Results 51 to 60 of about 191,924 (266)

Polyamines Counteract Carbonate-Driven Proteasome Stalling in Alkaline Conditions

Biomolecules, 2020
Cancer cells tend to increase intracellular pH and, at the same time, are known to intensively produce and uptake polyamines such as spermine. Here, we show that various amines, including biogenic polyamines, boost the activity of proteasomes in a dose ...
Anna A. Kudriaeva, George A. Saratov, Alena N. Kaminskaya, Vasiliy I. Vladimirov, Petro Yu Barzilovich, Alexey A. Belogurov   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Avian response to conservation buffers in agricultural landscapes during winter

Wildlife Society Bulletin, 2014
Native herbaceous vegetation cover along row‐crop field edges (i.e., field buffers) increases breeding densities of many bird species. However, the effect of field buffers on bird species during the non‐breeding season is less understood.
Kristine O. Evans, L. Wes Burger Jr., Samuel K. Riffell, Mark D. Smith, Daniel J. Twedt, R. Randy Wilson, Shawchyi Vorisek, Catherine Rideout, Kate Heyden   +8 more
doaj   +1 more source

Optimal Buffer Allocation in Flexible Manufacturing Systems Using Genetic Algorithm and Simulation

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
Over the past few decades, buffer allocation problems have been investigated extensively. It is widely known that buffers play important roles in the manufacturing system, including preparing disruption and improving efficiency.
Suk-Jae JEONG, Hosang JUNG
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Sistemas de información geográfica y análisis espaciales: un método combinado para realizar estudios panbiogeográficos Geographic information systems and spatial analysis: a combined method for panbiogeographic studies

Revista Mexicana de Biodiversidad, 2008
Uno de los estímulos en el progreso de la biogeografía ha sido el desarrollo y aplicación de nuevas tecnologías computacionales como los sistemas de información geográfica (SIG) y una variedad de métodos estadísticos espaciales. Dentro de la biogeografía
Jonathan Liria
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Monitoring the Dilution of Buffer Solutions with Different pH Values above and below Physiological pH in Very Small Volumes

Sensors
The accurate determination of the post-dilution concentration of biological buffers is essential for retaining the necessary properties and effectiveness of the buffer to maintain stable cellular environments and optimal conditions for biochemical ...
Vinayak J. Bhat, Daniel Blaschke, Sahitya V. Vegesna, Sindy Burgold-Voigt, Elke Müller, Ralf Ehricht, Heidemarie Schmidt   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source