Results 91 to 100 of about 4,193,153 (233)

Anthracyclines induce the accumulation of mutant p53 through E2F1-dependent and -independent mechanisms

, 2011
Mutant p53 frequently accumulates in cancer cells and promotes tumor cell invasion, as part of its gain of function. Its accumulation is partially due to enhanced stability, but little is known about how the mRNA levels of mutant p53 can be regulated ...
M Dobbelstein, Dobbelstein, Matthias, Bug, M., M Bug   +3 more
core   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

Space‐Time Metasurface Antenna Enabled High‐Dimensional Electromagnetic Modulation for Intrinsic Physical Layer Security

Advanced Science, EarlyView.
The concept of high‐dimensional EM modulation using the STMA for physical layer secure communication is illustrated in figure. The STMA consists of a series of programmable unit cells, with 1‐bit reconfigurable phase states (0/π). The STMA is excited by a monochromatic continuous wave (CW) at frequency fc and controlled by a field‐programmable gate ...
Xinyu Fang, Yiqing Sun, Chenfeng Yang, Siran Wang, Zheng Xing Wang, Kaixu Wang, Geng‐Bo Wu   +6 more
wiley   +1 more source

big-unibo/stink-bug: 1.0.11

<h2><a href="https://github.com/big-unibo/stink-bug/compare/1.0.10...1.0.11">1.0.11</a> (2024-03-15)</h2> <h3>Dependency updates</h3> <ul> <li><strong>deps:</strong> update dependency notebook ...
Semantic Release Bot, Chiara Forresi, Enrico Gallinucci   +2 more
core   +1 more source

COMPLEMENTING DEFICIENT BUG REPORTS WITH MISSING INFORMATION LEVERAGING NEURAL TEXT GENERATION

, 2023
Software bug reports often lack crucial information (e.g., steps to reproduce, expected behaviour), which makes bug resolution challenging. A recent study found that 78% of bug reports from open-source projects (e.g., Eclipse) contain less than 100 words
Mukherjee, Usmi
core  

Covalently Integrated Selenoviologen–N‐Heterocyclic Carbene–Pt Nanoparticles for Visible‐Light‐Driven Hydrogen Evolution

Advanced Science, EarlyView.
A covalently integrated single‐component photocatalyst is constructed by anchoring selenoviologen to platinum nanoparticles via robust N‐heterocyclic carbene ligands. The resulting Pt─C covalent bonds function dually as protective structural scaffolds and direct channels for ultrafast intramolecular electron transfer This precise interfacial ...
Wenxi He, Guoping Li, Chenjing Liu, Yu Liu, Yawen Li, Wenxin Wei, Hairui Lei, Ni Yan, Gang He   +8 more
wiley   +1 more source

Single‐Atom‐Enhanced Fully Inkjet‐Printed Electrochemical Sensor for Dopamine Detection

Advanced Science, EarlyView.
Fully inkjet‐printed paper‐based dopamine sensors are fabricated using nitrogen‐doped graphene acid functionalized with copper single atoms. The copper sites uniquely enhance dopamine oxidation through strong molecular adsorption, as verified by electrochemical measurements and DFT calculations. The approach highlights the potential of single‐atom inks
Martin‐Alex Nalepa, David Panáček, Vítězslav Hrubý, Matěj Jendrišák, Rostislav Langer, Michal Langer, Petr Jakubec, Ivan Dědek, Vojtěch Kupka, Michal Mazur, Radek Zbořil, Michal Otyepka   +11 more
wiley   +1 more source

UK Environmental Change Network (ECN) spittle bug data: 1993-2015

, 2018
Spittle Bug data from the UK Environmental Change Network (ECN) terrestrial sites. These data are collected by quadrat sampling at all of ECN's terrestrial sites using a standard protocol .
Corbett, S., Watson, H., Bater, J., Smith, R. I., Smith, P., Scott, T., McKenna, C., Adamson, J., Bowmaker, V., Morecroft, M., Dennis, P., Common, G., Cooper, R., McMillan, S., Murphy, M., Kahl, J., Dodd, N., Schafer, S., Nelson, A., McElarney, Y., Benham, S., Rose, R., Tilbury, C., Langan, S., Anderson, R., Andrews, C., Britt, C., Hargreaves, P., Pearce, I., Brooks, D. R., Dick, J., Easter, J., Flexen, M., Lloyd, D., Tait, R., Beaton, K., Turner, A., Critchley, N., Bayfield, N., Wood, C., Dodd, B., Shortall, C. R., Milne, L., Taylor, C., Rennie, S., Nicholson, H., Sherrin, L., Tyson, K., Beaumont, D. A., Thurlow, M., Donovan, N., Taylor, M., Gardiner, A., Parry, D., Hamilton, D., Milne, F., Pozsgai, G., Brunt, J., Whittaker, M., Lane, M., Brooker, R., Howe, M., Pallett, D.   +62 more
core   +1 more source

Bistable Networks Enable Complex Shape Changes

Advanced Science, EarlyView.
Transition‐controlled metamaterials are networks of bistable mechanical memory that store local binary states and express them as global shape change. By decoupling low‐force programming from high‐force holding, a single lattice is reconfigured into distinct 2D profiles and 3D surfaces without continuous actuation, enabling reusable morphing materials ...
Sawyer Thomas, Jeffrey Lipton
wiley   +1 more source