Results 171 to 180 of about 352,185 (244)

Modeling and simulation of cell cycle in budding yeast

open access: yes, 2004
The molecular machinery of the cell cycle is known in detail for the budding yeast, Saccharomyces cerevisiae. In spite of its evolutionary distance from other complex organisms, the budding yeast cell cycle has many features which are similar to complex ...
Mandar Chitre.
core  

The revised three-step detour pathway in dolichol biosynthesis is evolutionarily conserved in budding yeast. [PDF]

open access: yesProc Natl Acad Sci U S A
Hanaoka K   +5 more
europepmc   +1 more source

Synthetic Chromosomes in Yeast: A Platform for Understanding and Programming Eukaryotic Life

open access: yesMicrobial Biotechnology, Volume 19, Issue 9, September 2026.
Early technical advances established yeast as a platform for cloning, assembling and maintaining large DNA molecules, culminating in the construction of synthetic yeast chromosomes. These synthetic chromosomes now allow researchers to test how chromosome content and architecture shape cellular function.
Daniel T. Lusk, Ian M. Ehrenreich
wiley   +1 more source

Expanding the Genetic Toolkit of Pichia kudriavzevii E1 for Enhanced Mycoprotein Production

open access: yesMicrobial Biotechnology, Volume 19, Issue 9, September 2026.
A library of endogenous promoters with a 455‐fold activity range was developed using an established episomal expression vector in the Pichia kudriavzevii E1 strain. The promoter library was used to regulate genes associated with nitrogen assimilation and pyruvate metabolism to enhance mycoprotein production.
Yupeng Wang   +7 more
wiley   +1 more source

A Mechanism‐Based Framework for Anti‐Aging Strategies: From Metabolic Regulation to Senotherapy and Stem Cell‐Based Interventions

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
The aging of the human body is a complex process driven by multiple contributing factors. Based on their underlying mechanisms, current anti‐aging interventions can be classified into six primary categories. This paper summarizes the most promising anti‐aging strategies within each class. ABSTRACT The global prevalence of aging and age‐related diseases
Feifei Li   +4 more
wiley   +1 more source

A minimal model for the role of Rim4 in regulating meiotic exit in budding yeast. [PDF]

open access: yesMol Biol Cell
Marquez Davila VA   +6 more
europepmc   +1 more source

Proteostasis of organelles in aging and disease

open access: yesThe FEBS Journal, Volume 293, Issue 18, Page 5600-5626, September 2026.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi   +5 more
wiley   +1 more source

Love-thy-neighbor: neural networks for tracking and lineage tracing in budding yeast. [PDF]

open access: yesBioinform Adv
Zelic M   +11 more
europepmc   +1 more source

Homologous recombination mutants cause differing lethality between h− and h+ Schizosaccharomyces pombe strains due to mat1 heterochromatin

open access: yesThe FEBS Journal, Volume 293, Issue 17, Page 5205-5220, September 2026.
Homologous recombination (HR) in Schizosaccharomyces pombe is essential when mating‐type switching–induced double‐strand breaks (DSBs) form at the mat1 locus. In h90 and h− strains, efficient mat1 DSB formation renders HR indispensable unless suppressors block these breaks.
Peter Kolesar   +3 more
wiley   +1 more source

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