Results 71 to 80 of about 191,924 (266)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Neighborhood-based PA and its environmental correlates: a GIS- and GPS based cross-sectional study in the Netherlands

open access: yesBMC Public Health, 2018
Background To improve our understanding of the neighborhood environment – physical activity (PA) relationship, it is of importance to assess associations between neighborhood environmental characteristics and neighborhood-based PA. Methods Participants’ (
Marijke Jansen   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Reconfigurable buffer mechanism in switch fabric design

open access: yesTongxin xuebao, 2012
Current research focused on the theoretic buffer size of routers.The reconfigurable buffer tried to improve the buffer utilization rate to optimize the system performance based on the on-demand design of the reconfigurable system.In fact,for current ...
Hui-qun HUANG   +3 more
doaj   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Application Of The Work Breakdown Structure In Determining Cost Buffers In Construction Schedules

open access: yesArchives of Civil Engineering, 2015
The paper presents methods of determining the location of cost buffers and corresponding contingency costs in the CPM schedule based on its work breakdown structure.
Połoński M.
doaj   +1 more source

Buffers of Milk and Buffer Value

open access: yesJournal of Dairy Science, 1927
Since buffers are considered as substances which, by their presence in solution, increase the amount of alkali or acid that must be added to catme unit change in pH, the question of their occurrence in milk would be important. Clark (1) gives the following with regard to buffers: "By buffer action, we mean the ability of a solution to resist change in ...
J.H. Buchanan, E.E. Peterson
openaire   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

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