Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu +12 more
wiley +1 more source
Optimization of the grid-stiffened structure via PSO-LSSVR surrogate modeling and sensitivity analysis. [PDF]
Gai J +5 more
europepmc +1 more source
Marine silicon for biomedical sustainability
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han +3 more
wiley +1 more source
Multiscale Compressive Failure Analysis of Wrinkled Laminates Based on Multiaxial Damage Model. [PDF]
Shi J +6 more
europepmc +1 more source
Bottom‐up Strategies for Generating Polymer Protocells That Mimic Cellular Communication
This review focuses on polymeric protocells produced using a bottom‐up approach. Polymer‐based assemblies guarantee stability and designability by adjusting the properties of the amphiphilic copolymers used. The review covers protocell architectures, production, and their intra‐ and intercellular communication mechanisms.
Gloria Saorin +3 more
wiley +1 more source
Multi-Parameter Modulation of Dirac Plasmons in Germanene via Doping and Strain: A DFT Insight. [PDF]
Li P, Han L, Zhang L, Hui N.
europepmc +1 more source
ABSTRACT The homeostatic cortical actin array in plant cells plays important roles in fundamental processes, including intracellular transport, secretion, cell expansion, and cytoplasmic streaming. In response to diverse chemical and mechanical signals, the cortical array can remodel within minutes to assume new configurations or altered filament ...
June Hyung Kim +4 more
wiley +1 more source
Quantifying Inter-Ply Friction and Clamping Effects via an Experimental-Numerical Framework: Advancing Non-Coherent Deformation Control of Uncured Metal-Fiber-Reinforced Polymer Laminates. [PDF]
Chen Y, Liu S.
europepmc +1 more source
Numerical investigation of steel-casing opening design for penetration through riprap in a macro-tidal estuarine mudflat. [PDF]
Qin Z +10 more
europepmc +1 more source

