rate, stability and bioavailability enhancement; (2) to modify the drug ...
A Al-Omar, A Latrofa, A Miro, A Trapani, A Vyas, AC Jain, AK Upadhyay, AL Nielsen, AS Hoffman, B Haeberlin, B Pose-Vilarnovo, BN Naidu, C Cannavà, C Rodriguez-Tenreiro, C Rupp, C-Y Chen, Catarina Carvalho, Claúdia Conduto, CM Buchanan, CM Fernandes, D Duchêne, D Duchêne, EA Zannou, EY Kim, F Frézard, F Hirayama, G Corti, G Gladys, G Pescitelli, G Trapani, G Wenz, G Zingone, GL Amidon, H Blode, H Hamada, H Matsuda, H Namazi, H Taira, H Yano, HA Archontaki, Helena M. Cabral Marques, HH Sigurdsson, HS Ganapathy, HS Woldum, Inês Sanches, IV Terekhova, J Cheng, J Králová, J Savolainen, J Szejtli, J Szejtli, J Xiong, JJ García-Rodriguez, João Arrais, JP Venter, JR Moyano, JS Smith, JW Wong, K Dua, K Minami, K Motoyama, K Nakanishi, K Okimoto, K Okimoto, K Okimoto, K Terao, K Udo, K Uekama, K Uekama, K Uekama, K-H Frӧmming, KP Chowdary, L Ribeiro, L Szente, L Trichard, M Agüeros, M Agüeros, M Charoenchaitrakool, M Cirri, M Echezarreta-López, M Fukuda, M Jug, M Jug, M Kamada, M Prabaharan, M Roux, M Sauceau, M Temtem, M Türk, M Usuda, M Yoshinari, M-J Zou, ME Zugasti, MT Esclusa-Díaz, MZI Khan, N Mourtzis, N Patel, N Zerrouk, N Zhang, N Özdemir, P Jansook, P Mura, P Mura, P Mura, P Mura, P Mura, Patrícia Pontes, Paulo José Salústio, PJ Salústio, R Cavalli, R Cavalli, R Challa, R Ficarra, R Garg, R Stancanelli, RL Carrier, S Petralito, S Péroche, S Sajeesh, S Sotthivirat, S Sotthivirat, S Szejtli, S Tommasini, S-Y Lee, Shishu, SM Badr-Eldin, T Endo, T Higashi, T Higashi, T Irie, T Loftsson, T Loftsson, T Loftsson, T Vasconcelos, T Yamanoi, V Burckbuchler, V Lemesle-Lamache, VM Rao, W Ling, W Sajomsang, X Lu, X Wen, X-M Liu, Y He, Y Ikeda, Y Ikeda, Y Liu, Y Liu, Y Lu, Y Tozuka, Y Zhou, Y-Z Du, Z Lu, Z Wang   +153 more
core   +1 more source

Comparative Evaluation of Alveolar Nerve Block with 2% Lidocaine–Epinephrine and 4% Articaine–Epinephrine Buccal Infiltration in Mandibular Premolar and Molar Region in Children: A Double-Blind, Randomized Trial

Children
Background/Objectives: Effective pain control in pediatric dentistry combines behavior management, local anesthesia, and follow-up care. This study compared the efficacy of inferior alveolar nerve block (IANB) with 2% lidocaine and epinephrine versus ...
Jelena Komsic, Sanja Vujkov, Isidora Neskovic, Duska Blagojevic, Ana Tadic, Bojan Petrovic, Branislav Bajkin   +6 more
doaj   +1 more source

Drug Bioavailability Enhancing Agents of Natural Origin (Bioenhancers) that Modulate Drug Membrane Permeation and Pre-Systemic Metabolism

Pharmaceutics, 2019
Many new chemical entities are discovered with high therapeutic potential, however, many of these compounds exhibit unfavorable pharmacokinetic properties due to poor solubility and/or poor membrane permeation characteristics. The latter is mainly due to
Bianca Peterson, Morné Weyers, Jan H. Steenekamp, Johan D. Steyn, Chrisna Gouws, Josias H. Hamman   +5 more
doaj   +1 more source

Impact of Whole Plant Extract of Pergularia daemia on Glycoproteins in Dimethylbenz(A)Anthracene Induced Hamster Buccal Pouch Carcinogenesis [PDF]

Avicenna Journal of Medical Biochemistry, 2018
Background: Oral squamous cell carcinoma is a major component of a diverse group of neoplasms often referred to as ‘head and neck cancer’. Frequent smoking and/or alcohol consumption are two major risk factors for oral cancer.
Vaithiyanathan Veluchamy, Mirunalini Sankaran   +1 more
doaj   +1 more source

Cholinergic suppression: A postsynaptic mechanism of long-term associative learning [PDF]

, 1986
Food avoidance learning in the mollusc Pleurobranchaea entails reduction in the responsiveness of key brain interneurons in the feeding neural circuitry, the paracerebral feeding command interneurons (PCNs), to the neurotransmitter acetylcholine (AcCho).
Davis, W. Jackson, Kovac, Mark P., Matera, Eugene M., McCormack, Kenneth J., Morielli, Anthony D., Shrum, Richard G.   +5 more
core   +2 more sources

Buccal Thin Films as Potent Permeation Enhancers for Cytisine Transbuccal Delivery

Membranes, 2022
Cytisine (CYT) is a powerful anti-smoking compound which could greatly benefit from transbuccal delivery because of both its unfavorable pharmacokinetics after oral administration and its intrinsic ability to permeate the buccal mucosa. This work aims to
Viviana De Caro, Giuseppe Angellotti, Fabio D’Agostino, Giulia Di Prima   +3 more
doaj   +1 more source

Silodosin oral films: Development, physico-mechanical properties and in vitro dissolution studies in simulated saliva [PDF]

, 2019
Sublingual film dosage forms for drugs used for fast symptomatic treatment have promise because they allow a rapid onset of action. The aim of this study was to prepare films of silodosin intended for sublingual administration for the symptomatic ...
Adair, Alhayali, Allam, Alonzo, Boateng, Brady, Brouwers, Campisi, Chapple, Curatolo, De Caro, El-Setouhy, ElMeshad, Gao, Garsuch, Gittings, Guo, Hanif, Hobbs, Huang, Humphrey, Jug, Kalia, Kapoor, Kim, Koland, Korhonen, Li, Liew, Madhav, Mashru, Matsubara, Miller-Chou, Montorsi, Nagy, Patel, Prabhu, Prasad, Preis, Preis, Preis, Radebaugh, Repka, Rossi, Runja, Sharma, Singh, Singh, Singh, Singh, Slavkova, Tanno, Vila, Visser, Vuddanda, Vuddanda, Yang, Zhang   +57 more
core   +1 more source

Buccal, intranasal or intravenous lorazepam for the treatment of acute convulsions in children in Malawi: An open randomized trial

African Journal of Emergency Medicine, 2015
Acute convulsions in children are a common emergency worldwide. Benzodiazepines are the recommended first line treatment. Intravenous lorazepam is inexpensive, long acting and the first line drug in resource-rich settings. However, comparable efficacy by
Samantha Lissauer, Julia Kenny, Oliver Jefferis, Tom Wingfield, Anne Miller, George Chagaluka, Linda Kalilani-Phiri, Elizabeth Molyneux   +7 more
doaj   +1 more source