Protocol for isolation of lipid-laden hepatocytes from high-fat diet-fed and metabolically challenged mice. [PDF]
Ponnusamy T +2 more
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Overdose Prevention Centers and Neighborhood Commercial Activity in New York City.
Allen B +5 more
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Symmetrical pH Electrochemical Cell Coupled to Constant Potential Coulometry for Improved Sensitivity and Precision: Part 1. Fundamental Considerations. [PDF]
Nussbaum R +3 more
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Comprehensive Biophysical Profiling Evidences Self-Oligomerization of Bacterially Expressed Pc Protein. [PDF]
Zahid M +4 more
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Improvements to dark experience replay and reservoir sampling for better balance between consolidation and plasticity. [PDF]
Kobayashi T.
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The relationship between green space and myopia in children and adolescents: a systematic review and meta-analysis. [PDF]
Wang J, Sun G, Shen C, Zhu H, He Z.
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Changing the Buffer in Buffered Lidocaine
Journal of Infusion Nursing, 2022Hospitalized patients require venous access for procedures, treatments, or therapies. The use of lidocaine for pain relief during central vascular access device (CVAD) insertion is a standard of practice. Lidocaine buffered with sodium bicarbonate has been shown to provide significantly more pain relief in the sensation of pain upon injection ...
Ann, Plohal +4 more
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Biological reactions work well only within a narrow concentration range of hydrogen ions. Paradoxically, however, many of these reactions themselves generate or consume protons. Buffers are substances that undergo reversible protonation within a particular pH range and therefore maintain the concentration of hydrogen ions within acceptable limits. This
Michael R, Green, Joseph, Sambrook
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AbstractThis paper proposes a new type of molecular device that is able to act as an inverse proton sponge to slowly decrease the pH inside a reaction vessel. This makes the automatic monitoring of the concentration of pH‐sensitive systems possible. The device is a composite formed of an alkyl chloride, which kinetically produces acidity, and a buffer ...
Alibrandi, Giuseppe +3 more
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Buffer capacity of biologics—from buffer salts to buffering by antibodies
Biotechnology Progress, 2013Controlling pH is essential for a variety of biopharmaceutical process steps. The chemical stability of biologics such as monoclonal antibodies is pH‐dependent and slightly acidic conditions are favorable for stability in a number of cases. Since control of pH is widely provided by added buffer salts, the current study summarizes the buffer ...
Anne R, Karow +2 more
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