Results 71 to 80 of about 5,072,317 (340)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
EFFECT OF EXTERNAL SULPHATES ON PROPERTIES OF LIME-POZOLANA CONCRETE [PDF]
Journal of Engineering and Sustainable Development, 2019 This study aims to evaluate the resistance of Lime-Pozzolana concrete mixtures to external sulfate attack, represented by studying their effect on compressive strength, splitting tensile strength, dynamic modulus of elasticity, and weight loss.
Tareq Saleh Al-Attar +2 more
doaj +1 more source
Sustainability, 2020 In Japan, there has been an increase in the number of buildings built using cross-laminated timber (CLT) in order to utilize the abundant forest resources in the country.
K. Nakano +2 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Challenging Glass Conference Proceedings, 2022 This paper presents a study on the development of a bonded edge seal for fluid-filled insulating glass units. Such novel façade elements enable multifunctional building envelopes and an improved energy efficiency of buildings.
Alina Joachim +3 more
doaj
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
, 2020 One of the major issues of the construction industry has been the “reworks” that affect the time, quality, and cost of projects. Therefore, reworks and the ineffective use of site resources and materials will always result in significant losses on ...
H. Khalesi +5 more
semanticscholar +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Bond Stresses between Reinforcing Bar and Reactive Powder Concrete
Journal of Engineering, 2018 A good performance of reinforced concrete structures is ensured by the bond between steel and concrete, which makes the materials work together, forming a part of solidarity.
Hussein Al-Quraishi +2 more
doaj +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source