Results 71 to 80 of about 308,019 (246)

Robotic Large-Scale Additive Manufacturing of Thermoplastics for Thin-Glass Composite Elements

open access: yesChallenging Glass Conference Proceedings, 2022
The use of thin glass promises to enable a variety of construction industry pursuits. In addition to the ecological benefits of more efficient use of resources, architects can anticipate new design freedoms with thin glass. Based on the sandwich theory,
Daniel Pfarr, Christian Louter
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Impact of Cutting Process Parameters on the Mechanical Quality of Processed Glass Edges

open access: yesChallenging Glass Conference Proceedings, 2022
The inspection of glass edges is gaining in importance in research, as the strength of a glass edge has been found to be highly dependent on its processing. Glass edges are produced by cutting.
Paulina Bukieda, Bernhard Weller
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Evaluating Resilience and Thermal Comfort in Mediterranean Dwellings: A Level(s) Framework Approach

open access: yesApplied Sciences
The construction sector plays a pivotal role in urban development, providing a critical opportunity to foster a cultural shift towards the regeneration of housing stock.
Carmen Díaz-López   +3 more
doaj   +1 more source

Constructed: Building Conceptions

open access: yes, 2013
This paper is in support of my thesis exhibition entitled Constructed: Building Conceptions, which was exhibited at the Nickle Galleries at the University of Calgary from the 16th of August 2013 to the 28th of September 2013. In this paper I outline my exhibition Constructed: Building Conceptions, which questions the process through which we perceive ...
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Evaluation of reaction-to-fire behaviour of wood chipboard: A comparative study of treatments and coatings

open access: yesMateriales de Construccion
Fires in buildings pose significant risks to property and human lives, making material selection crucial for fire safety. This study evaluates the fire reaction of wood agglomerate boards, both treated and untreated, under controlled heat exposure.
F.E. Berigüete Alcántara   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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