Results 51 to 60 of about 555,570 (296)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Balancing sustainability and safety: examining the moderating effect of health and safety management on indigenous sustainable construction practices and musculoskeletal injuries

Smart Construction and Sustainable Cities
While indigenous methods are often praised for their ecological sustainability, they are also perceived as physically demanding and potentially unsafe. Thus, this study aims to determine whether effective health and safety management (HSM) can transform ...
Oluseye Olugboyega, Immaculate Nwadike, Abiola Odunayo Ajayi, Paul Tosin Ajayi, Adurapemi Joseph Olusola   +4 more
doaj   +1 more source

A Natural Language Parameter Catalogue for Algorithm-Aided Design of Modular Housing

Buildings
The construction industry is embracing digital technologies, particularly generative or algorithm-aided design principles. However, integrating these digital tools into design processes while ensuring compliance with rules and regulations remains a ...
Sophia Silvia Pibal, David Schuster, Iva Kovacic   +2 more
doaj   +1 more source

CFD simulation of the convective flows in the vertical caverns [PDF]

Инженерно-строительный журнал, 2019
The purpose of this paper is determination the critical geometric dimensions of a three-dimensional vertical heated cavern. In this rate the convection's contribution to heat transfer will be limited due to thermal conductivity at a fixture temperature ...
M.R. Petrichenko, V.V. Sergeev, D. Nemova, E.V. Kotov, D.S. Andreeva   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Final report : your building

, 2007
The Your Building Project to build a website as the business and technical guide to\ud sustainable commercial buildings has now been completed. The site is available at\ud www.yourbuilding.org.

core  

Energy in Construction and Building Materials

Materials, 2023
Energy efficiency in buildings has become a major challenge in both science and industry [...]
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Sustainability and the building code of Australia

, 2003
This report is the culmination of a two-stage research project to inform the Australian property and construction industry generally, in addition to providing the Australian Building Codes Board (ABCB) with information to allow it to determine whether or

core