Results 211 to 220 of about 1,411,488 (286)
Missense Variants in the Second Transmembrane Domain of TMEM17 Disrupt Its Stability and Function and Lead to a Wide Phenotypic Spectrum of Ciliopathies
Clinical Genetics, Volume 109, Issue 2, Page 305-315, February 2026.Missense variants in TMEM17 disrupt its localization and function at the ciliary transition zone, leading to a wide range of ciliopathy phenotypes, from OFD6 and Joubert syndromes to Meckel syndrome. ABSTRACT
Ciliopathies are rare genetic disorders characterized by significant genetic and phenotypic variability.Lucile Boutaud, Chunmei Li, Candice Moncler, Laure Verlin, Meriem Garfa‐Traoré, Nicolas Bourgon, Dhruvin Akbari, Jeanne Porée, Valentina Serpieri, Marine Panza, Lynda Haddad, Patrick Nitschké, Jacqueline Aziza, Cristina Matt, Enza Maria Valente, Patricia Gargallo, Charlotte Dubucs, Tania Attié‐Bitach, Michel R. Leroux, Sophie Thomas +19 morewiley +1 more sourceVulnerability of marine megafauna to global at‐sea anthropogenic threats
Conservation Biology, Volume 40, Issue 1, February 2026.Abstract
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened ...Michelle VanCompernolle, Juliet Morris, Hannah J. Calich, Jorge P. Rodríguez, Sarah A. Marley, Jessica R. Pearce, Briana Abrahms, Katya Abrantes, André S. Afonso, Alex Aguilar, Andrews Agyekumhene, Tomonari Akamatsu, Susanne Åkesson, Nyimale G. Alawa, Joanna Alfaro‐Shigueto, R. C. Anderson, Tycho Anker‐Nilssen, Javier A. Arata, Gonzalo Araujo, Martin C. Arostegui, Haritz Arrizabalaga, Lucy M. Arrowsmith, Marie Auger‐Méthé, Isabel C. Avila, Fred Bailleul, Joanna Barker, Dawn R. Barlow, Adam Barnett, Hector Barrios‐Garrido, Alastair M. M. Baylis, Giovanni Bearzi, Lars Bejder, Eduardo J. Belda, Scott R. Benson, Michael L. Berumen, Sophie Bestley, Natalia P. A. Bezerra, Antonin V. Blaison, Lars Boehme, Steven J. Bograd, Bolaji Dunsin Abimbola, Mark E. Bond, Asunción Borrell, Phil J. Bouchet, Peter Boveng, Gill Braulik, Camrin D. Braun, Stephanie Brodie, Leandro Bugoni, Carlos Bustamante, Steven E. Campana, Susana Cárdenas‐Alayza, Ruth H. Carmichael, Gemma Carroll, Matt I. D. Carter, Filipe R. Ceia, Salvatore Cerchio, Luciana C. Ferreira, Philippine Chambault, Taylor K. Chapple, Patricia Charvet, Elpis J. Chavez, Damien Chevallier, Andre Chiaradia, B. Louise Chilvers, Megan A. Cimino, Bethany L. Clark, C. R. Clarke, Thomas A. Clay, Carl S. Cloyed, Jesse E. M. Cochran, Tim Collins, Enric Cortes, Eduardo Cuevas, David J. Curnick, Peter Dann, P. J. Nico de Bruyn, Asha de Vos, Solène Derville, Maria P. Dias, Bruno Diaz‐Lopez, Kara L. Dodge, Alistair D. M. Dove, Thomas K. Doyle, J. Marcus Drymon, Christine L. Dudgeon, Peter H. Dutton, Ursula Ellenberg, Simon H. Elwen, Louise Emmerson, Edem A. Eniang, Mario Espinoza, Nicole Esteban, Evert Mul, Brian S. Fadely, Annette L. Fayet, Chris Feare, Steven H. Ferguson, Laura Joan Feyrer, Brittany Finucci, Katie R. N. Florko, Jorge Fontes, C. M. Fortuna, Sabrina Fossette, Leila Fouda, Esteban Frere, Mariana M. P. B. Fuentes, Austin J. Gallagher, Pablo Garcia Borboroglu, Claire Garrigue, Pauline Gauffier, Enrico Gennari, Tilen Genov, Elitza S. Germanov, Joan Giménez, Matthew H. Godfrey, Brendan J. Godley, Simon D. Goldsworthy, Matthew Gollock, Victoria González Carman, Natasha J. Gownaris, W. James Grecian, Hector M. Guzman, Mark Hamann, Neil Hammerschlag, Erpur S. Hansen, Mike P. Harris, Gordon Hastie, Danielle E. Haulsee, Elliott L. Hazen, Mads Peter Heide‐Jørgensen, Elizabeth E. Hieb, Jeff W. Higdon, Mark A. Hindell, Jefferson T. Hinke, Xavier Hoenner, G. J. Greg Hofmeyr, Bonnie J. Holmes, Erich Hoyt, Luis A. Huckstadt, Nigel E. Hussey, Charlie Huveneers, Lyn G. Irvine, Rima W. Jabado, David M. P. Jacoby, Audrey Jaeger, Patrick M. Jagielski, Mark Jessopp, Oliver J. D. Jewell, David Jiménez Alvarado, Lance K. B. Jordan, Salvador J. Jorgensen, Benjamin Kahn, Alexandros A. Karamanlidis, Akiko Kato, Lucy W. Keith‐Diagne, M. S. Kiani, Jeremy J. Kiszka, Alison A. Kock, R. Keller Kopf, Carey Kuhn, Peter M. Kyne, Kristin L. Laidre, Fernanda O. Lana, Michelle E. Lander, Matthieu Le Corre, Olivia A. Lee, Ruth H. Leeney, Alexis L. Levengood, J. Jacob Levenson, Marcela Libertelli, Kwang‐Ming Liu, Milagros Lopez Mendilaharsu, Alexandra Loveridge, Christopher G. Lowe, Heather J. Lynch, Bruno C. L. Macena, Alice I. Mackay, Jeffry Madrigal‐Mesén, Mark L. Mallory, Jeffrey C. Mangel, Katherine L. Mansfield, David March, Marianne Marcoux, Helene Marsh, A. D. Marshall, Thomas Mattern, Sara M. Maxwell, Rebecca L. McGuire, Lachlan McLeay, Clive R. McMahon, Séverine Methion, Eva K. M. Meyers, Candice Michelot, Cara Masere, Gianna Minton, Benjamin Morales‐Vela, Gonzalo Mucientes, Hilario Murua, M. A. C. Nicoll, Yuri Niella, Giuseppe Notarbartolo di Sciara, Steffen Oppel, Florian Orgeret, Julie N. Oswald, Ellie Owen, Nathan Pacoureau, Vitor H. Paiva, Daniel M. Palacios, Simone Panigada, Yannis P. Papastamatiou, Guido J. Parra, Sylvia K. Parsons, Donna L. Patterson‐Fraser, S. Hoyt Peckham, Stephen D. Petersen, Lorien Pichegru, Simon J. Pierce, Tânia Pipa, Enrico Pirotta, Pierre Pistorius, Riley A. Pollom, Rui Prieto, Laura Prosdocimi, Klemens Pütz, Nuno Queiroz, John L. Quinn, Jaime A. Ramos, Holly C. Raudino, Angela Recalde‐Salas, ALan F. Rees, Richard D. Reina, Ryan R. Reisinger, Samantha D. Reynolds, Anthony James Richardson, Nicholas G. Riddoch, Federico G. Riet‐Sapriza, James R. Robbins, David P. Robinson, Airam Rodríguez, Tracey L. Rogers, Christoph A. Rohner, Daniela Rojas‐Cañizales, Kevin Ruhomaun, Chandra Salgado Kent, Katsufumi Sato, Kylie L. Scales, Meike Scheidat, Gail Schofield, Fabrizio Serena, Edy Setyawan, Scott A. Shaffer, Brendan D. Shea, Laura Shearer, Marcus Sheaves, Richard B. Sherley, George L. Shillinger, Takahiro Shimada, Mónica A. Silva, Gregory Skomal, Reyd A. Smith, Amy F. Smoothey, Alen Soldo, Emily J. Southall, Antje Steinfurth, D. Bruce Stewart, Joshua D. Stewart, Akinori Takahashi, Vikash Tatayah, Sam Thalmann, Jean‐Baptiste Thiebot, Jesús Tomás, Leigh G. Torres, P. N. Trathan, Fritz Trillmich, Kazuoki Ueda, Frederic Vandeperre, Ralph Eric Thijl Vanstreels, Marisa Vedor, Stella Villegas‐Amtmann, Lauren J. Waller, Matt Waller, Sarah Wanless, Kelly Waples, Cortney A. Watt, Mia Wege, Caroline R. Weir, Randall S. Wells, Paul J. Wensveen, Timothy D. White, Scott D. Whiting, Øystein Wiig, Natalie E. Wildermann, David N. Wiley, Jessica Lauren Williams, Rosie S. Williams, Kenady Wilson, Matthew J. Witt, Freya C. Womersley, David J. Yurkowski, Jie Zhang, Daniel P. Costa, Carlos M. Duarte, Mark G. Meekan, Rob Harcourt, David W. Sims, Graeme C. Hays, Charitha Pattiaratchi, Víctor M. Eguíluz, Ana M. M. Sequeira +309 morewiley +1 more sourceAssociation between comorbid anxiety and depression symptomatology, quality of life, social support and use of mental health services in youth from Bogota, Buenos Aires, and Lima.
J Affect DisordVilela-Estrada AL, Lazo-Porras M, Bernabe-Ortiz A, Priebe S, Bird VJ, Ariza-Salazar K, Sureshkumar DS, Godoy-Casasbuenas N, Gómez-Restrepo C, Olivar N, Madero S, Brusco LI, Diez-Canseco F. +12 moreeuropepmc +1 more sourceProtein tandem repeats that produce frameshifts can generate new structural states and functions
The FEBS Journal, Volume 293, Issue 3, Page 842-858, February 2026.We explored an alternative protein structure landscape by analyzing amino acid sequences from frameshifted tandem repeats—regions prone to frameshifts. These frameshifts, especially in short repeats, lead to more drastic changes than in non‐repetitive regions, often altering structure, function, localization, and potentially contributing to disease ...Zarifa Osmanli, Gudrun Aldrian, Jeremy Leclercq, Theo Falgarone, Santiago M. Gómez Bergna, Denis N. Prada Gori, Andrew V. Oleinikov, Ilham Shahmuradov, Andrey V. Kajava +8 morewiley +1 more source
