Results 121 to 130 of about 2,728 (262)

Population Pharmacokinetic and Exposure‐Efficacy Analysis of Baloxavir Marboxil for Influenza Treatment and Post‐Exposure Prophylaxis in Children

Clinical Pharmacology &Therapeutics, EarlyView.
Baloxavir acid (baloxavir), the active metabolite of the prodrug baloxavir marboxil, is a selective inhibitor of the influenza virus cap‐dependent endonuclease. The population pharmacokinetic (popPK) profile of baloxavir in adults/adolescents has been described previously.
Sylvie Retout, Stefan De Buck, Jacques Gaudreault, Sébastien Jolivet, Vincent Duval, Valérie Cosson, Marie‐Laure Delporte   +6 more
wiley   +1 more source

Measuring the Impact of the Substitution of Innovator Biologics With Biosimilars on Uptake and Costs Among Ontario Public Drug Benefit Recipients

Clinical Pharmacology &Therapeutics, EarlyView.
In Ontario, biologics have historically represented a small proportion of public drug claims but a large proportion of spending. Biosimilars, lower cost alternatives to biologics, offer a potential solution to the rising spending on biologics. From March 2023 to January 2024, the Ontario Ministry of Health required public drug program beneficiaries on ...
Anita Iacono, Martin K. H. Ho, Joanna Yang, Tonya Campbell, William Wynne, Dana Shearer, Lene Andersen, Eric Majer, Shaleesa Ledlie, Mina Tadrous, Tara Gomes   +10 more
wiley   +1 more source

Temperature control board design and validation for skipper-CCD sensors using a buck converter. [PDF]

HardwareX
Barrientos M, Barrientos M, Rodas J, Renault A, Romero C, Palacios F, Chavez C, Botti AM.   +7 more
europepmc   +1 more source

Does Institutional Ownership Structure Reduce Greenhouse Gas Emissions? An In‐Depth Study of Corporations Social Responsibility of European‐Listed Firms

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Motivated by the growing attention and concerns surrounding climate change and the potential role of institutional investors' ownership concentration (OC) in reducing corporations' greenhouse gas (GHG) emissions, this article explores the relationship between various forms of institutional ownership and firms' GHG emission intensity. To do so,
Daniele Giordino, Elisa Ballesio, Aradhana Galgotia, Laura Broccardo   +3 more
wiley   +1 more source

Online Inductance Monitoring Based on Dynamic Characteristics and ESR Effect Compensation for Buck Converter Without Current Sensor. [PDF]

Sensors (Basel)
Chen C, Wang L, Wang W, Min R, Tong Q.
europepmc   +1 more source

A novel buck-boost converter

, 2017
In this paper, a novel buck-boost converter with the voltage gain of 2?1/1? is proposed. Output voltage is positive and the voltage stresses on the power switches and the diodes are low. Suggested topology is based on conventional boost converter. Proposed converter can provide a large step down voltage conversion ratio.
Abut, Nurettin, Kandilli, İsmet
openaire   +1 more source

Strengthening urban resilience in China through underground infrastructures management: Addressing global climate challenges with technological solutions

Deep Underground Science and Engineering, EarlyView.
This paper explores how climate‐resilient technologies, such as smart grids, digital twins, and self‐healing materials, can enhance urban resilience. It highlights the urgent need for proactive planning, public‐private collaboration, and data‐driven innovation to future‐proof underground infrastructure amid accelerating climate and urban pressures ...
Kai Chen Goh, Tonni Agustiono Kurniawan, Christia Meidiana, Abdelkader Anouzla, Faissal Aziz, Imran Ali, Joan Cecilia C. Casila, M. Imran Khan, Dongdong Zhang, Meihui Jiang, Mohd Hafiz Dzarfan Othman, Md Munir Hayet Khan, Kasun Kumara Dissanayake   +12 more
wiley   +1 more source

The Prevention of Eating Disorders in Australian Adolescents: A Modeled Cost‐Effectiveness Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Prevention programs for eating disorders (EDs) have the potential to reduce the onset of these diseases and improve the mental health and well‐being of the general population. However, there is mixed evidence on whether routine implementation of such programs at the population level is cost‐effective.
Long Khanh‐Dao Le, Eng Joo Tan, Phillipa Hay, Jaithri Ananthapavan, Yong Yi Lee, Cathrine Mihalopoulos   +5 more
wiley   +1 more source

Experimental evaluation of DC-DC buck converter based on adaptive fuzzy fast terminal synergetic controller. [PDF]

Sci Rep
Anane Z, Babes B, Hamouda N, Benaouda OF, Alotaibi S, Alzahrani T, Aeggegn DB, Ghoneim SSM.   +7 more
europepmc   +1 more source

Facet‐Tailored Co3O4 as Electronic Regulator and Stabilizing Support for Ru Nanocluster: Toward Efficient Alkaline HER

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Facet‐engineered Ru@Co3O4 nanosheets precisely anchor Ru nanoclusters on the Co3O4 (111) facets, optimizing the hydrogen‐bond network of interfacial water and downshifting the Ru d‐band center. The Ru@Co3O4 NSs show outstanding HER activity and long‐term durability in AEMWE devices. This work demonstrates a crystal facet engineering strategy to develop
Jia Wang, De Wang, Zhenyu He, Mengyu Yan, Yinyu Xiang, Huipeng Li, Lina Xu, Junsheng Li   +7 more
wiley   +1 more source