Results 121 to 130 of about 352,185 (244)

Understanding extracellular vesicles in antiaging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad   +3 more
wiley   +1 more source

Loss, persistence and reversal of phenotypic traits

open access: yesBiological Reviews, Volume 101, Issue 5, Page 2119-2133, October 2026.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni   +4 more
wiley   +1 more source

Modeling the START transition in the budding yeast cell cycle.

open access: yesPLoS Computational Biology
Budding yeast, Saccharomyces cerevisiae, is widely used as a model organism to study the genetics underlying eukaryotic cellular processes and growth critical to cancer development, such as cell division and cell cycle progression. The budding yeast cell
Janani Ravi   +2 more
doaj   +1 more source

Multifaceted Suppression of Staphylococcal Virulence Phenotypes: In Vitro Study of a Cellular Status With Reduced Agr Activity and Impaired Biofilm

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Finding of in vitro S. aureus status with reduced Agr activity and impaired biofilm. ABSTRACT Anti‐quorum sensing (QS) therapy has been focused on to reduce the virulence of pathogenic bacteria. However, there is a risk that suppression of the staphylococcal QS Agr system might promote biofilm formation.
Nghi Bao Nguyen   +4 more
wiley   +1 more source

The Sleeping Giant: Metabolism and Autophagy in the Generation and Survival of Dormant Polyploid Giant Cancer Cells

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Polyploid giant cancer cells (PGCCs) arise in response to stress and play a critical role in therapy resistance and tumor dormancy. These cells can evade conventional treatments and later contribute to cancer relapse by generating progeny through nonmitotic, amitotic mechanisms.
Silvia Guil‐Luna   +3 more
wiley   +1 more source

The role of protein kinases in DNA replication in Saccharomyces cerevisiae [PDF]

open access: yes, 2010
The initiation of DNA replication at the onset of S phase in eukaryotic cells is a critically important and tightly regulated process. Multiple origins of replication in the genome must be co-ordinately regulated such that duplication of the chromosomes ...
Sweet, S.
core  

Mucosal‐Associated Invariant T Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao   +5 more
wiley   +1 more source

Time-series of HXT-GFP expression in budding yeast

open access: yes
Cells can match expression of a series of genes to a signal, so that each gene expresses in a particular range of the signal. An example is glucose transport in budding yeast where cells express different hexose-transporter (\g{HXT}) genes in different ...
Montano-Gutierrez, Luis Fernando   +1 more
core   +1 more source

Regulatory Graph for Budding Yeast.

open access: yes, 2013
Regulatory Graph for Budding Yeast.
Robert G. Todd (304593)   +1 more
core   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 10, Page 1648-1661, October 2026.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta   +5 more
wiley   +1 more source

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