Results 71 to 80 of about 247,217 (307)
Background There is increasing interest in examining the influence of the built environment on physical activity. High-resolution data in a geographic information system is increasingly being used to measure salient aspects of the built environment and ...
Hall Alexander W +2 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Two-way interplays between capital buffers, credit and output: evidence from French banks [PDF]
We assess the extent to which capital buffers (the capital banks hold in excess of the regulatory minimum) exacerbate rather than reduce the cyclical behavior of credit.
Coffinet, J. +3 more
core
Uno de los estímulos en el progreso de la biogeografía ha sido el desarrollo y aplicación de nuevas tecnologías computacionales como los sistemas de información geográfica (SIG) y una variedad de métodos estadísticos espaciales. Dentro de la biogeografía
Jonathan Liria
doaj
Avian response to conservation buffers in agricultural landscapes during winter
Native herbaceous vegetation cover along row‐crop field edges (i.e., field buffers) increases breeding densities of many bird species. However, the effect of field buffers on bird species during the non‐breeding season is less understood.
Kristine O. Evans +8 more
doaj +1 more source
Optimal Buffer Allocation in Flexible Manufacturing Systems Using Genetic Algorithm and Simulation
Over the past few decades, buffer allocation problems have been investigated extensively. It is widely known that buffers play important roles in the manufacturing system, including preparing disruption and improving efficiency.
Suk-Jae JEONG, Hosang JUNG
doaj +1 more source
Polyamines Counteract Carbonate-Driven Proteasome Stalling in Alkaline Conditions
Cancer cells tend to increase intracellular pH and, at the same time, are known to intensively produce and uptake polyamines such as spermine. Here, we show that various amines, including biogenic polyamines, boost the activity of proteasomes in a dose ...
Anna A. Kudriaeva +5 more
doaj +1 more source

